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Considerations for developing a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential

World Health Organization WHO (2023) C_WHO
Pathogen genomic surveillance has become a priority for public health systems in recent years. Genomic sequencing is increasingly being used to characterize pathogens and monitor important public health priorities (e.g. poliovirus, influenza virus, Mycobacterium tuberculosis and Vibrio cholerae, ant... more
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The Africa Pathogen Genomics Initative (Africa PGI) Integrated Genomic Surveillance for Outbreak Detection (DETECT)

Africa Center for Disease Control and Prevention (2024) CC
Africa CDC Institute of Pathogen Genomics (IPG) was launched in November 2019 and operates under the Division of Laboratory Systems and Networks. IPG coordinate the implementation of molecular diagnostics, pathogen genomics and bioinformatics in National Public Health Institutions (NPHIs) and/or Re... more
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Pathogenesis of chronic obstructive pulmonary disease: An African perspective

Allwood, B.; Calligaro, G. South African Medical Journal (SAMJ) (2015) CC2
The article discusses the significant impact of chronic obstructive pulmonary disease (COPD) as a global health issue, with cigarette smoking as the main risk factor. However, in developing countries, the causes of COPD are often multifactorial, involving environmental tobacco smoke, biomass fuel sm... more
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Resistant pathogens

BUKO Pharma-Kampagne (2020) C2
BUKO Pharma-Kampagne has investigated the causes and consequences of antibiotic resistance in India, South Africa, Tanzania and Germany. Together with our partners we collected data and did interviews with numerous stakeholders. The outcome is presented in a brochure that is now available in English... more
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Epidemiology, pathogenesis, and clinical manifestations of Ebola and Marburg virus disease

M. Bray, M.S.Hirsch, D.Mitty (2014)
The publisher have agreed to the request, and the full content of the Ebola section is now freely available here
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Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis

World Health Organization (2017) C_WHO
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Global genomic surveillance strategy for pathogens with pandemic and epidemic potential, 2022–2032

World Health Organization WHO (2022) C_WHO
The Strategy provides a high-level unifying framework to leverage existing capacities, address barriers and strengthen the use of genomic surveillance in the detection, monitoring and response to public health threats. Genomic surveillance is part of the broader surveillance and laboratory system, a... more
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A checklist for respiratory pathogen pandemic preparedness planning

World Health Organization WHO (2023) C_WHO
This checklist is an operational tool to help national authorities develop or revise national respiratory pathogen (inclusive of influenza and coronaviruses) pandemic preparedness plans.
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Developing respiratory pathogen pandemic preparedness plans

Pan American Health Organization (PAHO) (2024) C_WHO
Planning for public health emergencies should ensure that capabilities developed during previous emergencies are maintained, incorporated, and put into practice when a new event of public health concern arises. Investments in pandemic preparedness lead to more rapid detection and a stronger response... more
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The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

K.Dheda, T. Gumbo, G. Maartens, et al. The Lancet Respiratory Medicine Commission (2017) C2
Lancet Respir Med 2017; 5: 291–360Vol, 5 April 2017
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Leptospiral Infection, Pathogenesis and Its Diagnosis

Samrot, A.; Sean, T.; Bhavya, K.; et al. (2021) CC
Leptospirosis is a perplexing conundrum for many. In the existing literature, the pathophysiological mechanisms pertaining to leptospirosis is still not understood in full. Considered as a neglected tropical zoonotic disease, leptospirosis is culminating as a serious problem worldwide, seemingly exi... more
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Strengthening pandemic preparedness planning for respiratory pathogens: policy brief, 27 April 2022

World Health Organization WHO (2022) C_WHO
This policy brief outlines core elements that Member States are encouraged to a) develop an integrated approach to respiratory pathogen pandemic preparedness planning and b) enhance national and sub-national functional capacities for preparedness. In addition, this policy brief highlights suggested ... more
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Responding to outbreaks of antimicrobial-resistant pathogens in health-care facilities: guidance for the Western Pacific region

World Health Organization WHO (2022) C_WHO
Responding to Outbreaks of Antimicrobial-resistant Pathogens in Health-care Facilities: Guidance for the Western Pacific Region is developed following requests from Member States in the Western Pacific Region for additional information and support in managing AMR outbreaks. It aims to provide: a ste... more
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Preparedness and Resilience for Emerging Threats Module 1: Planning for respiratory pathogen pandemics

World Health Organization WHO (2024) C_WHO
Through technical consultations with countries and partners, WHO has led the development of Preparedness and Resilience for Emerging Threats Module 1: Planning for respiratory pathogen pandemics. Version 1.0. The Module, currently available as an advanced draft, builds on previous pandemic lessons a... more
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Global technical consultation report on proposed terminology for pathogens that transmit through the air

World Health Organization WHO (2024) C_WHO
Terminology used to describe the transmission of pathogens through the air varies across scientific disciplines, organizations and the general public. While this has been the case for decades, during the coronavirus disease (COVID-19) pandemic, the terms ‘airborne’, ‘airborne transmission’ a... more
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Geographical Distribution of Cutaneous Leishmaniasis and Pathogenesis

Flaih, M. (2021) CC
Leishmaniasis is still considered to be a global health problem, which spreads in most countries in the world. Leishmania is an intracellular obligate protistan parasite that causes different clinical symptoms in infected humans and other animals. There are clinically different types of the disease ... more
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Management and Control of Viral Haemorrhagic Fevers and other highly contagious viral pathogens

European Network for Diagnostics of Imported Viral Diseases (2001) C1
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The regulatory and certification framework for institutions handling high risk pathogens in the Africa Region

African Union; Africa CDC Centres for Disease Control and Prevention (2022) CC
he Framework sets the requirements for facilities handling High Consequence Agents and Toxins (HCATs) and guides the implementation of laboratory biosafety and biosecurity practices associated with the design, commissioning, routine operation safe and secure biocontainment laboratories.
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Leishmaniasis in Eurasia and Africa: geographical distribution of vector species and pathogens

Cunze, S.; Kochmann, J.; Koch, L. et al. Royal Society open Science (2019) CC
Leishmaniasis is a vector-borne disease with a broad global distribution and an increasing number of recorded cases worldwide. However, it is still one of the world's most neglected diseases. Over the last decades, the disease has been found to expand geographically with a global increase of cases o... more
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How to safely collect blood samples from persons suspected to be infected with highly infectious blood-borne pathogens (e.g. Ebola)

World Health Organization (2014) C_WHO