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Essential Package of Health Services, Country Snapshot: Liberia

Wright, J.; Bethesda, MD: Health Finance & Governance Project, Abt Associates Inc. USAID (2015) C1

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study

Kamali, M.; J. E Wright, N. Aksee, et al. (2020) CC

Lancet Glob Health 2020Published OnlineDecember 10, 2020 https://doi.org/10.1016/S2214-109X(20)30460-5

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Situation Analysis of Disability Resources and Needs of Shantytowns near Lima, Peru

Hunt, J. Write State University Dayton (2011) C1

Master Publication

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A Community Guide to Environmental Health

Conant, J.; Fadem, P. Hesperian (2012) C2

With hundreds of illustrations and clear instructions, A Community Guide to Environmental Health helps health promoters, development workers, environmental activists, and community leaders take charge of their environmental health in villages and cities alike. Also available in Arabic, Spanish, Chin... more

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Guía comunitaria para la salud ambiental

Conant, J.; Fadem, P. Hesperian (2011) C2

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Developing Global Health Programming

Evert, J.; P. Drain, and T. Hall (2014) CC

A Guidebook for Medical and Professional Schools, Second Edition. This book represents a significant step to engage health professions schools in addressing global health challenges

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First Antiretroviral Therapy Changes in People Living with HIV in Senegal: Incidence, Causes and Predictive Factors

Diouf A., T. J. Youbong, F. L. Dieye et. al. Journal of AIDS & Clinical Research (2017) C2

In resource-limited countries, the number of available antiretroviral (ARV) drugs is relatively limited. Hence, caregivers face some caution and constraints in the changes of ARV treatment (ART) in people living with HIV (PLHIV). Our objective was to calculate the incidence, to describe the main cau... more

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Q&A: Antibiotic resistance: where does it come from and what can we do about it?

Wright G.D. BMC Biology (2010) C2

Historically, the discovery of the sulfa drugs in the 1930s and the subsequent development of penicillin during World War II ushered in a new era in the treatment of infectious diseases. Infections that were common causes of death and disease in the pre-... more

Health facility preparedness for cholera outbreak response in four cholera-prone districts in Cameroon: a cross sectional study

Ateudjieu, J.; M. Ndinakie Yakum, A. Pascal Goura; et al. (2019) CC

BMC Health Services Research (2019) 19:458 https://doi.org/10.1186/s12913-019-4315-7

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APCA Atlas of Palliative Care Africa

Rhee, J.Y.; et al. African Palliative Care Association (2020) C_WHO

The APCA Atlas provides the most up-to-date information of palliative care development in nearly all countries in Africa, using indicators derived, rated, and chosen by in-country African experts followed by a thorough Delphi consensus process with a panel of international experts on palliative care... more

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High Adherence Is Necessary to Realize Health Gains from Water Quality Interventions

Brown, J.; and T. Clasen (2012) CC

PlosOne May 7, 2012 https://doi.org/10.1371/journal.pone.0036735 ; Safe drinking water is critical for health. Household water treatment (HWT) has been recommended for improving access to potable water where existing sources are unsafe. Reports of low adherence to HWT may limit the usefulness of thi... more

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Pharmaceutical pollution of the world’s rivers

Wilkinson, J.L.; A.B. A. Boxall, D. W. Kolpin, et al. (2022) CC

PNAS 119 (8) e2113947119 | https://doi.org/10.1073/pnas.2113947119 Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, m... more

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Resource Effective Strategies to Prevent and Treat Cardiovascular Disease

Schwalm, J.; McKee, M.; Huffman, M. et al. Circulation (2016) CC

Cardiovascular disease (CVD) is the leading cause of global deaths, with the majority occurring in low- and middle-income countries (LMIC). The primary and secondary prevention of CVD is suboptimal throughout the world, but the evidence-practice gaps are much more pronounced in LMIC. Barriers at the... more

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Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes

Park, J.J. Diabetes & Metabolism Journal (2021) CC

The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients wit... more

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Quality of stroke guidelines in low- and middle-income countries: a systematic review

Yaria, J.; Gil, A.; Makanjuola, A. et al. Bulletin of the World Health Organization (2021) C_WHO

Objective: To identify gaps in national stroke guidelines that could be bridged to enhance the quality of stroke care services in low- and middle-income countries. Methods: We systematically searched medical databases and websites of medical societies and contacted international organizations. Co... more

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Optimal timing of HIV home‐based counselling and testing rounds in Western Kenya

Olney, Jack J.; Eaton, Jeffrey W.; Braitstein, Paula et al. (2018) CC

Journal of the International AIDS Society, vol. 21 Issue no. 6 e 25142
Weaknesses in care programmes providing anti‐retroviral therapy (ART) persist and are often instigated by late HIV diagnosis and poor linkage to care. We investigated the potential for a home‐based counselling and testin... more

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Tuberculosis and comorbidities in urban areas in Argentina. A gender and age perspective ,

Echazarreta, A.; Zerbini E. De Sandro j., et al. 2018 (2018) CC

180 Biomédica 2018;38:180-8

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HIV 2016/2017

C. Hoffmann und J. K. Rockstroh Medizin Fokus Verlag (2016) C2

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Child mental health in Sierra Leone: a survey and exploratory qualitative study

H.N.C. Yoder, W..Tol, R. Reis and J.T.V.M. deJong (2016) CC

This study complements the growing amount of research on the psychosocial impact of war on chil-dren in Sierra Leone by examining local perceptions of child mental health, formal and informal care systems, help-seeking behaviour and stigma Yoder et al. Int ... Ment Health Syst (2016) 10:48 DOI 10.1186/s13033-016-0080-8 more