The sub-Saharan African region, carries 90% of the over 250 million cases of schistosomiasis occurring worldwide. In this region, after Nigeria, Tanzania is second country having the highest cases of schistosomiasis and approximately 51.5%0 of the Tanzanian population is either exposed or live in ar...eas with high risk of exposure. The country is endemic to both Schistosoma mansoni and Schistosoma haematobium, these infections are common in communities characterised with limited access to water, sanitation, hygienic practices and health services. Schistosoma mansoni infection is associated with hepatosplenic disease characterised with hepatomegaly, splenomegaly, progressive periportal fibrosis (PPF) which can lead to portal hypertension and its related sequelae, mainly ascites, liver surface irregularities, oesophageal varices and haematemesis. The main consequences of S. haematobium infection are haematuria, dysuria, nutritional deficiencies, urinary bladder lesions, hydronephrosis, urinary bladder squamous cell carcinoma and in children, growth retardation. Preventive chemotherapy using mass drug administration (MDA) of praziquantel targeting primary school aged children is the main strategy for controlling schistosomiasis in Tanzania.
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Leptospirosis is a perplexing conundrum for many. In the existing literature, the pathophysiological mechanisms pertaining to leptospirosis is still not understood in full. Considered as a neglected tropical zoonotic disease, leptospirosis is culminating as a serious problem worldwide, seemingly exi...sting as co-infections with various other unrelated diseases, including dengue and malaria. Misdiagnosis is also common as non-specific symptoms are documented extensively in the literature. This can easily lead to death, as the severe form of leptospirosis (Weil’s disease) manifests as a complex of systemic complications, especially renal failure. The virulence of Leptospira sp. is usually attributed to the outer membrane proteins, including LipL32. With an armament of virulence factors at their disposal, their ability to easily adhere, invade and replicate within cells calls for a swift refinement in research progress to establish their exact pathophysiological framework. As an effort to reconstitute the current knowledge on leptospirosis, the basis of leptospiral infection, including its risk factors, classification, morphology, transmission, pathogenesis, co-infections and clinical manifestations are highlighted in this review. The various diagnostic techniques are also outlined with emphasis on their respective pros and cons.
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These training materials apply to all healthcare facilities that are not designated MVD treatment facilities.
Effective infection prevention and control (IPC) is the cornerstone of every health system. As of 2023, 17 Member States have a functioning IPC programme; 19 countries have developed national IPC guidelines; and 13 countries have adopted multimodel intervention strategies to improve th
Recommendations for a public health approach
2010 revision
Here you can download Posters in English, French and Portuguese
This film presents an overview of basic steps to prevent infection at birth.
Keep Safe – Keep Serving; Liberia: Updated Sept 25 2014.
This document is intended to inform infection prevention and control practices and supply needs in healthcare facilities. As the Ebola outbreak evolves, the document will need to be adapted accordingly.
The guidance provides considerations... for establishing Ebola Care Centres. Because needs and resources may vary in different settings, these recommendations should be adapted to the situation in each county
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The BMJ has made all of its articles referring to the Ebola outbreak free to access.
The content includes latest guidance for healthcare workers, which 'will continue to update healthcare workers, outside of west Africa, with the latest guidance from the UK's Health Protection Agency and the US Cen...ter for Disease Control'
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This core package of materials provides a comprehensive introduction to the FAST strategy: a focused approach to stopping TB spread in congregate settings. This core package is composed of a booklet, job aids, posters, and a button which serves as a visual reminder to staff and patients of the impor...tance of this strategy in TB control. FAST can be implemented in both general and TB specific medical settings. Download the complete package from the website https://drtbnetwork.org/fast-tb-infection-control-strategy-core-package
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Fifth interim report to the SMAC program, DFID Freetown
Key strategies for preventing further infection are isolation of the patient in an Ebola care facility, “safe burial”, and quarantine of those exposed to Ebola cases. Equally important is social recognition that isolation, safe burial and ...quarantine are necessary to break the transmission chain. Thus it is important to ask how, and how quickly, communities learn about the risks of infection and the necessity of steps to reduce and eliminate these risks
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This series highlights current challenges to the management of Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, non-gonococcal urethris, bacterial vaginosis, syphilis and Trichomonas vaginalis. We have assembled a collection of state-of-the-art reviews that capture the latest evi...dence and opinions on where future treatment efforts should be placed.
BMC Infectious Diseases
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This document offers suggested risk communication actions in relation to Zika virus infection and other health issues linked to this disease. It is directed toward ministers of health and other health sector actors who, with their national (multidisciplinary) teams for communication and social mobil...ization, will be able to adapt the provided information to the needs of their countries and audiences.
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