The objective of this document is to guide the preparation and implementation of national preparedness plans for the safety of substances of human origin during outbreaks of Zika virus infection, bo
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th in affected and non-affected areas.
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Updated 6 September 2016. This guidance has been developed to provide advice on the prevention of potential sexual transmission of Zika virus. The primary transmission route of
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Zika virus is via the Aedes mosquito. However, sexual transmission of Zika virus may also be possible, with limited evidence recorded in a few cases. This is of concern due to an association between Zika virus infection and potential complications, including microcephaly and Guillain-Barré syndrome.
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Testing Guidance and Interpretation of Results for Healthcare Providers
Zika Virus Testing Guidance: Asymptomatic Pregnant Women
with Possible Zika
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Virus Exposure
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This document provides interim recommendations for the surveillance of Zika virus infection, microcephaly and Guillain-Barré syndrome, in four different contexts and describes reporting requirement
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s to WHO. Transmission refers to vector-borne transmission, unless specified differently. Autochthonous infection is considered to be an infection acquired in-country, i.e. among patients with no history of travel during the incubation period or who have travelled exclusively to non-affected areas during the incubation period. This document does not provide guidance on laboratory investigation or vector surveillance.
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BMC Medicine201614:112 DOI: 10.1186/s12916-016-0660-0
Zika and dengue viruses remain significant public health threats. These viruses share the same Aedes (Stegomyia) mosquito vectors and geographic distributions but infections cannot be readily distinguished clinically and need to be differentiated fr
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om each other, and from other circulating arboviral and non-arboviral pathogens, using laboratory tests. This document provides guidance on current testing strategies for Zika and dengue virus infections with updates to the previous interim guidance for laboratory testing for ZIKV, addressing pregnant and non-pregnant patients respectively, and incorporates current guidance for dengue virus diagnostic testing. The choice of laboratory assays and interpretation of test results require careful consideration of epidemiology, patient history, and limitations of existing diagnostic tests.
This interim guidance is for use by staff of laboratories testing for Zika and dengue virus infections and for clinical practitioners and public health professionals providing clinical management or surveillance.
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Guía Nacional para el Manejo de la Infeccion por el Virus Zika
The threat posed by Zika virus infection highlights the need to reinforce preparedness arrangements for mosquito-borne diseases in EU/EEA countries, especially for pathogens transmitted by Aedes aeg
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ypti and Aedes albopictus.
The aim of this document is to highlight measures that can effectively reduce the risk of importation and local transmission of pathogens transmitted by Ae. aegypti and Ae. albopictus. The main diseases of concern in this context are Zika, dengue, chikungunya and yellow fever.
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Interim guidelines developed by CDC for healthcare providers in the United States caring for infants born to mothers who while pregnant traveled to or resided in an area with Zika virus transmission
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. These guidelines include recommendations for the evaluation, testing, and management of infants with and without microcephaly or intracranial calcifications detected.
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Lignes directrices provisoires actualisées 7 juin 2016
This document aims to present an algorithm for deciding whom to test and provide guidance on the laboratory tests for Zika virus infection diagnosis in order to support clinical diagnostic and case
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reporting through surveillance among EU Member States. The algorithm is not intended for clinical management of patients with suspected Zika virus infection.
The information is provisional and subject to revision when new information becomes available.
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Actualización de las orientaciones provisionales 7 de junio de 2016
La récente augmentation du nombre de cas de microcéphalie et d’autres troubles neurologiques potentiellement associés à une infection à virus Zika a engendré une recrudescence des demandes
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de dépistage en laboratoire de cette infection. Les groupes prioritaires pour un test de diagnostic doivent être constitués de personnes symptomatiques et de femmes enceintes asymptomatiques potentiellement exposées au virus Zika.
Ce document fournit des indications sur les stratégies actuelles de dépistage de l’infection à virus Zika. Il sera revu et actualisé à mesure que des informations supplémentaires deviendront disponibles.
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