Severe and difficult asthma in a low- and middle-income country (LMIC) can relate to lack of availability of basic medications; potentially reversible factors such as poor adherence or comorbidities such as obesity inhibiting a good response to treatment; and (rarely) true severe, therapy-resistant ...asthma. However, definitions of severity should encompass not merely doses of prescribed medication, but also underlying risk. The nature of asthmatic airway disease shows geographical variation, and LMIC asthma should not be assumed to be phenotypically the same as that in high-income countries (HICs). The first assessment step is to ensure another diagnosis is not being missed. Largely, political action is needed if children with asthma are to get access to basic medications. If a child is apparently not responding to low dose, simple medications, the next step is not to increase the dose but perform a detailed assessment of what factors (for example co-morbidities such as obesity, or social factors like poor adherence) are inhibiting a treatment response; in most cases, an underlying reason can be found. An assessment of risk of future severe asthma attacks, side-effects of medication and impaired lung development is also important. True severe, therapy-resistant asthma is rare and there are multiple underlying molecular pathologies. In HICs, steroid-resistant eosinophilia would be treated with omalizumab or mepolizumab, but the cost of these is prohibitive in LMICs, the biomarkers of successful therapy are likely only relevant to HICs. In LMICs, a raised blood eosinophil count may be due to parasites, so treating asthma based on the blood eosinophil count may not be appropriate in these settings.
more
Urbanisation has been associated with temporal and geographical differences in asthma prevalence in low-income and middle-income countries (lMics). however, little is known of the mechanisms by which urbanisation and asthma are associated, perhaps explained by the methodological approaches used to a...ssess the urbanisation-asthma relationship.
more
This video is meant to train the public on how to use some of the devices for delivery of asthma medications.
Video: How asthma is treated.
Фазы плохого настроения и подавленного состояния знакомы каждому. Это такая же часть человеческой жизни, как и периоды счастья. Но не всегда легко распознать, когд... они переходят в болезнь депрессию.
more
Children in every country, every culture and at every social level face various forms of abuse,
neglect, exploitation and violence1. The abuse takes place at home, in school, in institutions,
at work, in the community, in armed conflict and natural disasters. Much violence against
children, such ...as corporal punishment and sexual abuse, remains legal and socially approved
in many countries. Growing up with violence and abuse seriously affects a child’s development,
dignity, and physical and psychological integrity. Save the Children works to prevent
abuse and neglect from happening, ensure the victims of violence are supported and that
justice is ensured.
more
Feelings just are. They are neither good nor bad. Emotions are a natural reaction to a situation, a
person, an environment. We cannot not have feelings. The word “bad” when referring to feelings is
a inaccurate description because there is no such thing as a bad feeling. Difficult feelings do ...exist,
yes, and some people feel them more deeply than others but that does not make them bad.
more
Let’s take feelings one step further. Feelings stem from experience. “Tracing feelings back” means
tracing an uncomfortable feeling back to the source: an argument, a disappointment, a change,
an event or situation. Doing this allows you keep you feelings in check, helps you learn about your...
triggers and lets you discover unhealthy behavioral patterns you may be in a cycle of repeating.
more