the aid library

New HIV testing technologies in the context of a concentrated epidemic and evolving HIV prevention (Yangon)

Wirtz, Andrea L.; Clouse, Emily; Veronese, Vanessa et al. (2017) CC

Journal of the International AIDS Society, Volume 20, Issue 1 (2017)21796
Qualitative research on HIV self testing among men who have sex with men and transgender women in Yangon, Mynamar.
Global effort to increase early diagnosis and engagement in HIV care emphasize the importance ... more

External Link

The expanding epidemic of HIV-1 in the Russian Federation

C. Beyrer; A. L. Wirtz; G. O’Hara; et al. PLOS Medicine (2017) CC

PLOS Medicine | https://doi.org/10.1371/journal.pmed.1002462 November 28, 2017

External Link

Access to Medications for Cardiovascular Diseases in Low- and Middle-Income Countries

Wirtz, V.J.; Kaplan, W.A.; Kwan, G.F. Circulation (2016) CC

Cardiovascular diseases (CVD) represent the highest burden of disease globally. Medicines are a critical intervention used to prevent and treat CVD. This review describes access to medication for CVD from ... health system perspective and strategies that have been used to promote access, including providing medicines at lower cost, improving medication supply, ensuring medicine quality, promoting appropriate use, and managing intellectual property issues. Using key evidence in published and gray literature and systematic reviews, we summarize advances in access to cardiovascular medicines using the 5 health system dimensions of access: availability, affordability, accessibility, acceptability, and quality of medicines. There are multiple barriers to access of CVD medicines, particularly in low- and middle-income countries. Low availability of CVD medicines has been reported in public and private healthcare facilities. When patients lack insurance and pay out of pocket to purchase medicines, medicines can be unaffordable. Accessibility and acceptability are low for medicines used in secondary prevention; increasing use is positively related to country income. Fixed-dose combinations have shown a positive effect on adherence and intermediate outcome measures such as blood pressure and cholesterol. We have a new opportunity to improve access to CVD medicines by using strategies such as efficient procurement of low-cost, quality-assured generic medicines, development of fixed-dose combination medicines, and promotion of adherence through insurance schemes that waive copayment for long-term medications. Monitoring progress at all levels, institutional, regional, national, and international, is vital to identifying gaps in access and implementing adequate policies. more

Download (168)

View PDF (192)

The Global HIV Epidemics among Sex Workers

D. Kerrigan; A. Wirtz; I. Semini; et al. The World Bank (2013) C2

Directions in Development Human Development

External Link

Financing HIV Programming: How Much Should Low And Middle-Income Countries and their Donors Pay?

Galarraga, O.; V. J. Wirtz; Y. Santa-Ana-Tellez et al. PLOS One (2013) C1

Global HIV control funding falls short of need. To maximize health outcomes, it is critical that national governments sustain reasonable commitments, and that international donor assistance be distributed according to country needs and funding gaps. We develop ... country classification framework in terms of actual versus expected national domestic funding, considering resource needs and donor financing. With UNAIDS and World Bank data, we examine domestic and donor HIV program funding in relation to need in 84 low- and middle-income countries. We estimate expected domestic contributions per person living with HIV (PLWH) as a function of per capita income, relative size of the health sector, and per capita foreign debt service. more

Download (151)

View PDF (222)

A prospective “test-and-treat” demonstration project among people who inject drugs in Vietnam

H. H. Nguyen; D. D. Bui; T. T.T. Dinh; et al. Journal of the International AIDS Society; PubMed.gov (2018) CC

Nguyen HH et al. Journal of the International AIDS Society 2018, 21:e25151 http://onlinelibrary.wiley.com/doi/10.1002/jia2.25151/full | https://doi.org/10.1002/jia2.25151

Download (133)

View PDF (170)

A four-step process for building sustainable access to diagnosis and treatment of Chagas disease

Batista, C.; Forsyth, C.; Herazo, F.; et al. Pan American Journal of Public Health (2019) CC

Over 6 million people worldwide are infected with Trypanosoma cruzi, the protozoan that causes Chagas disease (CD). T. cruzi is transmitted by triatomine insects, congenitally, through uncontrolled blood donations and organ transplants, and via consumption of food or drink contaminated by triatomi... more

Download (143)

View PDF (159)

Un long chemin reste à parcourir

ONUSIDA (2018) C2

Combler les écarts Rompre les barrières Réparer les injustices Synthèse

Download (154)

View PDF (152)

Assessment of a revolving drug fund for essential asthma medicines in Benin

Gildas Agodokpessi, Nadia Aït-Khaled, Martin Gninafon, Leon Tawo, Wilfried Bekou, Christophe Perrin, Karen Bissell, Nils Billo, Donald A Enarson, Chen-Yuan Chiang Journal of Pharmaceutical Policy and Practice (2015) C2

Agodokpessi et al. Journal of Pharmaceutical Policy and Practice (2015) 8:12DOI 10.1186/s40545-015-0033-7 Benin established a revolving drug fund (RDF) for essential asthma medicines in 2008. We evaluated the operation of the RDF and assessed wh... more

Download (470)

View PDF (1067)

Integrating collaborative TB and HIV services within a comprehensive package of care for people who inject drugs (Russian Version)

World Health Organization (2016) C_WHO

The END TB Strategy Интеграция совместного оказания услуг в связи с ТБ и ВИЧ во всеобъемлющий пакет помощи для потребителей инъекционных наркотиков

Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to... reduce antimicrobial overuse. A systematic evidence map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

External Link

Molecular and Clinical Aspects of Chronic Manifestations in Chagas Disease: A State-of-the-Art Review

Medina-Rincón, G.; Gallo-Bernal, S.; Jiménez, P.; et al. (2021) CC

Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493 .Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech... more

Download (123)

View PDF (165)

Increasing access to comprehensive care for Chagas disease: development of a patient-centered model in Colombia

Marchiol, A; Forsyth, C.; Bernal, O.; et al. Pan American Health Organization PAHO (2017) C_WHO

Rev. Panam Salud Publica. 2017;41:e153. doi: 10.26633/RPSP.2017.153 Worldwide, over 6 million people are infected with Trypanosoma cruzi, the pathogen that causes Chagas disease (CD). In the Americas, CD creates the greatest burden in disability-adjusted life years of any parasitic infection. In Co... more

External Link

Climate Change and Chagas Disease in the americas: A qualitative systematic review

Graves B.N. (2019) C2

Chagas disease is currently endemic and also predicted to be at increased transmission risk under future climate change scenarios. Similarly, an expansion of areas in the United States at increased risk for Chagas disease transmission is also expected over the next several decades under climate chan... more

External Link

Factors associated with HIV testing among young men who have sex with men in Myanmar: a cross‐sectional study

Minh D Pham; Poe Poe Aung; Aye Kyawt Paing et al. (2017) CC

Journal of the International AIDS Society 2017, vol. 20:e25026
In Myanmar, men who have sex with men (MSM) experience high risk of HIV infection. However, access to HIV testing and prevention services remains a challenge among this marginalized... more

External Link

Assessing changes in HIV-related legal and policy environments: Lessons learned from a multi-country evaluation

L. Ferguson; A. Nicholson; I. Henry; et al. PLOS One; US National Library of Medicine National Institutes of Health (PMC); NCBI (2018) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0192765 February 23, 2018

External Link

Availability, Affordability, Access, and Pricing of Anti-cancer Medicines in Low- and Middle-Income Countries: A Systematic Review of Literature

Ocran Mattila, P.; R. Ahmad, S.Shahzad Hasan, et al. (2021) C2

Front. Public Health, 30 April 2021 | https://doi.org/10.3389/fpubh.2021.628744

Ambient air pollution and non-communicable respiratory illness in sub-Saharan Africa: a systematic review of the literature

Glenn, B. E.; Espira, L. M.; Larson, M. C.; Larson, P. S. BMC (2022) CC2

Aerosol pollutants are known to raise the risk of development of non-communicable respiratory diseases (NCRDs) such as asthma, chronic bronchitis, chronic obstructive pulmonary disease, and allergic rhinitis. Sub-Saharan Africa’s rapid pace of urbanization, economic expansion, and population growt... more

External Link

Kazakhstan can achieve ambitious HIV targets despite expected donor withdrawal by combining improved ART procurement mechanisms with allocative and implementation efficiencies

A. J. Shattock; C. Benedikt; A. Bokazhanova; et al. PLOS One (2017) CC

Research Article PLOS ONE | DOI:10.1371/journal.pone.0169530 February 16, 2017

Download (154)

View PDF (202)

Biobehavioural Survey Guidelines - For Populations at risk for HIV

A. Abdul-Quader; M. Berry; T. Bingham; J. Burnett; et al. Centers for Diseases Control and Prevention; UNAIDS; World Health Organization; et al. (2017) C_WHO

Global HIV Strategic Information Working Group