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To support its R&D activities on Chagas disease, DNDi launched the Chagas Clinical Research Platform (CCRP). The platform brings together partners, experts, and stakeholders to provide support for evaluation and development of new treatments for Chagas disease. The patient-centred platform aims to f... more
Chagas disease is a neglected tropical disease cause by the Trypanosoma cruzi parasite. It is spread mostly by insects known as Triatominae, or kissing bugs. If left untreated, Chagas can cause serious problems to the heart and digestive system.
About six to seven million people worldwide, mostly in Latin America, are estimated to be infected with Trypanosoma cruzi, the parasite that causes Chagas disease (WHO data from 2021). Chagas disease is found mainly in endemic areas of 21 Latin American countries. Chagas disease was once entirely ... more
Info Chagas What do we need to know abaout Chagas Disease? What is Chagas Disease?
How Chagas disease is transmitted video. Video available with spanish sub title
The BeatChagas platform is a tool developed by the Technical Group of Information, Education, and Communication (IEC) for Chagas Disease (TG6-IEC Chagas), part of the Chagas Disease Control Program by the World Health Organization (WHO). The purpose of this platform is to share information about the... more
Chagas disease (CD) is endemic in the Americas, being present in 21 countries, where it affects about 6 million people.(1) With such relevant numbers of people affected and disability adjusted life years lost, CD is a poverty-related and poverty-promoting disease. Although data describe a relevan... more
Research and Reports in Tropical Medicine 2022:13 25–40. Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central, South America, Mexico and the South of the United States. It is an important cause of early mortality and morbidity, and it is associated with po... more
DOI: 10.5772/intechopen.102891Little progress has been made since the 1960s and 19. 70s to widen the therapeutic arsenal against Trypanosoma cruzi, the causative pathogen of Chagas disease, which remains a frustrating and perplexing infectious disease. This chapter focuses on the strategic and opera... more
This review focusses on the interactions between the etiologic agent of Chagas disease, Trypanosoma cruzi, and its triatomine vector. The flagellate mainly colonizes the intestinal tract of the insect. The effect of triatomines on trypanosomes is indicated by susceptibility and refractoriness phenom... more
Datos y cifras Se calcula que en el mundo hay entre 6 y 7 millones de personas infectadas por el Trypanosoma cruzi, el parásito causante de la enfermedad de Chagas, la mayoría de ellas en América Latina. La infección por Trypanosoma cruzi se puede curar si el tratamiento se administra al poco ... more
Principaux faits D’après les estimations, 6 à 7 millions de personnes dans le monde sont infectées par Trypanosoma cruzi (T. Cruzi), le parasite responsable de la maladie de Chagas. La plupart de ces personnes vivent en Amérique latine. La transmission à l’être humain se fait principalem... more
Болезнь Шагаса, известная также как американский трипаносомоз, — потенциально опасное для жизни заболевание, вызываемое простейшим паразитом Trypanosoma cruzi.
إن داء شاغاس المعروف أيضا باسم داء المثقبيات الأمريكي، مرض قد يكون مهدداً للحياة يسببه الطفيلي الأوّالي المعروف باسم المِثْقَبِيَّة الكروزيَّة.
This manual provides a framework for morbidity management and disability prevention of patients affected by NIDs and gives specific guidance for the proper care of patients suffering from chronic conditions caused by lymphatic filariasis, leprosy, trachoma, and Chagas disease. It is intended to be u... more
La transmisión de T. cruzi de un donante con la enfermedad de Chagas a un receptor de trasplante es poco frecuente y es resultado de la aplicación de un tratamiento quirúrgido. En este documento se proponen diez pautas para manejar y prevenir la transmisión de la enfermedad de Chagas por traspla... more
This manual provides a framework for morbidity management and disability prevention of patients affected by NIDs and gives specific guidance for the proper care of patients suffering from chronic conditions caused by lymphatic filariasis, leprosy, trachoma, and Chagas disease. It is intended to be u... more
A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data platform. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations s... more
Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493 .Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech... more
Chagas Disease (CD) affects 6–7 million people worldwide and isrelated topoverty-promo ting conditions. Chronic asymptomatic cases are mostly invisible tohealth systems. Aiming totranslate CD discoveries into education/information practices toraise alertness and empowerment ofaffected people; and ... more