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Rabies Educational Material

Department of Health and Environmental Control dhec (2022) CC

Rabies is transmitted when saliva or neural tissue of an infected animal is introduced into the body. Exposure can occur through a bite, scratch, or contact with saliva to broken skin or mucous membranes such as the eyes or mouth, BUT rabies is prev... more

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Management & Post-Exposure Prophylaxis of Potential HIV and Hepatitis B Exposure in Children, Adolescents & Adults Guidelines (South Africa)

Western Cape Government Health, South Africa (2019) C1

1PEP GUIDELINES | 2019 EDITION. The prevalence of both HIV and Hepatitis B is high in South Africa therefore there is a significant risk of acquiring these infections following exposure to infected materia.... Studies suggest that post- exposure prophylaxis (PEP) with highly active antiretroviral treatment (HAART) is highly effective in preventing HIV infection if taken correctly for the full recommended duration of 28 days, and that prophylaxis with Hepatitis B immunoglobulin and vaccination may prevent Hepatitis B infection if given soon after exposure. This update of the Western Cape guidelines for management of potentially infectious exposures is based on current evidence and guidelines issued by the WHO, NDoH and the SA HIV Clinicians Society. The key aim is to promote successful completion of the recommended ART regimen in the 28 day period of therapy, as well as prevent infection with Hepatitis B more

Monkeypox multi-country outbreak. Rapid Risk Assessment

European Centre for Disease Prevention and Control (ECDC) (2022) C2

Cases of monkeypox (MPX) acquired in the EU have recently been reported in nine EU Member States (Austria, Belgium, France, Germany, Italy, Portugal, Spain, Sweden, and the Netherlands). Monkeypox (MPX) does not spread easily between people. Human-to-human transmission occurs through close contact ... more

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Ebola Virus Disease: Personal Protective Equipment, UNICEF Specifications (March 2015)

UNICEF (2015)

UNICEF provides a detailed update and list of Ebola virus disease personal protective equipment technical specifications for use in high- and low-risk settings. It includes barriers for full body protection, as well as the head, nose, mouth, eyes, hands and feet. In selecting the right PPE specifica... more

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Monkeypox: Introductory course for African outbreak contexts

World Health Organization (WHO) (2020) C_WHO

Monkeypox virus is an orthopoxvirus that causes human monkeypox, a viral disease with symptoms similar to smallpox, including fever and rash. Following the worldwide eradication of smallpox in 1980, monkeypox emerged as the most significant orthopoxvirus infection in humans. Cases are most often rep... more

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Laboratory Tests Used in the Diagnostic and Research of Dengue Virus: Present and Future

Juan Samuel Sulca Herencia IntechOpen (2018) CC

Dengue is a significant public health problem. There are four dengue virus serotypes identified; however, its diagnosis is difficult due to the existence of many viruses, bacteria, and parasites producing the same clinical presentation, being present in the same geographical area and even producing ... more

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Dengue Explained in 5 Minutes

FreeMeEducation (2020) CC

There are currently 4 different serotypes of Dengue virus known to science. Each time someone get infected and recovers, the individual will be protected by a lifelong immunity from further infection against that specific serotype and that serotype ... more

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WHO in Science Episode #44 - Delta variant and vaccines

World Health Organization WHO (2021) C_WHO

Do the current batch of approved vaccines protect us from the Delta variant? What is the level of protection? If you can still get infected even after being fully vaccinated, then why should we vaccinate? WHO’s Chief Scientist Dr Soumya Swaminatha... more

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DRC: Plan de gestion des déchets biomedicaux

Ministère de la Santé Publique, Republique Démocratique du Congo (2016) C1

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We can prevent mothers from dying and babies from becoming infected with HIV

UNAIDS UNAIDS; Unicef; WHO et. al (2010) C2

Joint Action for Results UNAIDS Outcome Framework: Business Case 2009–2011

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Technical update on treatment optimization: use of tenofovir disoproxil fumarate in HIV-infected children and adolescents aged 2–18 years: a public health perspective

World Health Organization (2012)

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Diagnosis Prevention and Management of Cryptococcal Disease in HIV-infected Adults and Children

WHO (2011)

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Guidelines on Co-trimoxazole prophylaxis for HIV-exposed and HIV-infected infants and children: Practical approaches to implementation and scale up

World Health Organization; UNICEF (2009) C_WHO

WHO recommendations on the management of diarrhoea and pneumonia in HIV-infected infants and children

World Health Organization (2010) C_WHO

To improve survival and quality of life among the 2.5 million children living with HIV, a comprehensive package of prevention, care and treatment is required. This package should include management of infections such as pneumonia, diarrhoea, malaria and ear infections, as well as common opportunisti... more

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Antiretroviral Therapy Guidelines for HIV-Infected Adults and Adolescents Including Post-exposure Prophylaxis

Ministry of Health & Family Welfare Government of India Ministry of Health & Family Welfare Government of India (2007) C1

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How to safely collect sputum samples from patients suspected to be infected with pneumonic plague

World Health Organization WHO (2016) C_WHO

Interim Guidance

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Assessment of Effectiveness of IEC material PMU/M & E/7- Effectiveness of IEC material at Red Ribbon Clubs (RRCs)

Unicef; ORG Centre for Social Research (2019)

Final Report Submitted to: Unicef, New Delhi ORG Centre for Social Research (A Division of AC Nielsen ORG- MARG Private Limited) Accessed: 30.10.2019

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Handbook - Guidelines for an Integrated Approach to the Nutritional care of HIV-infected children (6 months-14 years)

World Health Organization (2009)

Preliminary version for country introduction

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Guide for local adaptation - Guidelines for an Integrated Approach to the Nutritional care of HIV-infected children (6 months-14 years)

World Health Organization WHO (2009)

In the area of nutrition and HIV, children deserve special attention because of their additional needs to ensure growth and development and their dependency on adults for adequate care. It was therefore proposed to first develop guidelines for children and thereafter consider a similar approach for... more