the aid library

Bridging the gap between ethics and decision-making in pandemics - Report of the WHO Pandemic Ethics and Policy Summit

World Health Organization WHO OCHA Services reliefweb (2022) C_WHO

The COVID-19 pandemic has raised profound ethical challenges on an unprecedented global scale. These challenges include how to allocate scarce resources (especially vaccines and therapeutics), both within and between countries, whether and when to mandate vaccines and/or masks, whether and how to co... more

The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data plat

Maguire, B.J.; Dahal, P.; Rashan, S. et al. PLOS Neglected Tropical Diseases (2021) CC

PLoS Negl Trop Dis 15(8): e0009697. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses t... more

Report of the first WHO stakeholders meeting on gambiense human African trypanosomiasis elimination

World Health Organization WHO (2014) C_WHO

The objectives of the meeting were: 1. To step up the commitment of national authorities and technical and financial partners toWHO’s elimination objective for g-HAT. 2. To share achievements, challenges and views on the elimination goal among countries and implementing partners. 3. To assess t... more

Clinical management of COVID-19: living guideline, 13 January 2023

World Health Organisation (WHO) (2023) C_WHO

As of 12 December 2022, over 645 million people worldwide have been diagnosed with COVID-19, with over 6.6 million deaths (4). The Omicron variant, which emerged in late November 2021, and its subvariants, are now the dominant circulating viruses, contributing to the ongoing surge in several countr... more

Water dilemmas: The cascading impacts of water insecurity in a heating world

Oxfam (2023) CC

Climate-induced water insecurity poses one of the biggest threats to humanity and will lead to more hunger, disease and displacement Oxfam water engineers are having to drill deeper, more expensive and harder-to-maintain water boreholes used by some of the poorest communities around the world, mo... more

The Global Burden of Disease Study at 30 years

Murray, C.J.L. nature medicine (2022) CC

The Global Burden of Disease Study (GBD) began 30 years ago with the goal of providing timely, valid and relevant assessments of critical health outcomes. Over this period, the GBD has become progressively more granular. The latest iteration provides assessments of thousands of outcomes for diseases... more

Medicinal Plants in Papua New Guinea

World Health Organization (WHO), Regional Office for the Western Pacific (2009) C_WHO

Traditional medicine, including the knowledge, skills and practices of holistic health care, exists in all cultures. It is based on indigenous theories, beliefs and experiences and is widely accepted for its role in health maintenance and the treatment of disease.Medicinal plants are the main ingred... more

Kangaroo mother care: a transformative innovation in health care

World Health Organisation (WHO) (2023) C_WHO

This document puts forward the joint position and vision of an expert, global, multistakeholder working group on implementing Kangaroo Mother Care (KMC) for all preterm or low birth weight (LBW) infants as the foundation for small and/or sick newborn care within maternal, newborn, and child health p... more

A Roadmap to combat postpartum haemorrhage between 2023 and 2030

World Health Organization WHO (2023) C_WHO

WHO today released its first roadmap to tackle postpartum haemorrhage (PPH) – defined as excessive bleeding after childbirth - which affects millions of women annually and is the world’s leading cause of maternal deaths. Despite being preventable and treatable, PPH results in around 70 000 de... more

Antibacterial agents in preclinical development: an open access database

World Health Organization WHO (2019) C_WHO

The pre-clinical pipeline shows more innovation and diversity, with 252 agents being developed to treat WHO priority pathogens. However, these products are in the very early stages of development and still need to be proven effective and safe. The optimistic scenario, the report indicates, is for... more

COVID Reference 2021.6 EN
recommended

Kamps, B.S.; Camp, R. and C. Hoffmann (2021) CC

Ethical considerations in HIV prevention trials

World Health Organization WHO; UNAIDS (2021) C_WHO

UNAIDS and the World Health Organization have published this updated guidance on ethical considerations in HIV prevention trials. The new guidance is the result of a year-long process that saw more than 80 experts and members of the public give inputs and is published 21 years after the first editio... more

How do vaccines work?

World Health Organization WHO (2021) C_WHO

This article is part four in a series of explainers on vaccine development and distribution Available in different languages

How are vaccines developed?

World Health Organization WHO (2021) C_WHO

This article is part two in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. This article focuses on the ingredients in a vaccine and the three clinical trial phases. Part three outlines the nex... more

How a few poorly designed COVID-19 studies may have contributed to misinformation in Brazil: the case for evidence-based communication of science

Lucena Alves, C.P. de; J.de D. Barreto Segundo, G.Gonçalves da Costa, et al. (2022) CC

BMJ Open Science 2021;5:e100202. doi:10.1136/ bmjos-2021-100202

Field Trials of Health Interventions: A Toolbox

Peter G. Smith, Richard H. Morrow, and David A. Ross (2015)

This version of Field Trials of Health Interventions includes seven new chapters on conducting systematic literature reviews, trial governance, preliminary studies and pilot testing, budgeting and accounting, intervention costing and economic analysis, and Phase IV studies. Before new interventions... more