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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Mpox Multi-country external situation report n. 37

World Health Organisation (WHO) (2024) C_WHO

22 September 2024

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Tuberculosis care and control in refugee and displaced populations: an inter-agency field manual

M.A. Connolly, M. Gayer and S. Ottmani World Health Organization (2007) C_WHO

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Rwanda Demographic and Health Survey 2010

National Institute of Statistics of Rwanda (NISR) [Rwanda], Ministry of Health (MOH) [Rwanda], and ICF International (2012) C2

The government of Rwanda conducted the 2010 Rwanda Demographic and Health Survey (RDHS) to gather up-to-date information for monitoring progress on healthcare programs and policies in Rwanda, including the Economic Development and Poverty Reduction Strategy (EDPRS), the Millennium Development Goals ... more

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Plague manual: epidemiology, distribution, surveillance and control Chapter 3-5

World Health Organization (1999) C_WHO

External Link

Leaving no one behind: Humanitarian effectiveness in the age of the sustainable development goals

UN Office for the Coordination of Humanitarian Affairs (2016) C2

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Protection interventions for older people in emergencies

Allaire, A. Help Age International (2015) CC

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To Stay and Deliver - Good practice for humanitarians in complex security environments

Jan Egeland, Norwegian Institute of International Affairs; Adele Harmer and Abby Stoddard, Humanitarian Outcomes Office for the Coordination of Humanitarian Affairs (OCHA) (2011) C2

The report offers an analysis of the broader challenges to securing humanitarian action and recommends areas for improvement. This study will contribute to improving the way humanitarians ‘do business’ in complex security environments. Document also available in French, Arabic and Spanish.

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Evaluating Humanitarian Action Guide
recommended

John Cosgrave and Margie Buchanan-Smith ALNAP (2016) C1

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Levels and Determinants of Out-of-Pocket Health Expenditures in the Democratic Republic of the Congo, Liberia, Namibia, and Rwanda. DHS Analytical Studies No. 59

Wang, Wenjuan, Gheda Temsah, and Emily Carter (2016) C1

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Progress against the polio eradication and endgame strategic plan 2013-2018: Semi-annual status report, January to June 2017

Global Polio Eradication Initiative (2017) C1

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Rwanda Demographic and Health Survey 2014-15

National Institute of Statistics of Rwanda (NISR) [Rwanda], Ministry of Health (MOH) [Rwanda], and ICF International. (2015) C2

The main objective of the 2014-15 RDHS was to obtain current information on demographic and health indicators, including family planning; maternal mortality; infant and child mortality; nutrition status of mothers and children; prenatal care, delivery, and postnatal care; childhood diseases; and ped... more

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Poverty Mapping Report, 2013/14

National Institute of Statistics of Rwanda (NISR) (2017) C2

This report complements the previous poverty analysis studies by presenting a series of poverty maps of Rwanda at cell and sector levels, based on data from EICV4 and the 2012 Population and Housing Census. A poverty map is simply a map that shows the incidence of poverty in different areas of the c... more

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Rwanda: 2013-2014 ANNUAL REPORT - Tuberculosis, other respiratory communicable diseases and Leprosy control in Rwanda

Rwanda Biomedical Center - Institute of HIVAIDS, Disease prevention & Control (IHDPC), TB & Other Respiratory Communicable Diseases Division (2014) C2

This report has been developed, based on data provided by the TB & ORD surveillance system from across Rwanda. It provides a comprehensive picture of the occurrence and management of TB & ORD and Leprosy in Rwanda. It is structured based on the 2013-2018 Rwanda TB national strategic plan (2013-2018 ... more

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Rwanda Annual Report on HIV and AIDS, 2010-2011

Ministry of Health, Rwanda & Rwanda Biomedical Centre (2011) C2

The 2010-2011 National Annual Report on HIV program presents the progress in implementing the strategies and activities articulated in the National Strategic Plan on HIV and AIDS 2009-2012 commonly referred to as the HIV NSP. The report presents consolidated information regarding the outputs in the ... more

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RWANDA VISION 2020 Revised 2012

Republic of Rwanda (2012) C2

The Vision 2020 is a reflection of our aspiration and determination as Rwandans, to construct a united, democratic and inclusive Rwandan identity, after so many years of authoritarian and exclusivist dispensation. We aim, through this Vision, to transform our country into middle - income nation in w... more

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Addressing Forced Displacement through Development Planning and Co-operation: Guidance for Donor Policy Makers and Practitioners

Mwangi, Annabel; Gamez, Laura et al. Organisation for Economic Co-operation and Development (OECD) (2017) C1

OECD Development Policy Tools
Recognising that donor policies and responses constantly evolve, this guidance recommends that donors operating in situations of forced displacement prioritise three broad areas of work, where they can best contribute to existing capacities at the national, regiona... more

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A World at Risk

Global Preparedness Monitoring Board (2019) C_WHO

Annual report on global preparednessfor health emergencies The next pandemic is not a question of if, but when—and the world is woefully unprepared, according to the first annual report from the Global Preparedness Monitoring Board. The WHO and the World Bank convened the independent group after ... more

Democratic Republic of Congo Urbanization Review

World Bank (2020) C1

Productive and Inclusive Cities for an Emerging Democratic Republic of Congo

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Tips for Engaging Communities during COVID-19 in Low-Resource Settings, Remotely and In-Person
recommended

GOARN Risk Communication and Community Engagement (RCCE) Coordination Working Group, et al. (2020) C_WHO

This brief provides key considerations for engaging communities on COVID-19 and tips for how to engage where there are movement restrictions and physical distancing measures in place, particularly in low-resource settings.

Evaluating Humanitarian Action Guide recommended

Tips for Engaging Communities during COVID-19 in Low-Resource Settings, Remotely and In-Person recommended

Evaluating Humanitarian Action Guide
recommended

Tips for Engaging Communities during COVID-19 in Low-Resource Settings, Remotely and In-Person
recommended