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2
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Planning for public health emergencies should ensure that capabilities developed during previous emergencies are maintained, incorporated, and put into practice when a new event of public health concern arises. Investments in pandemic preparedness lead to more rapid detection and a stronger
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response to public health threats, thereby shielding communities from the debilitating social and economic effects of epidemics and pandemics. The Pan American Health Organization (PAHO) recognizes the efforts of countries in the Region of the Americas to develop and/or strengthen their respiratory pathogen pandemic plans. PAHO supports planning activities with tools and expertise, aligning these efforts with the Preparedness and Resilience for Emerging Threats (PRET) initiative. The PRET initiative is an innovative approach to improving disease pandemic preparedness. It recognizes that the same systems, capacities, knowledge, and tools can be leveraged and applied for groups of pathogens based on their mode of transmission (respiratory, vector-borne, foodborne etc.). The PRET initiative incorporates the latest tools and approaches for shared learning and collective action established during the COVID-19 pandemic and other recent public health emergencies.
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Severe and difficult asthma in a low- and middle-income country (LMIC) can relate to lack of availability of basic medications; potentially reversible factors such as poor adherence or comorbidities such as obesity inhibiting a good response to trea
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tment; and (rarely) true severe, therapy-resistant asthma. However, definitions of severity should encompass not merely doses of prescribed medication, but also underlying risk. The nature of asthmatic airway disease shows geographical variation, and LMIC asthma should not be assumed to be phenotypically the same as that in high-income countries (HICs). The first assessment step is to ensure another diagnosis is not being missed. Largely, political action is needed if children with asthma are to get access to basic medications. If a child is apparently not responding to low dose, simple medications, the next step is not to increase the dose but perform a detailed assessment of what factors (for example co-morbidities such as obesity, or social factors like poor adherence) are inhibiting a treatment response; in most cases, an underlying reason can be found. An assessment of risk of future severe asthma attacks, side-effects of medication and impaired lung development is also important. True severe, therapy-resistant asthma is rare and there are multiple underlying molecular pathologies. In HICs, steroid-resistant eosinophilia would be treated with omalizumab or mepolizumab, but the cost of these is prohibitive in LMICs, the biomarkers of successful therapy are likely only relevant to HICs. In LMICs, a raised blood eosinophil count may be due to parasites, so treating asthma based on the blood eosinophil count may not be appropriate in these settings.
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Asthma has a significant impact on people of all ages, particularly children. A lack of universally accepted case definition and confirmatory tests and a poor understanding of major risks interfere with a global response. We aimed to provide global
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estimates of asthma prevalence and cases in 2019 across four main epidemiological case definitions – current wheezing, ever wheezing, current asthma, and ever asthma. We further investigated major associated factors to determine regional and national distributions of prevalence and cases for current wheezing and ever asthma.
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Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Uni
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on Framework for Antimicrobial Resistance Control 2020 – 2025, which is tailored to meet the specific needs of African nations through a coordinated approach. While most countries in the region have developed and prioritized National Action Plans (NAPs) to tackle AMR, the overall response remains inadequate given the magnitude of the threat, which endangers human, animal, environmental, aquatic, and plant health.
Africa bears a significant burden of infectious diseases, accounting for approximately 95% of malaria deaths, 70% of people living with HIV, and 25% of TB deaths globally. In 2019, AMR was linked to approximately 55,000 deaths from HIV, 30,000 from malaria, and 255,000 overall. Major drivers of AMR in the region include the overuse and misuse of antimicrobials in human and food systems, migration, suboptimal vaccination rates, and environmental contamination from hospital and pharmaceutical effluents. Additionally, there is a lack of access to quality-assured antimicrobials and diagnostics, compounded by inadequate knowledge about AMR. Unlike high-income countries, where indiscriminate antimicrobial use is the primary factor driving AMR, African countries face additional challenges, including a lack of access to clean and safe water, poor Water, Sanitation, and Hygiene (WASH) programs, inadequate infection prevention measures, and suboptimal vaccinations for preventable diseases. One in three hospitals in the region lacks clean, safe running water, and one in eight people defecate openly due to inadequate sanitation. Investments in WASH, infection prevention, and biosecurity could save approximately 700,000 lives annually.
Addressing AMR in Africa requires a comprehensive, multi-sectoral approach involving the entire society. Sustainable access to antimicrobials, including antibiotics, vaccines, and therapeutics, is crucial, as lack of access leads to more morbidity and mortality than AMR itself. Support for the region should focus on preventing infections, strengthening health and food systems, developing human resources, ensuring sustainable access to diagnostics and therapeutics, and investing in laboratory infrastructure to support surveillance and data generation.
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The active participation and engagement of health and care workers (HCWs) in health emergency preparedness, readiness and response is crucial to support risk communication, community engagement and infodemic management (RCCE-IM) interven
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tions during emergencies. HCWs hold unique positions in society – repeatedly being identified among the main influencers of people’s behaviours: they are one of the most trusted sources of health information and advice in communities and role models for the acceptance and uptake of protective measures during health emergencies. On the frontline, HCWs have valuable insights and knowledge that can be harnessed to support health emergencies across the entire emergency cycle. Between October and December 2023, the WHO Regional Office for Europe interviewed key informants on strategies and experiences to meaningfully engage HCWs during emergencies
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Médecins Sans Frontières (MSF) has set up a 20-bed cholera treatment unit (CTU) at the Renk Civil Hospital in South Sudan, in response to a cholera outbreak declared by the Ministry of Health (MoH) on 28 October. We call on all organisations in Up
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per Nile state to help prevent the spread of the disease within Upper Nile State and beyond.
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Developing Pharmacy Practice - A focus on patient care
Wiedenmayer, K. et al.
World Health Organization (WHO), International Pharmaceutical Federation (FIP)
(2006)
C_WHO
English version - This handbook sets out a the new paradigm for pharmacy practice. Its aim is to guide pharmacy educators in pharmacy practice, to educate pharmacy students and to guide pharmacists in practice to update their skills. The handbook, which brings together practical tools and knowledge,
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has been written in response to a need to define, develop and generate global understanding of pharmaceutical care at all levels.
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In the last quarter of 2009, tropical storms Ketsana, Pharma and Santi poured the heaviest rainfall on Metro Manila in more than 40 years. This caused massive flooding in the National Capital Region and Region IVA. A few weeks later, the world's biggest leptospirosis outbreak reported more than 200
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deaths and 3 000 cases in various hospitals around the country.
The Global Outbreak Alert Response (GOARN) investigated the outbreak, and recommended that an integrated information system in emergencies be established, for it would provide early warning for potential disease outbreaks.
Surveillance in Post Extreme Emergencies and Disasters or SPEED was conceptualized to provide real time health information reporting after a disaster.
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The Story of Cholera is seen as a great tool to promote basic hygiene practices and has been narrated in Arabic to be shown in these Settlements. It is seen as both a prevention measure against potential cholera outbreak and/or other type of diarrheal diseases. Tested on site it has received a great
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welcome from the refugee community and is expected to have a major impact in the hygiene promotion response.
Download flashcards, video and mobile phone version at: http://globalhealthmedia.org/story-of-cholera/videos/registration/
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The South Sudan Nutrition Cluster is a coordination mechanism which aims to ensure coherent, strategic and effective emergency nutrition responses, working with national and international partners on agreed priorities. The Cluster focuses on coordination, capacity building, emergency preparedness, a
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ssessment and response, and improving coverage of emergency nutrition programs. On this website Nutrition Cluster partners can find relevant information to support their emergency nutrition activities, and interested stakeholders can find relevant information concerning the nutritional response to undernutrition in South Sudan:
https://sites.google.com/site/nutritionclustersouthsudan/
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Clinical guideline, Methods, Evidence and Recommendations
In this guideline the following is covered: information needs of people with chronic hep
titis B and their carers; where children, young people and adults with chronic hepatitis B a-
should be assessed; assessment of liver disease, includi
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ng the use of non-invasive tests and genotype testing; criteria for offering antiviral treatment; the efficacy, safety and cost effectiveness of currently available treatments; selection of first-line therapy; management of treatment failure or drug resistance; prophylactic treatment during im-
munosuppressive therapy; and monitoring for treatment response
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The scale of West Africa’s Ebola epidemic has been attributed to the weak health systems of affected countries,
their lack of resources, the mobility of communities and their inexperience in dealing with Ebola. This briefing for African Affairs argues that these explanations lack important contex
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t. The briefing examines responses to the outbreak and offers a different set of explanations, rooted in the history of the region and the political economy of global health and development. To move past technical discussions of “weak” health systems, it highlights how structural violence has contributed to the epidemic. As part of this, local people – their beliefs, concerns and priorities – have been marginalised. Both the crisis response and post-Ebola ‘reconstruction’ will be strengthened by acknowledgment of its long term structural underpinnings and from a more collaborative inclusion of local people.
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Ebola virus disease preparedness strengthening team Guinea-Bissau country visit 12–20 November 2014
World Health Organization
(2014)
The main objective of this mission was to assess the level of preparedness of Guinea-Bissau in respect of the WHO consolidated checklist. The checklist helps countries to assess and test their level of readiness it is being used to identify concrete action to be taken and where countries will requir
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e support from partners. It lists 10 key components and tasks for both countries and the international community that should be completed within 30, 60 and 90 days from the date of issue of the list, with minimal requirements for equipment, material and human resources.
The components include: overall coordination; rapid response teams; public awareness and community engagement; infection prevention and control; epidemiological and laboratory surveillance; contact tracing; points of entry; laboratory; social mobilization and risk communication; budget.
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A Wake-Up Call: Lessons from Ebola for the world’s health systems
recommended
Save the Children
(2015)
Almost 30 countries vulnerable to a new Ebola-style Epidemic, jeopardising the future of millions of Children. The report ranks the world’s poorest countries on the state of their public health systems, finding that 28 have weaker defences in place than Liberia where, alongside Sierra Leone and Gu
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inea, the current Ebola crisis has already claimed 9,000 lives, and provoked an extraordinary international response to help contain it.
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The Government of Liberia (GoL) reports three additional EVD cases linked to the Margibi County cluster, including one in Liberia’s Montserrado County; new confirmed case total reaches six
Recently extended Operation Northern Push strengthens contact tracing and EVD prevention activities
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in Sierra Leone
The Government of Guinea (GoG) and EVD response actors investigate source of infection for EVD-positive nurse in Forécariah Prefecture, the area’s first confirmed case among health care workers since March
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This Ebola Communication Preparedness Implementation Kit (I-Kit) provides national and local stakeholders, as well as program managers, with key considerations and a roadmap for instituting and implementing critical, relevant, practical and timely communication for responding to the threat of an Ebo
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la Virus Disease (EVD) outbreak. The I-Kit guides countries in social and behavior change communication (SBCC) and risk communication activity planning, including communication plan development for every stage of an Ebola response
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GO pre-deployment training: participant handbook
recommended
This is a pre-deployment training, tailored specially to the Ebola outbreak in West Africa, offered to WHO personnel, consultants, and key partners. The material covered in modules 1-4 is applicable and useful to frontline response workers, national
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and international. Only Module 5, which focuses on operational aspects - the code of conduct for international civil servants and human resources arrangements for WHO deployees, are specifically geared to all internationally recruited personnel and to WHO deployees respectively
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All personnel deployed by the World Health Organization (WHO) to any type of public health or humanitarian emergency need to have basic knowledge and skills to perform effectively and safely. That is why it is essential to be trained prior to deployment. GO training is a comprehensive package of mod
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ular pre-deployment training materials for WHO staff, consultants and partners deployed for the Ebola outbreak response in West Africa. Each module is accompanied with a video lecture for self-learning purposes
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This toolkit is intended to support GBV staff to build disability inclusion into their work, and to strengthen the capacity of GBV practitioners to use a survivor-centered approach when providing services to survivors with disabilities.
The tools are designed to complement existing guidelines, prot
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ocols and tools for GBV prevention and response, and should not be used in isolation from these. GBV practitioners are encouraged to adapt the tools to their individual programs and contexts, and to integrate pieces into standard GBV tools and resources.
You can download from English, French and Arabic Version
http://www.womensrefugeecommission.org/research-resources/building-capacity-for-disability-inclusion-in-gender-based-violence-gbv-programming-in-humanitarian-settings-overview/
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More than 800,000 asylum seekers and migrants have arrived in Europe by sea in 2015, with most traveling onward to northern and western EU countries. According to UNHCR, the United Nations refugee agency, 84 percent were from Syria, Afghanistan, Eritrea, Somalia, or Iraq – all countries experienci
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ng conflict, widespread violence and insecurity, or countries with highly repressive governments. European Union governments should take urgent action to bring Europe’s response to the refugee challenge, now a full blown EU crisis, in line with their legal responsibilities and stated values.
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