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Psoriasis, which can involve the skin, nails and joints, is a chronic, painful, disfiguring and disabling noncommunicable disease (NCD) for which there is no cure. It negatively impacts on quality <... life. Some of those who suffer from the disease develop chronic, inflammatory arthritis (psoriatic arthritis) that leads to joint deformations and disability. People with psoriasis are also reported to be at increased risk of developing other serious clinical conditions such as cardiovascular and other NCDs more
Developmental disabilities are common. Yet, children with developmental disabilities have been neglected in health systems planning and policy provisions for ... and continue to experience stigmatization, institutionalization, barriers to access health care and inequalities in health and education outcomes. Using findings from research and practice and guided by the tenets of international human rights conventions, this WHO-UNICEF Global Report on children with developmental disabilities provides principles and approaches to intentionally include the needs and aspirations of children and young people with developmental disabilities in policy, programming and public health monitoring. It makes the case for greater accountability and proposes 10 priority actions to accelerate changes towards inclusive environments and responsive multisectoral care systems for children with developmental disabilities. more
BMJ 2020; 371 doi: https://doi.org/10.1136/bmj.m3086 Using infectious diseases sensitive to climate as indicators of climate change helps stimulate and inform public ... responses more
In this entry we are looking at smoking, alcohol consumption and the use of illicit drugs. We are studying who is using these substances, how their use has changed over time, ... we are presenting the estimates of their impact on health. Collectively, smoking, alcohol and illicit drug use kills 11.8 million people each year. This is more than the number of deaths from all cancers more

Mental, Neurological, and Substance Use Disorders

Vikram Patel, Dan Chisholm, Tarun Dua et al. International Bank for Reconstruction and Development The World Bank (2016) CC
Disease Control Priorities, 3rdEdition: Volume 4. Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact ... these disorders on the social and economic well-beingof individuals, families, and societies is large, growing, and underestimated more
Ending the epidemics of HIV, tuberculosis and malaria by 2030 is within reach, but not yet fully in our grasp. With only 11 years left, we have no time to waste. We must step up the fight now.
This Commission report aims to contribute to a new era of multilateral cooperation based on strong UN institutions to reduce the dangers of COVID-19, forestall the next pandemic, ... enable the world to achieve the agreed goals of sustainable development, human rights, and peace that governments are committed to pursue as members of the UN. We address this Commission report to the UN member states, the UN agencies and multilateral institutions, and multilateral processes such as the G20 and the G7. more
Asthma is the most common non-communicable disease in children and remains one of the most common throughout the life course. The great majority of... more
El documento La carga de los trastornos mentales en la Región de las Américas, 2018 tiene como propósito mejorar la evaluación de las necesidades en materia de salud mental en la Región de las Américas al presentar un panorama actualizado y matizado de: a) la discapacidad debida a los trastorn... more

Burden of fungal asthma in Africa: A systematic review and meta-analysis

Kwizera, R.; Musaazi, J.; Meya, D.B.; et al. PLOS ONE, which is part of the Public Library of Science (PLOS) (2019) CC2
Asthma is one of the neglected diseases in Africa with a high prevalence. Allergic fungal diseases have been reported to complicate asthma progression and treatment outcomes. However, data about fun... more
Lancet Infect Dis 2022; 22: 222–4

Global status report on alcohol and health 2018

World Health Organization (2018) C_WHO

Providing sutstainable mental and neurological health care in Ghana and Kenya

Sheena Posey Norris, Erin Hammers Forstag, and Bruce M. Altevogt Forum on Neuroscience and Nervous System Disorders; Board on Health Sciences Policy; Board on Global Health; Publisher: National Academic Press (2016) C2
Lancet Oncol 2018 Published Online September 12, 2018 http://dx.doi.org/10.1016/S1470-2045(18)30447-9
Editorial Review AIDS 2019, 33:1411–1420
Background Cardiovascular diseases (CVDs) are one of the global leading causes of concern due to the rising prevalence and consequence ... mortality and disability with a heavy economic burden. The objective of the current study was to analyze the trend in CVD incidence, mortality, and mortality-to-incidence ratio (MIR) across the world over 28 years. Methods The age-standardized CVD mortality and incidence rates were retrieved from the Global Burden of Disease (GBD) Study 2017 for both genders and different world super regions with available data every year during the period 1990–2017. Additionally, the Human Development Index was sourced from the United Nations Development Programme (UNDP) database for all countries at the same time interval. The marginal modeling approach was implemented to evaluate the mean trend of CVD incidence, mortality, and MIR for 195 countries and separately for developing and developed countries and also clarify the relationship between the indices and Human Development Index (HDI) from 1990 to 2017. Results The obtained estimates identified that the global mean trend of CVD incidence had an ascending trend until 1996 followed by a descending trend after this year. Nearly all of the countries experienced a significant declining mortality trend from 1990 to 2017. Likewise, the global mean MIR rate had a significant trivial decrement trend with a gentle slope of 0.004 over the time interval. As such, the reduction in incidence and mortality rates for developed countries was significantly faster than developing counterparts in the period 1990–2017 (p < 0.05). Nevertheless, the developing nations had a more rather shallow decrease in MIR compared to developed ones. Conclusions Generally, the findings of this study revealed that there was an overall downward trend in CVD incidence and mortality rates, while the survival rate of CVD patients was rather stable. These results send a satisfactory message that global effort for controlling the CVD burden was quite successful. Nonetheless, there is an urgent need for more efforts to improve the survival rate of patients and lower the burden of this disease in some areas with an increasing trend of either incidence or mortality. more