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Cardiovascular medicine and research in sub-Saharan Africa: challenges and opportunities

Zühlke, L.; Sliwa, K.; Naidoo, P. et al. Nature Reviews Cardiology (2019) CC

Africa is witnessing an epidemic of cardiovascular disease (CVD), with staggering morbidity and mortality. The spectrum of CVD includes hypertension, rheumatic heart disease, cardiomyopathy, atherosclerotic disease, congenital heart disease and tuberculous pericarditis. Opportunities exist to alter ... more

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Health Care Resource Utilization in Adults Living With Type 1 Diabetes Mellitus in the South African Public Health Sector: Protocol for a 1-Year Retrospective Analysis With a 5-, 10-, and 25-Year Pro

Bhana, S.; Naidoo, P.; Pillay, S.; et al. Jornal of Medical Internet Research JMIR Publication Published on 13.2.2023 in Vol 12 (2023) (2023) CC

Type 1 diabetes mellitus (T1DM) is less common than type 2 diabetes mellitus but is increasing in frequency in South Africa. It tends to affect younger individuals, and upon diagnosis, exogenous insulin is essential for survival. In South Africa, the health care system is divided into private and pu... more

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South African cardiovascular risk stratification guideline for non-cardiac surgery

Alphonsus, C.; Naidoo, N.; Motshabi, P. et al. South African Medical Journal (2021) CC

The South African (SA) guidelines for cardiac patients for non-cardiac surgery were developed to address the need for cardiac risk assessment and risk stratification for elective non-cardiac surgical patients in SA, and more broadly in Africa. The guidelines were developed by updating the Canadian ...Cardiovascular Society Guidelines on Perioperative Cardiac Risk Assessment and Management for Patients Who Undergo Non-cardiac Surgery, with a search of literature from African countries and recent publications. The updated proposed guidelines were then evaluated in a Delphi consensus process by SA anaesthesia and vascular surgical experts. The recommendations in these guidelines are: 1. We suggest that elective non-cardiac surgical patients who are 45 years and older with either a history of coronary artery disease, congestive cardiac failure, stroke or transient ischaemic attack, or vascular surgical patients 18 years or older with peripheral vascular disease require further preoperative risk stratification as their predicted 30-day major adverse cardiac event (MACE) risk exceeds 5% (conditional recommendation: moderate-quality evidence). 2. We do not recommend routine non-invasive testing for cardiovascular risk stratification prior to elective non-cardiac surgery in adults (strong recommendation: low-to-moderate-quality evidence). 3. We recommend that elective non-cardiac surgical patients who are 45 years and older with a history of coronary artery disease, or stroke or transient ischaemic attack, or congestive cardiac failure or vascular surgical patients 18 years or older with peripheral vascular disease should have preoperative natriuretic peptide (NP) screening (strong recommendation: high-quality evidence). 4. We recommend daily postoperative troponin measurements for 48 - 72 hours for non-cardiac surgical patients who are 45 years and older with a history of coronary artery disease, or stroke or transient ischaemic attack, or congestive cardiac failure or vascular surgical patients 18 years or older with peripheral vascular disease, i.e. (i) a baseline risk >5% for MACE 30 days after elective surgery (if no preoperative NP screening), or (ii) an elevated B-type natriuretic peptide (BNP)/N-terminal-prohormone B-type natriuretic peptide (NT-proBNP) measurement before elective surgery (defined as BNP >99 pg/mL or a NT-proBNP >300 pg/mL) (conditional recommendation: moderate-quality evidence). Additional recommendations are given for the management of myocardial injury after non-cardiac surgery (MINS) and medications for comorbidities. more

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Finding the Missing Tuberculosis Patients

D. P. Chin, C. L. Hanson The Journal of Infectious Disease; IDSA; Oxford, et al. (2017) C2

Supplement article The Journal of Infectious Diseases® 2017;216(S7):S675–8 DOI: 10.1093/infdis/jix368 Finding the Missing Tuberculosis Patients • JID 2017:216 (Suppl 7) • S675 Downloaded from https://academic.oup.com/jid/article-abstract/216/suppl_7/S675/4595547 by guest on 13 Nove... more

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Challenges in the diagnosis of asthma in children, what are the solutions? A scoping review of 3 countries in sub Saharan Africa

Magwenzi, P.; Rusakaniko, S.; Sibanda, E.N. et al. Respiratory Research (2022) CC

The article is a scoping review that explores the challenges in diagnosing asthma in children in three sub-Saharan African countries: Nigeria, South Africa, and Uganda. It identifies key barriers, such as a lack of community awareness, inadequate healthcare access, limited diagnostic tools like spir... more

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Barriers to childhood asthma care in sub-Saharan Africa: a multicountry qualitative study with children and their caregivers

Naidoo, K.L.; Dladla, S.; Mphahlele, R.E. et al. BMJ Open (2023) CC

This study identifies barriers and provides recommendations to improve asthma care in children across sub-Saharan Africa, where qualitative data is lacking despite high rates.

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Community health worker models in South Africa: a qualitative study on policy implementation of the 2018/19 revised framework

Murphy, J.P.; A. Moolla, S. Kgowedi et al. Health Policy and Planning (2020) C1

South Africa has a long history of community health workers (CHWs). It has been a journey that has required balancing constrained resources and competing priorities. CHWs form a bridge between communities and healthcare service provision within health facilities and act as the cornerstone of South A... more

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HIV prevalence and determinants of loss-to- follow-up in adolescents and young adults with tuberculosis in Cape Town

P. Mulongeni; S. Hermans; J. Caldwell; et al. PLOS One (2019) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0210937 February 5, 2019

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Recommandations pour les stratégies de dépistage et les capacités de diagnostic du SARS-CoV-2 à l’échelle nationale
recommended

World Health Organization WHO (2021) C_WHO

orientations provisoires, 25 juin 2021. Des tests de diagnostic rapides et précis sont un outil essentiel pour prévenir et contrôler la propagation du COVID-19. Ce document décrit les recommandations relatives aux stratégies nationales de dépistage et à l'utilisation de la PCR et des tests an... more

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Assessment of prison life of persons with disability in Ghana

Joslin Dogbe, Ellis Owusu-Dabo, Anthony Edusei et al. (2016) CC

BioMed Central; BMC International Health and Human Rights (2016) 16:20; DOI 10.1186/s12914-016-0094-y

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Cascada de atención de la tuberculosis para la población indígena en Colombia: una investigación operativa

Polanco-Pasaje JE, Rodríguez-Márquez I, Tello-Hoyos KY et al Revista Panamericana de Salud Pública (2018) CC

Esta investigacion construire y evalua la cascada de atención de la tuberculosis pulmonar en la población indígena del departamento del Cauca (Colombia) e identifica las brechas existentes. Este es el primer estudio en Colombia que analiza la cascada de atención de la TB en población indígena.... more

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Transforming Agriculture in Southern Africa

Sikora, R.A.; et al. Routledge (2020) CC

Constraints, Technologies, Policies and Processes

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BNF for Children 2019-2020

BMA; Royal Pharmaceutical Society, etal. (2020) C2

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Guidelines for antiretroviral therapy in HIV-1 infected adults and adolescents 2014, Thailand

Weerawat Manosuthi, Sumet Ongwandee, Sorakij Bhakeecheep et al. (2015)

AIDS Research and Therapy 2015, 12:12 (24 April 2015)

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World Report on Ageing and Health

John Beard, Alana Officer, Andrew Cassels et al. World Health Organization WHO (2015) C_WHO

Comprehensive public health action on population ageing is urgently needed. This will require fundamental shifts, not just in the things we do, but in how we think about ageing itself. The World report on ageing and health outlines a framework for action to foster Healthy Ageing built around the new... more

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Sentinel surveillance programme for hospitalised individuals with COVID-19 in South Africa

Jassat, W.; et al. (2020) CC

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Диагностика и лечение туберкулеза с множественной лекарственной устойчивостью возбудителя

Васильева Ирина Анатольевна, Самойлова Анастасия Геннадьевна, Эргешов Атаджан Эргешович et al. федеральное государственное бюджетное учреждение центральный научно-исследовательский институт туберкулеза российской академии медицинских наук, Американский международный союз здравоохранения (2012) C2

Cовершенствование теоретических знаний и практических навыков по вопросам диагностики и лечения туберкулеза с множественной лекарственной устойчивостью (МЛУ) ми... more

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Tuberculosis care cascade for the indigenous population in Colombia: an operational research study

Polanco-Pasaje, J.E.; Rodríguez-Márquez I. , Tello-Hoyos K. Y., et al. (2021) CC

Rev Panam Salud Publica 45, 2021 |

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Health worker migration from South Africa: causes, consequences and policy responses

Labonté et al Human Resources for Health (2015) CC

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Early versus late BCG vaccination in HIV-1- exposed infants in Uganda: study protocol for a randomized controlled trial

V. Nankabirwa , J. K. Tumwine, O. Namugga, et al. Trials; BooMed Central (2017) CC

Trials (2017) 18:152, DOI 10.1186/s13063-017-1881-z

Recommandations pour les stratégies de dépistage et les capacités de diagnostic du SARS-CoV-2 à l’échelle nationale recommended

Recommandations pour les stratégies de dépistage et les capacités de diagnostic du SARS-CoV-2 à l’échelle nationale
recommended