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The use of molecular line probe assays for the detection of resistance to isoniazid and rifampicin

World Health Organization (2016) C_WHO
Policy update.
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Molecular assays intended as initial tests for the diagnosis of pulmonary and extrapulmonary TB and rifampicin resistance in adults and children: rapid communication

World Health Organization WHO (2020) C_WHO
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Using recency assays for HIV surveillance: 2022 technical guidance

World Health Organization WHO (2022) C_WHO
Recency assays use one or more biomarkers to identify whether HIV infection in a person is recent (usually within a year or less) or longstanding. Recency assays have been used to estimate incidence in representative cross-sectional surveys and in epidemiological studies to better understand the pat... more
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Rapid Communication: Molecular assays as initial tests for the diagnosis of tuberculosis and rifampicin resistance

World Health Organization WHO (2020) C_WHO
This Rapid Communication aims to inform national TB programmes and other stakeholders about the key implications of the latest evidence on the use of specific molecular assays as initial diagnostic tests of pulmonary and extrapulmonary TB and RR-TB, in adults and children.
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Line probe assays for detection of drug-resistant tuberculosis: interpretation and reporting manual for laboratory staff and clinicians

World Health Organization WHO (2022) C_WHO
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Use of alternative interferon-gamma release assays for the diagnosis of TB infection: WHO policy statement

World Health Organization WHO (2022) C_WHO
Following review of evidence and advice from the Technical Advisory Group (TAG) on Tuberculosis (TB) Diagnostics and Laboratory Strengthening, the World Health Organization (WHO) announces that current WHO recommendations for the use of interferon-gamma release assays (IGRA) are also valid for Beij... more
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The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs

World Health Organization (2016) C_WHO
Policy Guidance.
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Technical Update on HIV incidence assays for surveillance and monitoring purposes

UNAIDS; World Health Organization (2015) C2
UNAIDS/WHO 2015 | Reference
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Selection and use of Ebola in vitro diagnostic (IVD) assays. Emergency guidance

World Health Organization (2015)
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Aktuelle Fragestellungen zum Tuberkulose-Screening mit Interferon-Gamma-Release Assays (IGRAs)

R. Diel, A. Nienhaus (2015) C2
Current Issüs Arising from Tuberculosis Screening with Interferon-Gamma- Release Assays (IGRAs) Pneumologie 2015; 69: 271–275
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Comparison of the Influence of Different Nucleic Acid Extraction Assays on the Sensitivity of Trypanosoma cruzi-Specific Real-Time PCR

Kann, S.; Zabala-Monterroza, W.; García, C. et al. Multidisciplinary Digital Publishing Institute MDPI (2022) CC
For the molecular diagnosis of Chagas disease by real-time PCR (polymerase chain reaction), optimization of diagnostic accuracy is desirable. The detection limit of real-time PCR assays for the diagnosis of Trypanosoma cruzi in human serum is affected by various influences including the choice of th... more
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Operational guidance on the use of yellow fever assays in the context of surveillance

World Health Organization WHO (2023) C_WHO
This publication aims to provide updated guidance on the specific use of yellow fever laboratory assays in the context of surveillance to be used across the Global Yellow Fever Laboratory Network for disease surveillance. In the recent years, new commercial assays became available and are now recomm... more
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Interferon-γ-Tests in der Tuberkulose-Diagnostik - Aktueller Stand

B. Hauer, R. Loddenkemper, A. Detjen, et al. (2006) C2
Interferon-γ Assays - Description and Assessment of a New Tool in the Diagnosis of Tuberculosis. Haür B et al. Interferon-γ-Tests in der ...Pneumologie 2006; 60: 29-44
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Estimating HIV incidence using HIV case surveillance

World Health Organization; UNAIDS (2017) C_WHO
WHO working group on HIV incidence assays meeting report 10–11 December 2015 Glion, Switzerland UNAIDS/WHO working group on global HIV/AIDS and STI surveillance WHO/HIV/2017.03
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SARS-CoV-2 diagnostic pipeline

Find (2020) C_WHO
Many in-house and commercial assays that detect the COVID-19 virus have been developed or are currently under development. Many of these molecular assays are currently being validated in partner laboratories. An overview of assays that have applied to FIND for participation in their assay assessment... more
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Predictive values of Ebola RDTs and implications for decision-makers

World Health Organization (WHO) (2015) C_WHO
Annex to Selection and use of Ebola in vitro diagnostic assays
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Laboratory testing for Zika virus and dengue virus infections: interim guidance
recommended

World Health Organization (2022) C_WHO
Zika and dengue viruses remain significant public health threats. These viruses share the same Aedes (Stegomyia) mosquito vectors and geographic distributions but infections cannot be readily distinguished clinically and need to be differentiated from each other, and from other circulating arboviral... more
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COVID-19 new variants: Knowledge gaps and research

World Health Organization WHO (2021) C_WHO
n light of the potential risk posed by SARS-CoV-2 variants, in January 2021 WHO organized an ad hoc consultation to discuss the development of an R&D agenda in response to existing and emerging SARS-CoV-2 variants. The key objectives were to identify the critical research questions related to var... more
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Updated recommendations on simplified service delivery and diagnostics for hepatitis C infection
recommended

World Health Organization WHO (2022) CC
Policy Brief. 24 June 2022. This policy brief, one of two on the updated hepatitis C (HCV) guidelines, focuses on the new recommendations on simplified service delivery for a public health approach to HCV testing, care and treatment. These recommendations include decentralization, integration and ta... more