Snakebite envenoming affects millions of people worldwide annually and is a significant source of mortality. Preventing and treating the problem is complex and requires collaboration among the fields of public health, medicine, ecology, and laboratory science. After being removed from the category A... neglected tropical disease (NTD) list in 2013, snakebite envenoming was reinstated in 2017 in response to antivenom shortages and advocacy from researchers and international NGOs. In 2019, the World Health Organization (WHO) set a target to halve the number of deaths and cases of snakebite envenoming by 2030.
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Humans can become infected with T. saginata or T. asiatica when they consume infected beef meat or pig liver tissue, respectively, which has not been adequately cooked, but taeniasis due to T. saginata or T. asiatica has no major impact on human health. Therefore, this fact sheet refers to the trans...mission and health impacts of T. solium only.
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Taeniasis and cysticercosis caused by the parasite T. solium affect vulnerable populations,
mainly in Latin America, sub-Saharan Africa and Asia, where pigs (the intermediate host) roam
free and poor sanitation allows pigs access to human faeces.
Yaws, a neglected tropical disease (NTD) of the skin caused by the bacterium Treponema pallidum subspecies pertenue, is targeted in the latest WHO NTD Roadmap for eradication by 2030. In January, 2022, WHO published a manual that outlines the key activities that Ministries of Health in endemic count...ries should undertake to achieve this goal. The aim of the manual is to provide guidance on surveillance and evaluation of yaws as programmes progress towards eradication. However, yaws eradication in Africa faces several challenges.
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Yaws is targeted for eradication by 2030, using a strategy based on mass drug administration (MDA) with azithromycin. New diagnostics are needed to aid eradication. Serology is currently the mainstay for yaws diagnosis; however, inaccuracies associated with current serological tests makes it difficu...lt to fully assess the need for and impact of eradication campaigns using these tools. Under the recommendation of the WHO Diagnostic Technical Advisory Group (DTAG) for Neglected Tropical Diseases(NTDs), a working group was assembled and tasked with agreeing on priority use cases for developing target product profiles (TPPs) for new diagnostics tools.
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Rabies is fatal, vaccine-preventable disease responsible for an estimated 59,000 human deaths each year. Most cases are transmitted by dogs, and most deaths occur in underserved populations in Africa and Asia. Approximately 40% of deaths occur in children.
Human African trypanosomiasis (HAT) is a lethal neglected tropical disease (NTD) transmitted by the bite of infected tsetse flies. The disease is also known as “sleeping sickness”. During the 20th century it caused enormous suffering in the endemic areas in sub-Saharan Africa. HAT transmission l...ast soared in the late 1990s, triggering a renewed, coordinated and very successful control effort. In this paper, we present achievements towards HAT elimination, with a focus on the WHO road map targets for 2020. In particular, reported cases continue to decline, from over 30,000 cases per year at the turn of the century to 663 cases in 2020. Despite the impact of the COVID-19 pandemic, HAT surveillance was largely sustained, and the network of health facilities able to diagnose and treat the disease further expanded. Looking to the future, the World Health Organization (WHO) set bold new targets for HAT in its 2021–2030 road map for NTDs, namely: the elimination of transmission of gambiense HAT, which occurs in western and central Africa, and the elimination as a public health problem of rhodesiense HAT, which is found in eastern and southern Africa. The strong commitment of national health authorities and the international community will be essential if these goals are to be achieved.
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Rabies is a devastating and societally important zoonotic disease, which is transmitted principally to humans through the bite of infected dogs. This acute, progressive viral encephalitis has the highest case fatality of any infectious disease and kills tens of thousands of people annually, with chi...ldren and impoverished communities being affected disproportionately.
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Rabies is a vaccine-preventable viral disease which occurs in more than 150 countries and territories. Dogs are the source of the vast majority of human rabies deaths, contributing up to 99% of all rabies transmissions to humans.
Classical rabies caused by RABV occurs worldwide besides some isolated countries and Western Europe that are regarded rabies free. Carnivores, especially of the canidae family represent the principal reservoir species and are responsible for the maintenance of the infectious cycle and hence for the ...presence of the disease (see Epidemiology of rabies). While wildlife rabies maintained by different reservoirs hosts predominantly occurs in the Northern hemisphere, canine rabies is by far more important for public health in the developing world.
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All lyssaviruses have evolved closely with distinct natural reservoir hosts. The latter are animals species in which a pathogen of an infectious disease are maintained independently. For lyssaviruses, these are a wide range of mammalian species within the Carnivora and Chiroptera (bats) orders with ...a global distribution.
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For more than 100 years, the clearest route to elimination of dog-mediated rabies has been via mass vaccination of the animal hosts. It’s worked in plenty of countries. Still, in others, like India, which grapples with a third of the world’s rabies burden, large populations of free-roaming, hard...-to-track, often hard-to-reach dogs have made elimination an elusive goal.
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Rabies is a fatal zoonotic disease most often transmitted to people via bites from infected dogs. This course provides a general introduction to rabies, and the One Health approach currently taken to prevent it. It consists of seven video-lectures, demonstration videos, and lessons learnt from peopl...e who work at the frontline of rabies elimination programmes around the world. It targets both a general audience and those who would like to learn more about rabies and the pathway to eliminating this disease – like prospective and current public health and animal health practitioners in rabies endemic countries.
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World Rabies Day is the biggest event on the global rabies calendar, coordinated by GARC and it has been commemorated every year on September 28 – the anniversary of the death of Louis Pasteur – since 2007. World Rabies Day aims to raise awareness and advocate for rabies elimination globally. It... is an event designed to be inclusive, uniting people, organizations, and stakeholders across all sectors against rabies – because together we can eliminate rabies! With this concept of togetherness and unity in mind, the theme for this year’s World Rabies Day is: Rabies: One Health, Zero Deaths.
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Rabies is a virus (Lyssavirus) that infects cells in the central nervous
system, causing disease in the brain and, ultimately, death. Any animal
with rabies has the ability to transmit the disease to humans or other
animals.
There is no cure for rabies, but it is 100 percent preventable through
...
prompt, appropriate medical care.
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Rabies is transmitted when saliva or neural tissue of an infected animal is introduced into the body. Exposure can occur through a bite, scratch, or contact with saliva to broken skin or mucous membranes such as the eyes or mouth, BUT rabies is preventable! Vaccinations for your pets and livestock a...re key. To report an animal bite or incident between 8:30 AM - 5:00 PM, choose your county's office from the map on the EA Regional Office page and contact them for assistance. On nights, weekends, or holidays, call 1-888-847-0902.
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There is no cure for rabies, but it is 100 percent preventable through prompt, appropriate medical care. Every year hundreds of South Carolinians must undergo preventive treatment for rabies due to exposure to a rabid or suspected rabid animal. Although the cost varies, post-exposure treatment typic...ally exceeds $8,000 per person.
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Rabies is a fatal but preventable viral disease. It can spread to people and pets if they are bitten or scratched by a rabid animal. In the United States, rabies is mostly found in wild animals like bats, raccoons, skunks, and foxes. However, in many other countries dogs still carry rabies, and most... rabies deaths in people around the world are caused by dog bites.
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The incubation period (the time the virus spreads from the peripheral nerves near the site of the bite via the spinal cord to the brain – see transmission and pathogenesis) ranges in general between 2 and 3 month (2 weeks to 6 years are reported) depending on the site of infliction, the amount of ...virus and the virus strain. Due to its neurotropism all known lyssaviruses cause severe neurological symptoms as a result of an acute encephalitis. Therefore, clinical signs in humans and animals are very similar.
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Rabies is a fatal viral disease, but is preventable in humans. The rabies virus is transmitted to humans through virus-laden saliva from a rabid animal, mostly dogs. The virus is shed in the saliva of an infected animal and can be introduced into another body through bites, scratches and any other ...wounds that transect the skin. Contact of the infected saliva with mucous membranes is also thought to be a possible route of infection, whereas contact of infected saliva with intact skin is not considered an exposure. Rabies is preventable through pre-exposure prophylaxis (PrEP) for individuals at high and continual risk, and post-exposure prophylaxis (PEP).
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