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Analysis of Pandemic Preparedness and Response (PPR) architecture, financing needs, gaps and mechanisms

World Bank (2022) CC

A global Pandemic, Preparedness and Response (RRR) architecture

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Africa CDC Reproductive Health | Strategic Priorities 2022-2026

Centers for Disease Control and Prevention (CDC) (2023) CC

In 2006, the Special Session of African Union Health Ministers adopted the Maputo Plan of Action for implementing the Continental Policy Framework on sexual and reproductive health and rights (SRHR), which expired at the end of 2015. The goal was for all stakeholders and partners to join forces and ... more

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Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward

Minja, N.W.; Nakagaayi, D.; Aliku, T. et al. Frontiers in Cardiovascular Medicine (2022) CC

In 2015, the United Nations set important targets to reduce premature cardiovascular disease (CVD) deaths by 33% by 2030. Africa disproportionately bears the brunt of CVD burden and has one of the highest risks of dying from non-communicable diseases (NCDs) worldwide. There is currently an epide...miological transition on the continent, where NCDs is projected to outpace communicable diseases within the current decade. Unchecked increases in CVD risk factors have contributed to the growing burden of three major CVDs—hypertension, cardiomyopathies, and atherosclerotic diseasesleading to devastating rates of stroke and heart failure. The highest age standardized disability-adjusted life years (DALYs) due to hypertensive heart disease (HHD) were recorded in Africa. The contributory causes of heart failure are changing—whilst HHD and cardiomyopathies still dominate, ischemic heart disease is rapidly becoming a significant contributor, whilst rheumatic heart disease (RHD) has shown a gradual decline. In a continent where health systems are traditionally geared toward addressing communicable diseases, several gaps exist to adequately meet the growing demand imposed by CVDs. Among these, high-quality research to inform interventions, underfunded health systems with high out-of-pocket costs, limited accessibility and affordability of essential medicines, CVD preventive services, and skill shortages. Overall, the African continent progress toward a third reduction in premature mortality come 2030 is lagging behind. More can be done in the arena of effective policy implementation for risk factor reduction and CVD prevention, increasing health financing and focusing on strengthening primary health care services for prevention and treatment of CVDs, whilst ensuring availability and affordability of quality medicines. Further, investing in systematic country data collection and research outputs will improve the accuracy of the burden of disease data and inform policy adoption on interventions. This review summarizes the current CVD burden, important gaps in cardiovascular medicine in Africa, and further highlights priority areas where efforts could be intensified in the next decade with potential to improve the current rate of progress toward achieving a 33% reduction in CVD mortality. more

Guidelines for the management of asthma in adults and adolescents: Position statement of the South African Thoracic Society – 2021 update

Lalloo, U.G.; Kalla, I.S.; Abdool-Gaffar, S. et al. African Journal of Thoracic and Critical Care Medicine (2021) CC

sthma prevalence is increasing worldwide, and surveys indicate that most patients in developed and developing countries, including South Africa, do not receive optimal care and are therefore not well controlled. Standard management guidelines adapted to in-country realities are important to support ... more

Mpox Continental Preparedness and Response Plan for Africa
recommended

World Health Organisation (WHO) (2024) C_WHO

On August 13, 2024, the Africa CDC declared the mpox outbreak a Public Health Emergency of Continental Security (PHECS). The following day, the WHO declared it a Public Health Emergency of International Concern (PHEIC). A coordinated, continent-wide response is essential, co-led by the African Union... more

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Neglected Tropical Diseases and their Control in Uganda

Jan H. Kolaczinski, et al. Malaria Consortium (2006) C1

Situation Analaysis and Needs Assessment

Manuel de formation des realis communautaires en santé maternelle et neonatale et en technqiues de communication, Haiti

Mwangaza Action, aware, UNICEF, USAID (2008) CC

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Cameroon: PLAN STRATEGIQUE NATIONAL DE LUTTE CONTRE LE VIH, LE SIDA ET LES IST 2014 - 2017

REPUBLIQUE DU CAMEROUN, MINISTERE DE LA SANTE PUBLIQUE, COMITE NATIONAL DE LUTTE CONTRE LE SIDA, GROUPE TECHNIQUE CENTRAL (2013) C1

Antibiotic Guidelines 2015-2016

John Hopkins Hospital antimicrobioal Stewardship Program (2015) C1

Treatment Recommendations for Adult Inpatients

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Nigeria: National Quality Assurance Policy For Medicines and Other Health Products

Federal Ministry of Health, Nigeria (2015) C1

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Uganda: Mid Term Review of the 2010 – 2015 Malaria Strategic Plan

Ministry of Health, Uganda (2014) C1

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India: Uphold My Reproductive Rights

UNFPA; Ministry of Health and Family Welfare, Government of India; National Human Rights Commission (2016) C1

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Antimicrobial Resistance. Aide memoire

World Health Organization WHO; FAO (2016) C_WHO

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DRC: Guide de prise en charge des épidémies dans une zone de santé: Rougeole

Direction de Lutte contre la Maladie, Ministère de la Santé Publique, RD du Congo (2012) C1

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24 martie - Ziua mondială de luptă împotriva Tuberculozei

Institutul de Pneumoftiziologie ”Marius nasta” (2017) C2

Comunicat de presă Accessed December 2017

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Enquête sur la Prestation des Services de Soins de Santé au Rwanda 2007 Document de synthèse

Institut National de la Statistique - INSRwanda, Ministère de la Santé - MINISANTÉ (2008) C2

L’Enquête sur la Prestation des services de Santé du Rwanda de 2007 (EPSR) décrit comment le secteur formel de la santé du Rwanda fournit les servicesde planification familiale, de santé maternelle et infantile, de paludisme, de VIH/sida et d’autres maladies transmissibles.

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Approaches for mobile and migrant populations in the context of malaria multi-drug resistance and malaria elimination in the Greater Mekong Subregion

World Health Organization ( WHO), Regional Oﬃce for South-East-Asia (2016) C_WHO

The emergence of multifrug-resistant malaria in the Greater Mekong Subregion (‎GMS)‎ has been identified as an emergency issue that may have catastrophic consequences on the future of malaria elimination in the GMS as well as globally. In recognition of the need for a cohesive regional response,... more

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WHO guideline on health policy and system support to optimize community health worker programmes. Selected highlights
recommended

World Health Organization WHO (2018) C_WHO

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Standard Operating procedures for Immunophenotyping of Hematolymphoid Neoplasms

Indian Council of Medical Research (ICMR) (2016) C1

Prepared as an outcome of ICMR Expert Group on Immunophenotyping of Hematolymphoid Neoplasms | Coordinated by Division of Non Communicable Diseases | This document addresses on various issue related to good quality practices in laboratory work up of flow cytometric immunophenotyping and will be of u... more

Mpox Continental Preparedness and Response Plan for Africa recommended

WHO guideline on health policy and system support to optimize community health worker programmes. Selected highlights recommended

Mpox Continental Preparedness and Response Plan for Africa
recommended

WHO guideline on health policy and system support to optimize community health worker programmes. Selected highlights
recommended