This Review summarizes many of the persistent biological alterations associated with childhood maltreatment including changes in neuroendocrine and neurotransmitter systems and pro-inflammatory cytokines in addition to specific alterations in brain areas associated with mood regulation. Finally, I d...iscuss several candidate gene polymorphisms that interact with childhood maltreatment to modulate vulnerability to major depression and PTSD and epigenetic mechanisms thought to transduce environmental stressors into disease vulnerability.
Neuron Review, vol. 89, March 2, 2016 pp.892-909
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3ie Impact Evaluation Report 39
Diarrhea is one of the world’s leading causes of child illness and death, and rotavirus is the most common cause of severe diarrhea. Yet it can be prevented and treated. There is a vaccine. And while hundreds of thousands of children in India will gain access to rotavirus vaccines -part of a natio...nal introduction marking Asia’s largest so far -millions of children globally still lack access. This new report from the Rota Council summarizes the latest evidence on rotavirus disease and vaccines and identifies 21 recommendations for stakeholders to scale up coverage and prevent hundreds of thousands of child deaths annually.
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This document updates the 2009 ECDC guidance on chlamydia control in Europe. It was developed by a technical expert group which conducted a critical review of the scientific evidence on the epidemiology of chlamydia and the effectiveness of screening programmes.
The aim of this guidance is to suppo...rt Member States to develop, implement or improve strategies for chlamydia control. This guidance describes the current evidence base behind the proposed options, highlights key gaps in knowledge, and suggests effective options for national chlamydia control strategies. It is directed primarily at policy advisors but should also be useful for programme managers and experts in sexual health.
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Print version ISSN 1809-9823On-line version ISSN 1981-2256
Rev. bras. geriatr. gerontol. vol.19 no.2 Rio de Janeiro Mar./Apr. 2016
http://dx.doi.org/10.1590/1809-98232016019.150040
Identificando o risco de acidente vascular cerebral e melhorando desfechos em pacientes com fibrilação atrial na América Latina
DOI: 10.1590/1516-3180.2015.0222110716
Sao Paulo Med J. 2016; 134(6):534-42
Rapid review and case studies from Member States
Depression is a leading cause of non-fatal disease burden worldwide, with a lifetime prevalence of 9% among European adult men and 17% among European adult women.
The task at hand requires substantial investments in preventive mental health care, but the potential benefits can be equally rewarding.... After all, mental wellbeing is a key resource for learning, productivity, participation and inclusion. Investing in proactive care to promote, protect and sustain mental health in the population is therefore likely to offer good value for money.
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В основе настоящих руководящих принципов лежит структура организации мероприятий в соответствии с тремя задачами:
• создание и укрепление механизмов комплексно...го предоставления услуг ПИН;
• уменьшение совокупного бремени ТБ, ВИЧ, вирусного гепатита и других сопутствующих патологий у ПИН посредством комплексного предоставления всеобъемлющих услуг; и
• обеспечение стандарта медико-санитарной помощи в тюрьмах, аналогичного стандарту оказания медикосанитарной помощи вне тюрем, за счет гармонизации мер вмешательства и налаживания связи со службами на уровне сообщества.
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The publication is designed to provide Ipas staff, trainers, partners and other health-care providers with access to up-to-date, evidence-based recommendations. In general, the recommendations are the same as those in the World Health Organization’s 2012 Safe Abortion: Technical and Policy Guidanc...e for Health Systems, Second edition. In rare cases, the recommendations have been modified due to the settings where Ipas works. In addition, if there is more current evidence to inform the recommendations, they will be updated here.
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Mood disorders
Chapter E.3
2016 edition
Other disorders
Chapter H.5.1
Trastornos del desarrollo
Capítulo C.4
Mental, Neurological, and Substance Use Disorders: Disease Control Priorities, Third Edition (Volume 4).
Patel V, Chisholm D, Dua T, et al., editors.
Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2016 Mar 14.
An essential participant in antimicrobial stewardship who has been unrecognized and underutilized is the“staff nurse.”Although the role of staff nurses has not formally been recognized in guidelines for implementing and operating antimicrobial stewardship programs (ASPs) or defined in the medica...l literature, they have always performed numerous functions that are integral to successful antimicrobial stewardship. Nurses are antibiotic first responders, central communicators, coordinators of care, as well as 24-hour monitors of patient status, safety, and response to antibiotic therapy. An operational analysis of inpatient admissions evaluates these nursing stewardship activities and analyzes the potential benefits of nurses’formal education about, and inclusion into, ASPs.
Clinical Infectious Diseases - CID 2016:62 (1 January)•CLINICAL PRACTICE
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