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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children
recommended

Turkova, A.; G.H. Wills, E. Wobudeya, et al. (2022) C2

N Engl J Med 2022; 386:911-922, DOI: 10.1056/NEJMoa2104535 Four months of antituberculosis treatment was noninferior to 6 months of treatment in children with drug-susceptible, nonsevere, smear-negative tuberculosis (SHINE Study)

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The environmental footprint of health care: a global assessment

Lenzen, M.; A. Malik, M.Li, et al. (2020) CC

Lancet Planet Health 2020; 4: e271–79

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WHO global air quality guidelines: particulate matter (‎PM2.5 and PM10)‎, ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide

World Health Organization WHO (2021) C_WHO

The global burden of disease associated with air pollution exposure exacts a massive toll on human health worldwide: exposure to air pollution is estimated to cause millions of deaths and lost years of healthy life annually. The burden of disease attributable to air pollution is now estimated to be ... more

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Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes: An updated analysis with a focus on low- and middle-income countries

Prüss-Ustün A., Wolf J., Bartram J., et al. (2019) CC

Int J Hyg Environ Health. 2019 Jun; 222(5): 765–777. doi: 10.1016/j.ijheh.2019.05.004; To develop updated estimates in response to new exposure and exposure-response data of the burden of diarrhoea, respiratory infections, malnutrition, schistosomiasis, malaria, soil-transmitted helminth infec... more

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Water, Sanitation and Hygiene: The foundation for building resilience in climate‑vulnerable communities

Omasete J., Forster J., Geere J., et al. Water Aid (2022) CC

This report, which involved input from across WaterAid, in particular from the Programme Support Unit (PSU) of WaterAid UK, includes case studies from a variety of countries, including Bangladesh, Burkina Faso, Eswatini, Ethiopia, Ghana, India and Nepal, each demonstrating what must be done now to i... more

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The Impact of Climate Change on Mental Health: A Systematic Descriptive Review

Cianconi, P.; Betrò, S.; Janiri, L. (2020) CC

BackgroundClimate change is one of the great challenges of our time. The consequences of climate change on exposed biological subjects, as well as on vulnerable societies, are a concern for the entire scientific community. Rising temperatures, heat waves, floods, tornadoes, hurricanes, droughts, fir... more

Tool to assess impact of human resources for health investments on HIV, TB and malaria services and health outcomes

World Health Organization WHO (2022) C_WHO

The WHO Global strategy on human resources for health: workforce 2030 encourages development partners and global health initiatives to leverage their support to health systems in countries to sustainably strengthen the health workforce. To assess the impact of these investments, a methodology was de... more

Progress on household drinking water, sanitation and hygiene 2000-2020: Five years into the SDGs

World Health Organization WHO; UNICEF (2021) C_WHO

The Joint Monitoring Programme (JMP) report – Progress on household drinking water, sanitation and hygiene 2000 - 2020 – presents estimates on household access to safely managed drinking water, sanitation and hygiene services over the past five years, and assesses progress toward achieving the s... more

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The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2019–2020

European Centre for Disease Prevention and Control ECDC (2022) CC

This report provides an overview of the main findings of the 2019–2020 harmonised AMR monitoring in the main food-producing animal populations monitored, in carcase/meat samples and in humans. Where available, monitoring data obtained from pigs, calves, broilers, laying hens and turkeys, as well a... more

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A global inventory of small floating plastic debris

van Sebille, E.; C. Wilcox, L. Lebreton et al. IOP Science (2015) CC

Environmental Research Letters Microplastic debris floating at the ocean surface can harm marine life. Understanding the severity of this harm requires knowledge of plastic abundance and distributions. Dozens of expeditions measuring microplastics have been carried out since the 1970s, but they ha... more

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Plastic Pollution in the World's Oceans: More than 5 Trillion Plastic Pieces Weighing over 250,000 Tons Afloat at Sea

Eriksen, M.; L. C. M. Lebreton, H. S. Carson et al. PLOS One (2014) CC

PlosOne December 10, 2014 https://doi.org/10.1371/journal.pone.0111913 Plastic pollution is ubiquitous throughout the marine environment, yet estimates of the global abundance and weight of floating plastics have lacked data, particularly from the Southern Hemisphere and remote regions. Here we re... more

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Pharmaceutical pollution of the world’s rivers

Wilkinson, J.L.; A.B. A. Boxall, D. W. Kolpin, et al. (2022) CC

PNAS 119 (8) e2113947119 | https://doi.org/10.1073/pnas.2113947119 Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, m... more

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Spatiotemporal distribution of antimicrobial resistant organisms in different water environments in urban and rural settings of Bangladesh

Asaduzzaman, M. et al. (2022) CC

The authors conduct an integrated survey of Antimicrobial Resistant Organisms (AMR) in drinking water, wastewater and surface water in three settings in Bangladesh: rural households, rural poultry farms, and urban food markets. Results show that untreated water discharged from rural households, poul... more

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Public health and climate change adaptation policies in the European Union

World Health Organization WHO (2017) C_WHO

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Integration gelungen? Lebenswelten und gesellschaftliche Teilhabe von (Spät) Aussiedlerinnen und (Spät) Aussiedlern

N. Friedrichs; Graf, J. Sachverständigenrat für Migration und Integration (2022) CC

Die Studie untersucht auf Basis von Daten des Mikrozensus sowie des SVR Integrationsbarometers den Stand der Integration von (Spät) Aussiedlerinnen und (Spät)Aussiedlern in Deutschland in zahlreichen Lebensbereichen

Understanding the relationship between child marriage and female genital mutilation

UN Children's Fund UNICEF (2022) C_UNICEF

Child marriage and female genital mutilation (FGM) threaten the well-being of millions of girls around the world. Both have existed for generations, as manifestations of gender inequality, and have been propagated by discriminatory norms that devalue girls. In many countries where both child marriag... more

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Understanding the association between parental attitudes and the practice of female genital mutilation among daughters

Cappa, C.; C. Thomson; C. Murray Plos One (2019) CC

Female genital mutilation is a harmful traditional practice that violates girls’ right to health and overall well-being. Most research cites social acceptance, marriageability, community belonging, proof of virginity, curbing promiscuity, hygiene, and religion as motivations for the practice. I... more

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Testing for Ethnic Discrimination in Outpatient Health Care: Evidence from a Field Experiment in Germany

M. Halla; Kah, C.; Sausgruber, R. Johannes Kepler University Linz (2022) CC

To test for ethnic discrimination in access to outpatient health care services, we carry out an email-correspondence study in Germany. We approach 3,224 physician offices in the 79 largest cities in Germany with fictitious appointment requests and randomized patients’ characteristics. We find t... more

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Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change

Masson-Delmotte, V.; P. Zhai; A. Pirani; et al. Cambridge University Press (2021) CC

This Summary for Policymakers (SPM) presents key findings of the Working Group I (WGI) contribution to the IPCC’s Sixth Assessment Report (AR6) on the physical science basis of climate change. The report builds upon the 2013 Working Group I contribution to the IPCC’s Fifth Assessment Report (AR5... more

Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children recommended

Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children
recommended