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Nature, biodiversity and health: an overview of interconnections Urbanization, land use, global trade and industrialization have led to profound ... more
Prepared for the Stunting Prevention and Reduction Project - The project Medical Waste Management Plan’s (MWMP) overall objective is to prevent and/or mitigate the negative effects of increased ge... more
Leishmaniasis is a vector-borne disease with a wide variety of parasite species, reservoirs, and vectors involved in transmission. It is caused by different species of the protozoa Leishmania and is... more
The objectives of NAP are aligned with the global action plan based on national needs and priorities. The emphasis is on One Health approach with all sectors especially ... health, animal health and environment contributing towards minimizing the emergence and impact of AMR in Jordan. more
The guide to implementing the One Health Joint Plan of Action (OH JPA) at national level provides practical guidance on how countries can adopt and adapt the OH JPA to strengthen ... support national One Health action. Building on the OH JPA theory of change, this guide describes three pathways and five key steps to implement the OH JPA at national level: Pathway 1 -- Governance, policy, legislation, financing and advocacy Pathway 2 -- Organizational and institutional development, implementation and sectoral integration Pathway 3 -- Data, evidence, information systems and knowledge exchange. The stepwise approach comprises: Situation analysis including stakeholder mapping and review of existing assessment results Set-up/strengthening of a multisectoral, One Health coordination mechanism Planning for implementation, including activity prioritization and leveraging of resources Implementation of national One Health action plans Review, sharing and incorporation of lessons learned. more
March 2022. This report on good practices to combat AMR focuses on activities across human, animal, and environmental ... in European countries. The report provides a description of practices, how they were implemented, achievements, and why the practice was unique. more
The annual Joint Meeting of the Food and Agriculture Organization of the United Nations (FAO) Panel of Experts on Pesticide Residues in Food and the Envir... and the World Health Organization (WHO) Core Assessment Group on Pesticide Residues (JMPR) was held in Rome, Italy, from 13 to 22 September. The FAO panel of experts had met in preparatory sessions from 8 to 12 September. The Meeting was held in pursuance of recommendations made by previous Meetings and accepted by the governing bodies of FAO and WHO that studies should be undertaken jointly by experts to evaluate possible hazards to humans arising from the occurrence of pesticide residues in foods. During the meeting the FAO Panel of Experts was responsible for reviewing pesticide use patterns (use of good agricultural practices), data on the chemistry and composition of the pesticides and methods of analysis for pesticide residues and for estimating the maximum residue levels that might occur as a result of the use of the pesticides according to good agricultural use practices. The WHO Core Assessment Group was responsible for reviewing toxicological and related data and for estimating, where possible and appropriate, acceptable daily intakes (ADIs) and acute reference doses (ARfDs) of the pesticides for humans. This report contains information on ADIs, ARfDs, maximum residue levels, and general principles for the evaluation of pesticides. The recommendations of the Joint Meeting, including further research and information, are proposed for use by Member governments of the respective agencies and other interested parties. more
This action plan for the Kingdom Saudi Arabia to combat antimicrobial resistance has been formulated in the line of the WHO five objectives. It addresses the need for effective “one health” approach involving coordination among numerous national... more
China is one of the major countries for the production and use of antibacterial agents. Antibacterial agents are widely used in healthcare and anim... more
Leishmaniasis is a vector-borne disease with a wide variety of parasite species, reservoirs, and vectors involved in transmission. It is caused by different species of the protozoa Leishmania and is... more
Antimicrobial resistance (AMR) is a multifaceted, international public health problem, which poses a direct threat to the safety of the population of South Africa. A national response is required to complement the development of a global plan, as ar... more
Leptospirosis is a zoonotic disease with epidemic potential, especially after a heavy rainfall, caused by a bacterium called Leptospira. Leptospira interrogans is pathogenic to humans and animals,... more
Long-lasting insecticidal nets (LNs) constitute a core vector control intervention against malaria. A number of new LN products are under development and will require assessment of risks to humans. ... more
Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan ... the African Union Framework for Antimicrobial Resistance Control 2020 – 2025, which is tailored to meet the specific needs of African nations through a coordinated approach. While most countries in the region have developed and prioritized National Action Plans (NAPs) to tackle AMR, the overall response remains inadequate given the magnitude of the threat, which endangers human, animal, environmental, aquatic, and plant health. Africa bears a significant burden of infectious diseases, accounting for approximately 95% of malaria deaths, 70% of people living with HIV, and 25% of TB deaths globally. In 2019, AMR was linked to approximately 55,000 deaths from HIV, 30,000 from malaria, and 255,000 overall. Major drivers of AMR in the region include the overuse and misuse of antimicrobials in human and food systems, migration, suboptimal vaccination rates, and environmental contamination from hospital and pharmaceutical effluents. Additionally, there is a lack of access to quality-assured antimicrobials and diagnostics, compounded by inadequate knowledge about AMR. Unlike high-income countries, where indiscriminate antimicrobial use is the primary factor driving AMR, African countries face additional challenges, including a lack of access to clean and safe water, poor Water, Sanitation, and Hygiene (WASH) programs, inadequate infection prevention measures, and suboptimal vaccinations for preventable diseases. One in three hospitals in the region lacks clean, safe running water, and one in eight people defecate openly due to inadequate sanitation. Investments in WASH, infection prevention, and biosecurity could save approximately 700,000 lives annually. Addressing AMR in Africa requires a comprehensive, multi-sectoral approach involving the entire society. Sustainable access to antimicrobials, including antibiotics, vaccines, and therapeutics, is crucial, as lack of access leads to more morbidity and mortality than AMR itself. Support for the region should focus on preventing infections, strengthening health and food systems, developing human resources, ensuring sustainable access to diagnostics and therapeutics, and investing in laboratory infrastructure to support surveillance and data generation. more
Antimicrobial resistance(AMR) poses a serious threat to human, animal and environmental health.... Implementing ethical practice guidelines on how to use antimicrobials effectively and responsibly within the pig industry will contribute in reducing and preventing antimicrobial resistance within the pig industry of South Africa. Members of Pig Vet Society (PVS) SA hereby commit themselvesto put these guidelines into good use in order to preserve the future and effectiveness of antimicrobials. PVS aims to be the leader in prevention of antimicrobial resistance and to encourage the pig industry to work together in achieving this. more
Grand Challenges - Planetary Health- This guide highlights a range of resources to explore solutions to the challenges of rising global temperature, and increased industrial effluences damaging the ... more
The Lancet Planetary Health Volume 5, ISSUE 7, e466-e478, July 01, 2021 Transmission of many infectious diseases depends on interactions between humans, animals, ... the environment. Incorporating these complex processes in transmission dynamic models can help inform policy and disease control interventions. We identified 20 diseases involving environmentally persistent pathogens (ie, pathogens that survive for more than 48 h in the environment and can cause subsequent human infections), of which indirect transmission can occur from animals to humans via the environment. more
This third edition of the National Gender Statistics Report provides the updated sex-disaggregated data in twelve fields: Population and Youth; Education; Health ... Nutrition; Economic Activity and time use; Poverty & Social Protection; Justice & Human rights; Environment and Natural Resources; Decisionmaking and Public life; Infrastructure, ICT and Media; Trade and Business and Industry; Agriculture, Livestock and Forestry, and lastly the Income and Access to Finance. It should be noted that this report takes into account almost all quantitative indicators of the United Nations Minimum Set of Gender Indicators (UNMSGI) as developed by the United Nations Statistical Division (UNSD) and some of the approved quantitative SDGs gender related indicators. more
PNAS 119 (8) e2113947119 | https://doi.org/10.1073/pnas.2113947119 Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems ... humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the scale of the problem from a global perspective. Furthermore, comparison of the existing data, generated for different studies/regions/continents, is challenging due to the vast differences between the analytical methodologies employed. Here, we present a global-scale study of API pollution in 258 of the world’s rivers, representing the environmental influence of 471.4 million people across 137 geographic regions. Samples were obtained from 1,052 locations in 104 countries (representing all continents and 36 countries not previously studied for API contamination) and analyzed for 61 APIs. Highest cumulative API concentrations were observed in sub-Saharan Africa, south Asia, and South America. The most contaminated sites were in low- to middle-income countries and were associated with areas with poor wastewater and waste management infrastructure and pharmaceutical manufacturing. The most frequently detected APIs were carbamazepine, metformin, and caffeine (a compound also arising from lifestyle use), which were detected at over half of the sites monitored. Concentrations of at least one API at 25.7% of the sampling sites were greater than concentrations considered safe for aquatic organisms, or which are of concern in terms of selection for antimicrobial resistance. Therefore, pharmaceutical pollution poses a global threat to environmental and human health, as well as to delivery of the United Nations Sustainable Development Goals. more
European Journal of Biomedical and Pharmaceutical Sciences, vol.3 (2016) 1, 192-206 This review shows that if all sub areas of pharmaceutical waste management can efficiently work back to back environmen... pollution and dangers to human health can reduce significantly. more