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Vaccins antirabiques: Note de synthèse de l’OMS – avril 2018
Weekly epidemiological record / Relevé épidémiologique hebdomadaire
20 APRIL 2018, 93th YEAR / 20 AVRIL 2018, 93e ANNÉE
Weekly epidemiological record / Relevé épidémiologique hebdomadaire
20 APRIL 2018, 93th YEAR / 20 AVRIL 2018, 93e ANNÉE
The new WHO recommendations for rabies immunization supersede the 2010 WHO position
on pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) for rabies. These updated
recommendations...
Video
Further OIE Support for African Countries on Rabies vaccines
For more than 100 years, the clearest route to elimination of dog-mediated rabies has been via mass vaccination of the animal hosts. It’s worked in plenty of countries. Still, in others, like India, which grapples with a third of the world’s ... burden, large populations of free-roaming, hard-to-track, often hard-to-reach dogs have made elimination an elusive goal.
Rabies is entirely preventable, and vaccines, medicines, tools and technologies have long been available to prevent people from dying of dog-mediated rabi.... Nevertheless, rabies still kills about 60 000 people a year, of whom over 40% are children under 15, mainly in rural areas of economically disadvantaged countries in Africa and Asia. Of all human cases, up to 99% are acquired from the bite of an infected dog.
Rabies is entirely preventable, and vaccines, medicines, tools and technologies have long
been available to prevent people from dying of dog-mediated rab.... Nevertheless, rabies still
kills about 60 000 people a year, of whom over 40% are children under 15, mainly in rural areas
of economically disadvantaged countries in Africa and Asia. Of all human cases, up to 99% are
acquired from the bite of an infected dog.
A regimen of four 1-mL doses of HDCV or PCEC vaccines should be administered intramuscularly to previously unvaccinated persons.
The first dose of the four-dose course should be administered as soon as possible after exposure. Additional doses sh...
WHO strongly recommends discontinuation of the nerve tissue vaccine, and replacement with modern concentrated and purified cell culture derived vaccines (CCDV) and embryonated eggbased rabies ....
These vaccines must comply with WHO criteria for potency and innocuity following satisfactory assessment in humans during well-designed field trials
Rabies is a public health problem in Asia and vaccine affordability is an issue.
There is no reduction in the number of persons seeking post-exposure prophylaxis.
The high cost of cell culture vaccines...
An estimated 59 000 people die from rabies each year. That’s one person every nine minutes of every day, 40% of whom are children living in Asia and Africa. As dog bites cause almost all human cases, we can prevent ... deaths by increasing awareness, vaccinating dogs to prevent the disease at its source and administering life-saving treatment after people have been bitten. We have the vaccines, medicines, tools and technologies to prevent people from dying from dog-mediated rabies. For a relatively low cost it is possible to break the disease cycle and save lives
Overview
The aim of this guide is to support national immunization programme managers and others responsible for implementing human rabies vaccine programmes to:
inform policy discussions and operational planning for introducing or expanding ... post-exposure prophylaxis (PEP) into a national immunization programme (e.g. through the national immunization programme, or other programmes); and
highlight considerations specific to rabies PEP for integration into existing systems, including for implementation, and monitoring and evaluation.
While the guide is mainly intended for programme managers and focuses on human vaccination, complementary animal health measures are highlighted where relevant given the zoonotic nature of rabies.
The guide was developed collaboratively with input from technical experts in rabies and immunization, vaccines and biologicals.
Rabies is a neglected zoonotic disease responsible for an estimated 59,000 human deaths annually. Rural populations in Africa and Asia are predominantly affected, and approximately
40% of cases occur in children under the age of 15 years. Transmitt...
WHO TRS N°1012.
Key updates include: (i) surveillance strategies, including cross-sectoral linking of systems and suitable diagnostics; (ii) the latest recommendations on human and animal immunization; (iii) palliative care in lowresource settings; (iv) risk assessment to guide management of bite...
These new guidelines should help medical and paramedical professionals to provide the state of art rabies prophylaxis to all animal bite victims in the government hospitals and prevent human rabies ...
Website last accessed in 12.03.23
CDC’s Lauren Greenberg writes about building rabies diagnostic capacity in the effort to control rabies in countries that are most affected by the disease.
‘World Rabies Day’ is observed worldwide to mark the death anniversary of Louis Pasteur, a
French biologist, microbiologist and chemist who developed the first rabies vaccine. It’s a day wher...
Driving progress towards rabies elimination: Results of Gavi’s Learning Agenda on rabies and new WHO position on rabies immunization
Rabies is a global public health problem with important socioeconomic impacts. Human rabies is preventable; almost all cases are transmitted through the bite of a rabid dog. Elimination of human ... is possible. Technical support and tools are available. This report covers:
- Why investment is needed: key rationale.
- Investment purpose: global elimination of rabies.
- Investment in action: four case examples in Philippines, Kwa-Zulu Natal, South Africa, United Republic of Tanzania, Bangladesh.
- Summary results of case examples: Programme similarities and differences, and Health impact success stories from case examples.
- Why investment is needed: key rationale.
- Investment purpose: global elimination of rabies.
- Investment in action: four case examples in Philippines, Kwa-Zulu Natal, South Africa, United Republic of Tanzania, Bangladesh.
- Summary results of case examples: Programme similarities and differences, and Health impact success stories from case examples.
