Technical Update
HIV Treatment
July 2017
htb supplement: 2018 Vol 19:(1)
New drugs in development
July 2018
www.i-Base.info
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions.
Gr...am-negative bacteria, such as Klebsiella pneumoniae and Escherichia coli, can cause severe and often deadly infections that pose a particular threat for people with weak or not yet fully developed immune systems, including newborns, ageing populations, people undergoing surgery and cancer treatment.
The report highlights a worrying gap in activity against the highly resistant NDM-1 (New Delhi metallo-beta-lactamase 1), with only three antibiotics in the pipeline. NDM-1 makes bacteria resistant to a broad range of antibiotics, including those from the carbapenem family, which today are the last line of defence against antibiotic-resistant bacterial infections.
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BMC Public Health (2019) 19:1608
https://doi.org/10.1186/s12889-019-7853-3
The report and an accompanying series of studies show the global uptake of the World Health Organization (WHO) Surgical Safety Checklist in its first ten years since its launch and recommend ways the Checklist can be more effectively used to improve surgical safety for millions at risk.
The report ...found that uptake has been remarkably positive: the Checklist has been adopted in almost 90% of operating rooms in countries with a high Human Development Index (HDI), a country-level measure of health, education, and standard of living. It was referenced by at least 139 (70%) of the world's countries and is included as a national standard by the health ministries of at least 20 countries. The Checklist has also had beneficial qualitative impact, introducing a culture of safety and improved communication within surgical teams, increasing patient trust, and improving job satisfaction.
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Accessed on 28.01.2020
Dans le cadre de la mise en œuvre d’approches spécifiques à la nutrition telles que les pratiques ANJE pour lutter contre la sous-nutrition, le renforcement de la santé communautaire et du rôle des relais communautaire est essentiel. Si de nombreux projets ont été ...développés en intégrant les relais communautaires comme partenaires d’exécution, un manque d’harmonisation est constaté entre les organisations, notamment lié à une absence de statut des relais.
L’étude a pour objectif d’évaluer le fonctionnement des relais communautaires à travers la revue des politiques de santé communautaire et à partir d’études de cas dans le cadre des activités de prévention de la malnutrition aigüe, au Burkina Faso, Mali et Sénégal. 12 projets portés par 9 ONG ont été retenus, et 8 ont fait l’objet d’une analyse qualitative. Au total, 13 villages ou quartiers urbains ont été visités, couvrant plus de 130 relais communautaires, une quinzaine d’agents de santé et une centaine de représentants de la communauté.
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Research Article
Hindawi
BioMed Research International
Volume 2018, Article ID 9619684, 10 pages https://doi.org/10.1155/2018/9619684
Joint United Nations Programme on HIV/AIDS (UNAIDS).
Agenda item 5, UNAIDS/PCB (43)/18.
11-13 December 2018 | Geneva, Switzerland
UNAIDS Programme Coordinating Board
Issue date: 23 November 2018
Accessed February 6, 2020