Long Acting Muscarinic Antagonists (LAMA) such as tiotropium and glycopyrronium are used in the management of COPD1. They have been shown to improve lung function, quality of life and exercise tolerance. They have also been associated with reduced COPD-related exacerbations, associated hospitalisati...ons and duration of hospital stay. Both the South African Thoracic Society (SATS) and Global Initiative for Chronic Obstructive Lung Disease (GOLD), guidelines recommend the use of long acting anticholinergic drugs (or long acting beta agonists) in moderate to very severe disease as defined by lung function (FEV1). The most up to date guideline, utilizing the GRADE methodology (European Respiratory Society guidelines of 2017), confirms their superiority over long acting β agonists (LABA) as monotherapy for COPD in that LAMA's have demonstrated greater efficacy in terms of exacerbation reduction, with similar safety profile.2 These recommnedations are supported by published peer-reviewed
evidence including individual papers and Cochrane reviews.
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Le choléra reste une menace mondiale pour la santé publique et un indicateur clé du
manque de développement social. La transmission du choléra est étroitement liée à
l’accès insuffisant à l’eau potable et à l’assainissement. Les zones typiques à risque sont
notamment les bido...nvilles périurbains et les zones rurales où les infrastructures de base
ne sont pas disponibles, ainsi que les camps de personnes déplacées ou de réfugiés où
les conditions de vie et l’accès à l’eau et aux systèmes d’assainissement sont insuffisants.
En 2015, plus de 170 000 cas et 1 300 décès (TL : 0,8 %) ont été signalés à l’OMS dans
42 pays, dont 41 % en Afrique 37 % en Asie et 21 % en Haïti. C
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The Core Set of Indicators and respective Indicator Data Sheets aim to pave the way towards a common understanding, greater consistency and comparability across countries and alignment of results chains of German Development Cooperation in the field of health and social health protection with the in...ternationally recognized health systems framework of WHO and International Health Partnership (IHP+).
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This research is one case in a study commissioned by the World Food Programme to investigate the participation of recipient community in the targeting and management of humanitarian food assistance in complex emergencies. The study involved a substantial desk review of existing documentation, and th...ree weeks of field work in February and March 2008. The purpose of the study was to understand the ways in which participatory or community-based approaches to targeting have been attempted, within the definition of community-based targeting suggested by WFP. The study was not an evaluation of targeting methods, although some critical examination of targeting was necessary in order to understand the constraints on community participation.
Related resources
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Handout presentations in PDF for illustrating lectures
Accessed May 2014
Lunsar, Port Loko District, Sierra Leone
Interim emergency guidelines