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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more
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Melarsoprol Resistance in African Trypanosomiasis

Fairlamb, A.H.; Horn, D. Elsevier Ltd. (2018) CC
Arsenical monotherapies were previously very successful for treating human African trypanosomiasis (HAT). Melarsoprol resistance emerged as early as the 1970s and was widespread by the late 1990s. Melarsoprol resistance represents the only example of widespread drug resistance in HAT patients wher... more
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Full prescribing information Fexinidazole tablets, for oral use

Drugs for Neglected Diseases initiative DNDi (2021) C1
Full Perscribing information on Fexinidazole Tablet for oral use INDICATIONS AND USAGE Fexinidazole Tablets are indicated for the treatment of both the first-stage (hemolymphatic) and second-stage (meningoencephalitic) human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense in pati... more
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Knowledge, attitudes and practices about human African trypanosomiasis and their implications in designing intervention strategies for Yei county, South Sudan

Bukachi, SA.; Mumbo, AA.; Alak, ACD.; Sebit, W.; Rumunu, J. et al. PLOS Neclected Tropical Diseases (2018) CC
A clear understanding of the knowledge, attitudes and practices (KAP) of a particular community is necessary in order to improve control of human African trypanosomiasis (HAT).New screening and diagnostic tools and strategies were introduced into South Sudan, as part of integrated delivery of primar... more
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Earthquake response in Türkiye and Whole of Syria
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World Health Organisation (WHO) (2023) C_WHO
A 7.7 magnitude earthquake struck at 04:17 local time on 6 February 2023, with its epicentre located in Pazarcık district in Kahramanmaraş province, Türkiye. Over 1200 aftershocks have since been reported. These are Türkiye’ s most powerful earthquakes since 1939
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SYRIAN ARAB REPUBLIC response to earthquake: Situation report #3

World Health Organisation (WHO) (2023) C_WHO
In the early morning of 6 February 2023, a magnitude 7.8 earthquake struck southern Türkiye near the northern border of Syria. The earthquake was followed 11 minutes later by a magnitude 6.7 aftershock. Many aftershocks continue to be felt across the region. Whilst the impact is still being ass... more
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Surveillance, prevention and control of leishmaniases in the European Union and its neighbouring countries

European Centre for disease prevention and control (ECDC) European Centre for disease prevention and control (ECDC) (2022) C_CDC
This technical report presents the epidemiology of human and animal leishmaniases in the EU and its neighbouring countries and concludes that the disease remains widespread and underreported in many countries of southern Europe, northern Africa, and the Middle East and that there is a need to improv... more
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UNFPA Regional Response to Ukraine Emergency. Situation Report #16. 17 February 2023

United Nations Population Fund (UNFPA) (2023) C1
NFPA continues to work with partners to respond to the Ukraine emergency. Highlights from the month of January include: - The #TrainOfHope launched between Kyiv and Chisinau is a lifeline, providing refugees, including many women with children, both a route to safety and a way back home. - When t... more
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Interregional meeting on leishmaniasis among neighbouring endemic countries in the Eastern Mediterranean, African and European regions

World Health Organization WHO (2019) C_WHO
An interregional meeting on leishmaniasis among neighbouring endemic countries in the Eastern Mediterranean, African and European regions was organized by the World Health Organization (WHO) Regional Office for the Eastern Mediterranean in Amman, Jordan, from 23 to 25 September 2018. The meeting w... more
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Stratégie de riposte face à la résistance aux antipaludiques en Afrique

World Health Organisation (WHO) (2023) C_WHO
La Stratégie de riposte face à la résistance aux antipaludiques en Afrique est un document technique de sensibilisation qui se fonde sur les bases factuelles les plus solides dont on dispose et vise à réduire au maximum la menace et l’impact de la résistance aux antipaludiques de Plasmodium ... more
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Soins d’avortement sans risque pendant les épidémies de maladies infectieuses

Inter-agency Working Group on Reproductive Health in CrisesInternational Rescue Committee (2023) CC
Ce guide a pour objectif de fournir des conseils pratiques à destination du personnel de santé entreprenant des activités de préparation et de réponse aux maladies infectieuses afin de maintenir l’accès à des Soins d’Avortement sans Risque (SAR) durant une épidémie de maladie infectieus... more
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Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming

Williams, D.; Faiz, M.; Abela-Ridder, B. et al. PLoS Neglected Tropical diseases (2019) CC
In one of his final essays, statesman and former United Nations secretary general Kofi Annan said, ‘Snakebite is the most important tropical disease you’ve never heard of’. Mr. Annan firmly believed that victims of snakebite envenoming should be recognised and afforded greater efforts at impro... more
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Standard Treatment Guidline: Management of Snake Bite

Ministry of Health and Family Welfare - Government of India (2016) CC
Snakebite is an acute life threatening time limiting medical emergency. It is a preventable public health hazard often faced by rural population in tropical and subtropical countries with heavy rainfall and humid climate.
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Consulta técnica regional OPS/MSF sobre Organización y estructura de la atención médica del enfermo o infectado por Trypanosoma cruzi (enfermedad de Chagas)

Organización Panamericana de la Salud (2005) C2
El desarrollo, desde 1991, de las Iniciativas Subregionales de Control de la Enfermedad de Chagas, y los avances de conocimiento en materia de diagnóstico y manejo de la infección/enfermedad de Chagas, llevan a la necesidad ética, y operativamente imperiosa, de estructurar el diagnóstico, atenci... more
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Infection prevention and control in the context of coronavirus disease (‎COVID-19)‎: a living guideline, 13 January 2023

World Health Organisation (WHO) (2023) C_WHO
The WHO continuously reviews available data on SARS-CoV-2 variants of concern. For this version, the global epidemiological situation of the COVID-19 pandemic as of 21 January 2022 – at a time when the Omicron VOC had been identified in 171 countries across all six WHO Regions and was rapidly re... more
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A – Z of Rabies – A guide to the world´s deadliest disease

Mission Rabies (2023) C2
Accessed on 07.03.2023 A – Z of Rabies – A guide to the world´s deadliest disease Mission Rabies
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Rabies vaccines and immunoglobulins: WHO position

World Health Organization WHO (2017) C_WHO
The new WHO recommendations for rabies immunization supersede the 2010 WHO position on pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) for rabies. These updated recommendations are based on new evidence and directed by public health needs that are cost-, dose- and time-sparing... more
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A Guide to World Food Safety Day 2023

World Health Organisation (WHO) (2023) C_WHO
The fifth World Food Safety Day (WFSD) will be celebrated on 7 June 2023 to draw attention and inspire action to help prevent, detect and manage foodborne risks, contributing to food security, human health, economic prosperity, agricultural production, market access, tourism and sustainable developm... more
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WHO Guide for Rabies Pre and Post Exposure Prophylaxis in Humans

World Health Organization WHO (2014) C_WHO
WHO strongly recommends discontinuation of the nerve tissue vaccine, and replacement with modern concentrated and purified cell culture derived vaccines (CCDV) and embryonated eggbased rabies vaccines. These vaccines must comply with WHO criteria for potency and innocuity following satisfactory ass... more
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Estudios de vigilancia centinela de la resistencia adquirida por el VIH contra el dolutegravir en personas tratadas con este antirretrovírico en un esquema combinado

World Health Organisation (WHO) (2023) C_WHO
A medida que el tratamiento antirretrovírico con dolutegravir se extiende a más personas que viven con el VIH en el mundo, adquiere más importancia estimar la frecuencia con que surge la farmacorresistencia adquirida a este antirretrovírico en las poblaciones tratadas con esquemas que lo conti... more