the aid library

Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

Ana Maria Henao-Restrepo, Ira M Longini, Matthias Egger, et al. (2015)

the Lancet : Published Online July 31, 2015 http://dx.doi.org/10.1016/S0140-6736(15)61117-5

Identification and management of Guillain-Barré syndrome in the context of Zika virus

World Health Organization WHO (2016) C_WHO

Updated 22 august 2016. This document aims to provide interim guidance on the case definition of GBS and strategies to manage the syndrome, in the context of Zika virus and its potential association with GBS. This document is intended to inform the development of local clinical protocols and health ... more

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

Henao-Restrepo, A.M.; et al. (2016)

The Lancet. Published Online December 22, 2016 http://dx.doi.org/10.1016/S0140-6736(16)32621-6. Open Access

Plague Outbreak Madagascar. External Situation Report. Report 10 14 November 2017

World Health Organization WHO (2017) C_WHO

Tuberculosis in the Americas - Regional Report 2015

World Health Organization; Pan American Health Organization (2015) C_WHO

Epidemiology, Control, and Financing

Zambia: Cholera Outbreak Lusaka - Emergency Plan of Action Operation n° MDRZM011

International Federation of Red Cross And Red Crescent Societies (2018) C1

Nigeria: Preparedness and Response to Acute Watery Diarrhoea Outbreaks

Federal Ministry of Health - Nigeria Centre for Disease Control (2017) C2

A GUIDE FOR HEALTH WORKERS AND AUTHORITIES IN NIGERIA

Vaccination in Acute Humanitarian Emergencies - A Framework for Decision Making
recommended

World Health Organization (2018) CC

Humanitarian emergencies, regardless of type and cause, have a number of common risk factors for communicable diseases inextricably linked to excess risk of morbidity and mortality which can come from vaccine–preventable diseases (VPDs). The reduction of VPDs is a significant aim of public-health ... more

National Primary Health Care Development Agency: Preparedness and response to coronavirus disease 2019 (COVID-19) at primary healthcare and community level
recommended

Government of Nigeria (2020) C1

This document sets out the preparedness and response plan of the Nigerian Primary Health Care System for COVID-19 Acute Respiratory Disease. It outlines the planning scenarios, key areas of work and priority activities required for the Primary Health Care Sector to quickly scale up its core capacity ... more

National Comprehensive Covid19 Management Handbook First Edition 2020

Ministry of Health, Federal Democratic Republic of Ethiopia Ministry of Health, Federal Democratic Republic of Ethiopia (2020) C1

Cognizant of the need for standardization of the response for COVID-19, the Federal Ministry of Health prepared this national guideline in an effort to contain the epidemic before it overwhelms the health care facilities. This national guideline is expected to guide policy makers and h ... more

The burden of HIV and tuberculosis on the resuscitation area of an urban district-level hospital in Cape Town

Swarts, L.; S. Lahri, and D.J. van Hoving (2021) CC

African Journal of Emergency Medicine Volume 11, Issue 1, March 2021, Pages 165-170

Rabies epidemiology, prevention and control in Nigeria: Scoping progress towards elimination

Mshelbwala, P.; Weese, J.; Sanni-Adeniyi, O. et al. PLoS Neglected Tropical diseases (2021) CC

Human rabies remains a significant public health problem in Africa with outbreaks reported in most countries. In Nigeria–the most populous country in Africa–rabies causes a significant public health burden partly due to perennial obstacles to implementing a national prevention and control progra ... more

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde ... d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Management of Tuberculosis: A Guide to the Essentials of Good Clinical Practice
recommended

International Union Against Tuberculosis and Lung Disease (2019) C1

The 7th edition of the Orange Guide provides practical guidance to health workers on the front line of TB control. It includes sections on HIV, MDR-TB and a review of the recommended treatment regimens

European guideline on the management of syphilis

M. Janier, V. Hegyi, N. Dupin et al (2014)

J. European Academy of Dermatology and Venereology, 4 August 2014

Clinical management of patients in the Ebola Treatment Centres and other care centres in Sierra Leone

Ministry of Health and Sanitation Sierra Leone; World Health Organization (2015)

Interim emergency guidelines

Philippines: Leptospirosis Guidelines
recommended

Manolito L. Chua, Marissa M. Alejandria Philippine Society for Microbiology and Infectious Diseases (2010) C1

The use of loop-mediated isothermal amplification (TB-LAMP) for the diagnosis of pulmonary tuberculosis: policy guidance

World Health Organization WHO (2016) C_WHO

Following review of the latest evidence, WHO recommends that TB-LAMP can be used as a replacement for microscopy for the diagnosis of pulmonary TB in adults with signs and symptoms of TB. It can also be considered as a follow-on test to microscopy in adults with signs and symptoms of pulmonary TB, e ... more

Guidelines on the Management of Sexually‐Transmitted Infections (STI) In Pregnancy

National Center for Disease Prevention and Control Department of Health, Philippines (2010) C1