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Medline Plus - Trusted Health Information for you - Website

Medline (2021) CC

Find information on health conditions, wellness issues, and more in easy-to-read language on MedlinePlus, the up-to-date, trusted health information site from the NIH and the National Library of Medicine.

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Health Videos Medline Plus

Medline Plus (2021) CC

These animated videos show the anatomy of body parts and organ systems and how diseases and conditions affect them.

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Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies

Alipanah N, Jarlsberg L et al. (2018) CC

We systematically reviewed Medline as well as the references of published review articles for relevant studies of adherence to multidrug treatment of both drug-susceptible and drug-resistant TB through February 3, 2018. We included randomized contro ... more

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A systematic examination of international funding flows for Ebola virus and Zika virus outbreaks 2014-2019: donors, recipients and funding purposes

Quirk, E.J.; A. Gheorghe; K. Hauck BMJ Global Health (2021) C1

There has been no systematic comparison of how the policy response to past infectious disease outbreaks and epidemics was funded. This study aims to collate and analyse funding for the Ebola epidemic and Zika outbreak between 2014 and 2019 in order to understand the shortcomings in funding reporting ... more

Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc ... e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Effectiveness of community health worker training programmes for cardiovascular disease management in low-income and middle-income countries: a systematic review

Abdel-All, M; Putica, B.; Praveen, D. et al. BMJ Open (2017) CC

Introduction Community health workers (CHWs) are increasingly being tasked to prevent and manage cardiovascular disease (CVD) and its risk factors in underserved populations in low-income and middle-income countries (LMICs); however, little is known about the required training necessary for them to ... more

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Green spaces and mortality: a systematic review and meta-analysis of cohort studies

Rojas-Rueda, D.; M.J. Nieuwenhuijsen, M. Gascon; et al. (2019) CC

Lancet Planet Health 2019; 3: 469–77

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Antibiotic stewardship interventions in hospitals in low-and middle-income countries: a systematic review

Van Dijck C., Vlieghe E., Cox J.A. Bulletin of the World Health Organization (2018) C_WHO

Objective: To review the effectiveness of antibiotic stewardship interventions in hospitals in low- and middle-income countries.

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Федеральные клинические рекомендации по диагностике и лечению болезни Альцгеймера

Колыхалов И.В. Министерство здравоохранения и социального развития РФ Федеральное государственное бюджетное учреждение «Научный центр психического здоровья» Российской академии медицинских наук (2013) C2

Доказательной базой для рекомендаций являются публикации, вошедшие в базы данных PubMed/MEDLINE, данные международных согласительных докуме� ... more

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Quality of the Indian clinical practice guidelines for the management of cardiovascular conditions

Dhurjati, R.; Sagar, V.; Kanukula, R. et al. Journal of the Royal Society of Medicine Open (2022) CC

To assess the quality of Indian clinical practice guidelines (CPG)s for the management of cardiovascular conditions, MEDLINE, Embase, Google Scholar and websites of relevant medical associations and government organisations were searched, from incep ... more

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Planetary health and the role of community health workers

Manas R. , Behera R., Satpathy S.K. J Family Med Prim Care (2020) C1

In this era, grand challenges lies in biodiversity loss, climate change, and global noncommunicable diseases signify that planet and humanity are in crisis. Scholarly evidence from human and animal kingdom suggest that there is an optimism in planetary health which can provide a unique and novel con ... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti ... ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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First Colombian consensus on congenital Chagas and clinical approach for women of child-bearing age diagnosed with Chagas

Cucunubá Z.M., Valencia-Hernándeza C.A. , Puerta C.J. et al (2017) C2

Congenital transmission of Chagas disease has not been extensively studied in Colombia, and there are no standardized processes in the health system regarding the specific diagnosis, treatment and follow-up of this disease. To generate recommendations on congenital Chagas disease and Chagas in wom ... more

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The link between the West African Ebola outbreak and health systems in Guinea, Liberia and Sierra Leone: a systematic review

Haitham Shoman, Emilie Karafillakis and Salman Rawaf (2017) CC

Shoman et al. Globalization and Health (2017) 13:1 DOI 10.1186/s12992-016-0224-2

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Restricting the use of antibiotics in food-producing animals and its associations with antibiotic resistance in food-producing animals and human beings: a systematic review and meta-analysis

K.L Tang, N.P Caffrey, D.B Nóbrega, et al. (2017) CC

Lancet Planet Health 2017 Published Online November 6, 2017 http://dx.doi.org/10.1016/S2542-5196(17)30141-9

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An estimate of the prevalence of epilepsy in Sub–Saharan Africa: A systematic analysis

Paul, A., Adeloye, D., George-Carey, et al. journal of Global health (2012) CC

www.jogh.org • doi: 10.7189/jogh.02.020405 ~ December 2012 • Vol. 2 No. 2 • 020405

Antivacinação: Um Movimento Consequente Na Realidade Brasileira

Rodrigues da Silva, M.; L. Aparecida de Souza Teles and E.G. da Silva Andrade (2020) C1

Rev Inic Cient e Ext. 2020; 3(2): 483-94; Trata-se de um estudo de revisão integrativa que tem como referencial teórico estudos de abordagem sindrômica dos problemas sobre a temática da recusa vacinal e o movimento antivacinação e os mitos que norteiam essa prática. Conclusão: O mo ... more