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Directrices de Laboratorio para la Detección y el Diagnóstico de la Infección con el coronavirus del Síndrome Respiratorio del Medio Oriente (MERS–CoV)

Pan American Health Organization PAHO (2022) C_WHO
Los coronavirus son un grupo de virus ARN altamente diversos de la familia Coronaviridae que se dividen en 4 géneros: alfa, beta, gamma y delta, y que causan enfermedades de leves a graves en humanos y animales (1-3). Existen coronavirus humanos endémicos como los alfacoronavirus 229E y NL63 y l... more
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Norma de la OMS. Acceso universal a las pruebas de diagnóstico rápido de la tuberculosis

Pan American Health Organization (PAHO) (2023) C_WHO
En la reunión de alto nivel de las Naciones Unidas del 2018 se fijó el objetivo de tratar al menos a 40 millones de personas con tuberculosis (TB) entre el 2018 y el 2022; sin embargo, en el 2021 ese objetivo solo se había cumplido en un 66%. Las pruebas ... son fundamentales para lograr el objetivo, pero constituyen un eslabón débil en la continuidad de la atención. Las pruebas de diagnóstico rápido recomendadas por la Organización Mundial de la Salud (PDRO) son sumamente precisas, acortan el tiempo hasta el inicio del tratamiento, influyen en resultados importantes para el paciente y son costo-eficaces. Aunque el objetivo para el año 2025 es que todos los pacientes notificados se hagan inicialmente una PDRO, en el 2021 tan solo el 38% se hizo una PDRO como prueba inicial, y se determinó que el acceso a las pruebas diagnósticas era un problema crítico. Una de las principales consecuencias del uso insuficiente de las PDRO es la gran brecha en la detección de la farmacorresistencia. La presente Norma de la OMS: Acceso universal a las pruebas de diagnóstico rápido de la tuberculosis se basa en las directrices de la OMS y en el manual operativo conexo more
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Recommended selection criteria for procurement of malaria rapid diagnostic tests

World Health Organization WHO (2018) C_WHO
This WHO information note provides an updated list of recommended criteria for selecting RDTs for malaria, and highlights the performance of RDTs evaluated by the WHO malaria RDT product testing programme. It also provides an overview of additional considerations in the procurement of rapid tests.
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Critères de choix recommandés pour l’achat de tests de diagnostic rapide du paludisme

Organisation Mondiale de la Santé OMS (2019) C_WHO
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Multidrug-resistant tuberculosis in Ethiopia: efforts to expand diagnostic services, treatment and care

F. Biadglegne, U. Sack, A. C. Rodloff (2014) C1
Antimicrobial Resistance and Infection Control 2014,3 :31
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Recommendations for national SARS-CoV-2 testing strategies and diagnostic capacities
recommended

World Health Organization WHO (2021) C_WHO
Interium guidance, 25 June 2021Timely and accurate diagnostic testing is an essential tool in preventing and controlling the spread of COVID-19. This document describes recommendations for national testing strategies and the use of PCR and rapid ant... more
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Manual de orientación rápida para la utilización de estudios radiológicos de tórax en el diagnóstico de la COVID-19
recommended

Organización Mundial de la Salud OMS (2020) C_WHO
A partir de que el SARS-CoV-2 se detectó en China en diciembre de 2019, la COVID-19 se ha convertido rápidamente en una pandemia. Los pacientes con COVID-19 presentan síntomas respiratorios inespecíficos de intensidad variable y en ocasiones se les debe prestar ventilación asistida avanzada. ... more
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Recomendações para estratégias nacionais de testagem para SARS-CoV-2 e capacidades diagnósticas

Organización Mundial de Saude and OPAS OPAS (2021) C_WHO
Orientação provisória 25 de junho de 2021 Recommendations for national testing strategies for SARS-CoV-2 and diagnostic capabilities
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Lista de medicamentos essenciais para tratamento de pacientes admitidos nas unidades de terapia intensiva com suspeita ou diagnóstico confirmado da COVID-19 (LMEUTI-COVID-19)

Pan American Health Organization (PAHO), OPS (2022) C_WHO
Tercera versión, 1 de febrero del 2022. Estas orientaciones tienen por objetivo contribuir a que los sistemas de salud prioricen los medicamentos esenciales que deben estar disponibles y ser asequibles para manejar los pacientes en las unidades de cuidado intensivos durante las emergencias de salud... more
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Lista de medicamentos esenciales para el manejo de pacientes que ingresan a unidades de cuidados intensivos con sospecha o diagnóstico confirmado de COVID-19
recommended

Pan American Health Organisation PAHO (2020) C_WHO
24 marzo 2020 El objetivo de este documento es elaborar una lista de medicamentos esenciales para manejar los pacientes en unidades de cuidados intensivos con sospecha o diagnóstico confirmado de COVID -19. Incluye principios activos con su forma ... more
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Lista de medicamentos esenciales para el manejo de pacientes que ingresan a unidades de cuidados intensivos con sospecha o diagnóstico confirmado de COVID 19. Tercera versión, 1 de febrero del 2022
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Organización Mundial de la Salud OMS OPS (2022) C_WHO
List of essential medicines for the management of patients admitted in intensive care units with a suspected or confirmed diagnosis of COVID 19. Third version, 1 February 2022
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iagnostic Gaps and Recommendations for Human African Trypanosomiasis: Assessment of User Needs, Use Cases, and the Diagnostic Landscape

PATH (2016) C2
In support of the London Declaration goals, PATH aims to catalyze engagement of the diagnostics industry and product development efforts. As part of this work, PATH conducted a diagnostic landscape ... more
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Updated recommendations on treatment of adolescents and children with chronic HCV infection, and HCV simplified service delivery and diagnostics 
recommended

World Health Organization WHO (2022) C_WHO
These guidelines provide updated evidence-based recommendations on the priority HCV-related topics from the 2018 WHO Guidelines for the care and treatment of persons diagnosed with chronic hepatitis C infection and the 2017 WHO Guidelines on hepatitis B and C testing. These priority areas are: ... more
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Clinical utlity of peptide microarrys in the serodiagnosis of neglected tropical diseases in sub-Saharan Africa: protocol for a diagnostic test accuracy sytematic review

Vengesai A., Naicker T., Kasambala M., et al. (2021) C2
BMJ Open 2021;11:e042279. doi:10.1136/bmjopen-2020-042279. Neglected tropical diseases tend to cluster in the same poor populations, and to make progress with their control, they will have to be dealt with in an integrated manner. Peptide microarrays may be a solution to tese problems, where diagnos... more
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Management and Control of Viral Haemorrhagic Fevers and other highly contagious viral pathogens

European Network for Diagnostics of Imported Viral Diseases (2001) C1
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Predictive values of Ebola RDTs and implications for decision-makers

World Health Organization (WHO) (2015) C_WHO
Annex to Selection and use of Ebola in vitro diagnostic assays
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cobas®SARS-CoV-2

Cobas (2020) C1
Qualitative assay for use on the cobas®6800/8800 Systems. For in vitro diagnostic use
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Antigen-detection in the diagnosis of SARS-CoV-2 infection
recommended

World Health Organization WHO (2021) C_WHO
Interim guidance, 6 October 2021 Direct detection of SARS-CoV-2 viral proteins (antigens) in nasal swabs and other respiratory secretions using lateral flow immunoassays (also known as rapid diagnostic tests, RDTs) offers a faster and less expensiv... more
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Laboratory diagnosis of Buruli ulcer
recommended

Portaels, F- World Health Organization WHO (2014) C_WHO
A manual for health care providers. This manual provides expert guidance on the laboratory techniques and procedures used in the diagnosis of Buruli ulcer, a disease caused by Mycobacterium ulcerans. Aimed at laboratory technicians and scientists working on this disease, the manual details the exac... more
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Interim Guidance on the Use of Rapid Antibody Tests for COVID-19 Response
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2020) CC
The speed of developing diagnostics for SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), has been quite remarkable. Diagnostics have focused on nucleic acid amplification test... more