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WHO policy guidance on integrated antimicrobial stewardship activities. Online Course

World Health Organization WHO (2022) C_WHO

Member States have requested WHO policy guidance on how to facilitate the implementation of national AMS activities in an integrated and programmatic approach. This policy guidance responds to that demand from Member States and is anchored in public health guiding principles in the human health sect... more

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Report of the 4TH Global Scientific Meeting on Trachoma

World Health Organization WHO (2018) C_WHO

Trachoma is the leading infectious cause of blindness (2). It is characterized by repeated conjunctival infection with particular strains of Chlamydia trachomatis. This scars the conjunctivae and, in some cases, leads to trichiasis with or without entropion. The abrasive action of eyelashes can d... more

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Manuals, guidelines and toolkits to support the elimination of blinding trachoma

Courtright, P.; MacArthur, C. International Trachoma Initative iTi (2015) CC

The year 2020 is the target date for the elimination of blinding trachoma as a public health problem. There has been great progress, and there is unprecedented funding available – particularly from DFID, the Queen Elizabeth Diamond Jubilee Trust, and USAID. There is also reason for optimism that, ... more

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Chagas disease key facts

International Federation of Red Cross and Red Crescent Societies IFRC IFRC (2022) C1

About six to seven million people worldwide, mostly in Latin America, are estimated to be infected with Trypanosoma cruzi, the parasite that causes Chagas disease (WHO data from 2021). Chagas disease is found mainly in endemic areas of 21 Latin American countries. Chagas disease was once entirely ... more

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Environmental Stewardship and Climate Action Handbook

World Vision (2023) CC

Climate change presents the single biggest threat to human development, and its widespread impacts disproportionately burden the poorest and most vulnerable households in fragile and rural developing contexts – particularly women and children. According to the Intergovernmental Panel on Climate C... more

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Vector alert: Anopheles stephensi invasion and spread in Africa and Sri Lanka

World Health Organization WHO (2023) C_WHO

Anopheles stephensi, a highly competent vector of Plasmodium falciparum and P. vivax, is considered an efficient vector of urban malaria. Until 2011, the reported distribution of An. stephensi was confined to certain countries of South Asia and parts of the Arabian Peninsula. Since then, the vector ... more

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Fexinidazole for T.b. gambiense (Sleeping Sickness)

Drugs for Neglected Diseases initiative DNDi (2022) C2

DNDi is now striving to make fexinidazole available to the majority of people who have T.b. gambiense sleeping sickness. We are supporting a three-year access and pharmacovigilance study that began in 2020 and have so far carried out in-country training of relevant staff in 250 hospitals and... more

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The new WHO guideline for control and elimination of human schistosomiasis: implications for the Schistosomiasis Elimination Programme in Nigeria

Akinola Stephen Oluwole, Uwem Friday Ekpo, Obiageli Josephine Nebe et al. Infectious Diseases of Poverty (2022) CC

With some 134,073,166 people living in endemic communities at risk of infection, Nigeria is the most endemic country in Africa and requires preventive chemotherapy (PC) for a total of 26.3 million persons. The National Schistosomiasis Elimination Programme (NSCHEP), with the support of international... more

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Dracunculiasis

Rawla, P.; Jan, A. National Library of Medicine (2022) CC

Dracunculiasis, also known as Guinea-worm disease is a parasitic disease caused by the nematode Dracunculus medinensis. The infection is transmitted to humans by drinking water contaminated with the small crustacean copepods (Cyclops) which contain the larvae of D. medinensis. Humans are the princip... more

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Diagnosis and Clinical Management of Chagas Disease: An Increasing Challenge in Non-Endemic Areas

Suárez, C., Nolder, D., García-Mingo, A. et al. Research and reports in tropical medicine (2022) CC

Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central, South America, Mexico and the South of the United States. It is an important cause of early mortality and morbidity, and it is associated with poverty and stigma. A third of the cases evolve into chronic... more

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Epidemiology of Chagas disease in pregnant women and congenital transmission of Trypanosoma cruzi in the Americas: systematic review and meta-analysis

Santana, K.; Oliveira, L.; Barros de Castro, D. et al. Tropical medicine & international health (2020) CC

Objective To estimate the prevalence of Chagas disease in pregnant women and the vertical transmission of the disease. Methods Observational studies were identified from eight electronic databases, and details on study design, population and prevalence of Chagas disease were extracted. The data... more

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Impacts of the Russia-Ukraine War on Global Food Security: Towards More Sustainable and Resilient Food Systems?

Ben Hassen, T.; El Bilali, H. (2022) CC

As a conflict between two major agricultural powers, the Russia–Ukraine war has various negative socioeconomic impacts that are now being felt internationally and might worsen, notably, for global food security. If the war deepens, the food crisis will worsen, posing a challenge to many countries,... more

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Yaws: International Journal of STD & AIDS

Marks, M.; Lebari, D.; Higgins,S. et al. International Journal of STD & AIDS (2014) CC

Yaws is a non-venereal endemic treponemal infection caused by Treponema pallidum sub-species pertenue, a bacterium closely related to Treponema pallidum ssp. pallidum, the agent of venereal syphilis. Yaws predominantly affects children living in tropical regions of the world. It causes lesions of th... more

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Easy Read: Gender Disability Sexual and Reproductive Health and Rights Checklist during Covid-19

United Nations Population Fund UNFPA (2023) CC

Making sure that people with disabilities get the right health care to do with their bodies, sex, relationships and having children during COVID-19 About this information This information is about health care for people with disabilities to do with their bodies, sex, relationships and having c... more

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Clinical management of COVID-19: living guideline, 13 January 2023

World Health Organisation (WHO) (2023) C_WHO

As of 12 December 2022, over 645 million people worldwide have been diagnosed with COVID-19, with over 6.6 million deaths (4). The Omicron variant, which emerged in late November 2021, and its subvariants, are now the dominant circulating viruses, contributing to the ongoing surge in several countr... more

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Education and Community Engagement is integral to our mass Vaccination Projects

Mission Rabies (2023) CC

Children are at high risk of dog bites and contracting rabies. Forty percent of reported rabies cases worldwide are children under the age of fifteen. In our project areas, the proportion of children dying is often even higher. Rabies most often persists in poor communities and rural regions of deve... more

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African regional progress and status of the programme to eliminate lymphatic filariasis: 2000–2020

Deribe K., Bakajikaa D. K., Zourea H. MG. et al The royal society of tropical medicine and hygiene (2021) C2

To eliminate lymphatic filariasis (LF) by 2020, the World Health Organization (WHO) has launched a campaign against the disease. Since the launch in 2000, significant progress has been made to achieve this ambitious goal. In this article we review the progress and status of the LF programme in Afric... more

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Praziquantel for the treatment of schistosomiasis during human pregnancy

Friedman, J.F. et al. (2018) CC

In 2014, an estimated 40 million women of reproductive age were infected with Schistosoma haematobium, S. japonicum and/or S. mansoni. In both 2003 and 2006, the World Health Organization (WHO) recommended that all schistosome-infected pregnant and breastfeeding women be offered treatment, with praz... more

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Rethinking the Top-Down Approach to Schistosomiasis Control and Elimination in Sub-Saharan Africa

Onasanya A. et al. (2021) CC

The control and elimination of schistosomiasis have over the last two decades involved several strategies, with the current strategy by the World Health Organization (WHO) focusing mainly on treatment with praziquantel during mass drug administration (MDA). However, the disease context is complex wi... more

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Preventing Child and Maternal Deaths: A Framework for Action in a Changing World 2023-2030

US Agency for International Development USAID (2023) CC

Improving the survival chances and quality of life of women, newborns, and children remains an urgent global challenge. Since 2012, substantial progress has been made in reducing maternal and under-5 deaths, and a only handful of countries are on target to meet the SDG targets in 2030. Yet, 5 millio... more