Rabies is a zoonotic, vaccine-preventable viral disease that causes damage to the brain and spinal
cord in infected animals and humans. A zoonotic disease is a disease that can be transmitted
between animals and humans. Rabies is nearly 100% fatal... once symptoms appear.
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WHO strongly recommends discontinuation of the nerve tissue vaccine, and replacement with modern concentrated and purified cell culture derived vaccines (CCDV) and embryonated eggbased rabies ...class="attribute-to-highlight medbox">vaccines.
These vaccines must comply with WHO criteria for potency and innocuity following satisfactory assessment in humans during well-designed field trials
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The backsliding of immunization coverage during the COVID-19 pandemic, combined with delayed catch-up efforts has resulted in a large and growing immunity gap. There is an urgent need to close this gap, and enable millions of missed children to be vaccin...span>ated. The Essential Immunization Recovery Plan sets out a path to getting immunization back on track, framed by three key approaches – Catch-Up, Restore and Strengthen. This document serves as the joint strategic description of this coordinated effort by WHO, UNICEF, and Gavi, the Vaccine Alliance, along with the Immunization Agenda 2030 (IA2030) Partnership, to support countries to plan and implement intensified efforts to bolster immunization programmes in 2023 and beyond.
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Introduction Pharmacovigilance (PV) systems to monitor drug and vaccine safety are often inadequate in sub-Saharan
Africa. In Malawi, a PV enhancement initiative was introduced to address major barriers to PV.
Objective The objective of this initi...ative was to improve reporting of adverse events (AEs) by strengthening passive safety
surveillance via PV training and mentoring of local PV stakeholders and healthcare providers (HCPs) at their own healthcare
facilities (HCFs).
Methods An 18-month PV training and mentoring programme was implemented in collaboration with national stakeholders,
and in partnership with the Ministry of Health, GSK and PATH. Two-day training was provided to Expanded Programme on
Immunisation coordinators, identified as responsible for AE reporting, and four National Regulatory Authority representa-
tives. Abridged PV training and mentoring were provided regularly to HCPs. Support was given in upgrading the national
PV system. Key performance indicators included the number of AEs reported, transmission of AE forms, completeness of
reports, serious AEs reported and timeliness of recording into VigiFlow.
Results In 18 months, 443 HCPs at 61 HCFs were trained. The number of reported AEs increased from 22 (January 2000 to
October 2016) to 228 (November 2016 to May 2018), enabling Malawi to become a member of the World Health Organization
Programme for International Drug Monitoring. Most (98%) AE report forms contained mandatory information on reporter,
event, patient and product, but under 1% were transmitted to the national PV office within 48 h.
Conclusion Regular PV training and mentoring of HCPs were effective in enhancing passive safety surveillance in Malawi,
but the transmission of reports to the national PV centre requires further improvement.
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In many countries neonatal tetanus is responsible for half of all neonatal deaths due to vaccine-preventable diseases and for almost 14% of al¡ infant deaths. It is estimated that in the 1970s more than 10,000 newborns died annually from neonatal t...etanus in the Americas. Neonatal tetanus is prevented by immunization and/or assuring clean delivery and post-delivery practices.
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1 March 2021
This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and e...quitable access – in WHO’s Vaccines Explained series.
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31 March 2021
This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and ...equitable access – in WHO’s Vaccines Explained series.
COVID-19 vaccines are safe, and getting vaccinated will help protect you against developing severe COVID-19 disease and dying from COVID-19. You may experience some mild side effects after getting vaccinated, which are signs that your body is building protection.
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31 March 2021
This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and ...equitable access – in WHO’s Vaccines Explained series.
Countries around the world are rolling out COVID-19 vaccines, and a key topic of interest is their safety. Vaccine safety is one of WHO’s highest priorities, and we’re working closely with national authorities to develop and implement standards to ensure that COVID-19 vaccines are safe and effective.
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Tackling COVID-19 misinformation. Ensuring communities have access to lifesaving public health information from trusted sources and are not misled by misinformation is essential to ending the COVID-19 pandemic.
In an effort to empower doctors and nurses – some of the most effective and trusted... messengers of public health information – to actively address COVID-19 misinformation and build vaccine confidence globally, the WHO welcomes this social media toolkit for healthcare practitioners, developed by the Government of the United Kingdom.
This toolkit aims to provide healthcare workers with the tools, skills and content needed to effectively share authentic and reliable information online. Centered around three core vaccine confidence messages, Vaccine Safety, Vaccine Development and Vaccine Reducing Risk of Sickness; this toolkit sets out three approaches: creating your own posts, posting the images and videos provided in the toolkit, or resharing vaccine information from trusted sources.
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Vaccinator's Manual. Pfizer-BioNTech Comirnaty Vaccine
This is a part of a series of lesson plans created by Peace Corps volunteers in Senegal about vaccine preventable diseases
Since May 2019, Confirmation of 4 new emergence of type 2 vaccine-derived poliovirus (VDPV2) in Bambari (2) and Bimbo (2) health districts without any genetic link between them and other known viruses ; Bambari Health District: CAF-RS4-BAM-19-058, o...nset of paralysis: May 02, 2019. 07 positive contacts with the same genetic link. Community samples CAF-RS4-BAM-19-058CC14 and CAF-RS4-BAM-19-058CC17 positive, genetically related to each other but not genetically linked to the CAF-RS4-BAM-19-058 index case (new emergence)
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La vaccination est un service de santé essentiel qui protège les sujets sensibles contre les maladies à prévention vaccinale (MPV).2 La vaccin...n>ation en temps voulu permet aux individus et aux communautés de rester protégés et diminue la probabilité d’une poussée épidémique de MPV.
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The Guidance on National Deployment and Vaccination Planning is intended to help countries develop their plan for COVID-19 vaccine introduction.
26 March 2021
If you have already had COVID-19 do you still need both doses of the vaccine? Do these vaccines protect you against infection? Do they protect us against variants? WHO’s Dr Katherin...e O’Brien answers these questions in Science in 5 this week.
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The purpose of this Standard Operating Procedure (SOP) is to describe the detailed process on how to manage discarded COVID-19 vaccine vials and associated waste after COVID-19 vaccination activitie...s end. The SOP provides clear instructions on how to perform the appropriate treatment and safe disposal of these wastes to minimize any associated health risk with consideration to local context.
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L’objectif du présent Mode opératoire normalisé (MON) est de décrire le processus détaillé de gestion des flacons de vaccin anti-COVID-19 et des déchets associés jetés au terme d’activités de ...ht medbox">vaccination contre la COVID-19. Le mode opératoire normalisé fournit des instructions claires sur le traitement approprié et l’élimination en toute sécurité de ces déchets afin de minimiser tout risque sanitaire associé en tenant compte du contexte local.
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The overall goal of this strategy is to ensure accurate understanding of the
benefits of covid-19 vaccination and alleviate apprehension about the vaccine, to ensure its acceptance and encourage up...take across various audiences.
Objectives
x Create demand, promote acceptability and accessibility of COVID-19
vaccine among at least 90% of the general public.
x Develop appropriate messages and identify channels to communicate
the potential benefits and risks of the vaccine to all concerned parties,
including decision-makers at all levels.
x Provide timely and accurate information to address misinformation,
rumors and other crisis situations.
x Effectively mobilize and empower communities to ensure participation
and ownership of the vaccination process
x Strengthen communication mechanisms and partnerships among key
stakeholders to support the national communication effort.
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When situations occur in which unwanted events are rightly or wrongly connected with vaccination, they may erode confidence in vaccines and the authorities delivering them. This document presents th...e scientific evidence behind WHO’s recommendations on building and restoring confidence in vaccines and vaccination, both in ongoing work and during crises. The evidence draws on a vast reserve of laboratory research and fieldwork within psychology and communication. It examines how people make decisions about vaccination; why some people are hesitant about vaccination; and the factors that drive a crisis, covering how building trust, listening to and understanding people, building relations, communicating risk and shaping messages to the audiences may mitigate crises. This document provides a knowledge base for stakeholders who develop communication strategies or facilitate workshops on communication and trust-building activities in relation to vaccines and immunization, such as immunization programme units, ministries of health, public relations and health promotion units, vaccine safety communication trainers and immunization advisory bodies.
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The interactive report calls for ramped-up investment in health infrastructure worldwide to address yawning resource gaps in vaccine research, development, and manufacturing capacity.
Key findings:
• The pandemic pushed an additional 31 million... people into “dire poverty” and backpedaled progress toward eliminating poverty by 4 years
• Global rates for routine childhood vaccinations, such as malaria, fell last year by 7%, to levels not seen since 2005.
You can find a lot of excellent information and graphics
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