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Clinical Presentation of T.b. rhodesiense Sleeping Sickness in Second Stage Patients from Tanzania and Uganda

Kuepfer, I.; Hhary, EP.; Mpairwe, A.; Edielu, A.; Burri, C.; Blum, JA. PLOS Neglected Tropical Diseases (2011) CC
A wide spectrum of disease severity has been described for Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense (T.b. rhodesiense), ranging from chronic ... patterns in southern countries of East Africa to an increase in virulence towards the north. However, only limited data on the clinical presentation of T.b. rhodesiense HAT is available. From 2006-2009 we conducted the first clinical trial program (I MPAMEL III) in T.b. rhodesiense endemic areas of Tanzania and Uganda in accordance with international standards (ICH-GCP). The primary and secondary outcome measures were safety and efficacy of an abridged melarsoprol schedule for treatment of second stage disease. Based on diagnostic findings and clinical examinations at baseline we describe the clinical presentation of T.b. rhodesiense HAT in second stage patients from two distinct geographical settings in East Africa. more
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Serious adverse events following treatment of visceral leishmaniasis: A systematic review and meta-analysis

Singh-Phulgenda, S., Dahal, P., Ngu, R. et al. PLOS Neglected Tropical Diseases (2021) C1
Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review ... all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported serious adverse events (SAEs). more
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Risk factors of Cholera mortality

Global Task Force On Cholera Control (GTFCC) (2022) CC
To better adapt current case management practices and address excess mortality in otherwise treatable cases will require better knowledge of the demographic characteristics of the patients and como... more
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National Guidelines for HIV and AIDS Treatment and Care in Adolescents and Adults

Federal Ministry of Health Nigeria , World Health Organisation (WHO) (2010) C_WHO
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India: Guidelines on Airborne Infection Control in Healthcare and Other Settings

Directorate General of Health Services , Ministry of Health & Family Welfare, Government of India (2010) C1
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National Eye Care Strategic Plan 2011-2016

Ministry of Health and Social Welfare, Tanzania (2011) CC
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Mali: Ebola virus disease preparedness EPOA: Final Report Operation n° MDRML010

International Federation of Red Cross and Red Crescent Societies; (2015)
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National Village Health Teams (VHT) Assessment in Uganda

Ministry of Health, Republic of Uganda (2015) C1
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National Guidelines for PMTCT, peer education and psychosocial support in Kenya

The Kenya Mentor Mother Program Ministry of Health (2012) C1
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Infection Control Assessment Tool
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USAID; Managment of Health Sciences MSH (2009) C1
Strengthening Parmaceutical Systems. 2nd edition