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WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches.
HIV drug resistance has been rarely reported among PrEP users who tested HIV positive i
...
n randomized controlled trials or open-label studies. However, PrEP-selected HIV drug resistance could potentially negatively impact the effectiveness of treatment options among PrEP users who acquire HIV, since there is a potential for overlapping resistance profiles between antiretroviral drugs used for both PrEP and first-line antiretroviral therapy.
more
Estimating HIV incidence using HIV case surveillance
World Health Organization; UNAIDS
(2017)
C_WHO
WHO working group on HIV incidence assays meeting report
10–11 December 2015
Glion, Switzerland
UNAIDS/WHO working group on global HIV/AIDS and STI surveillance
WHO/HIV/2017.03
Young people as advocates - Your action for change toolkit
IPPF (International Planned Parenthood Federation)
(2011)
C2
From choice, a world of possibilities
Want to change the world? Here's how...
"i asked: 'Why doesn't somebody do something?' Then I realized I was somebody"
On the Fast-Track to end AIDS
UNAIDS
(2019)
C2
UNAIDS | 2016–2021 Strategy
Accessed: 20.11.2019
Internally displaced children are twice invisible in global and national data. First, because internally displaced people (IDPs) of all ages are often unaccounted for. Second, because age-disaggregation of any kind of data is limited, and even more so for IDPs.
Planning adequate responses to meet
...
the needs of internally displaced children, however, requires having at least a sense of how many there are and where they are. This report presents the first estimates of the number of children living in internal displacement triggered by conflict and violence at the global, regional and national levels.
more
Yu et al. BMC Public Health (2018) 18:825 https://doi.org/10.1186/s12889-018-5731-z
Research Article
Research Article
PLOS ONE | https://doi.org/10.1371/journal.pone.0189770 January 2, 2018
Global consultation on lessons from sexual and reproductive health programming to catalyse HIV prevention for adolescent girls and young women
S. Vermund; C. Venkatraman; L. McGrory; et al,
World Health Organization; hrp human reproduction programme (research for impact)
(2016)
C_WHO
World Health Organization Department of Reproductive Health and Research
Brocher Foundation, Hermance, Geneva, Switzerland, 27–29 April 2016
Clinical Guidelines: Antiretroviral drugs for HIV prevention - Chapter 3
World Health Organization
(2019)
C_WHO
Accessed: 27.11.2019
The classification of digital health interventions (DHIs) categorizes the different ways in which digital and mobile technologies are being used to support health system needs. Historically, the diverse communities working in digital health—including government stakeholders, technologists, clinic
...
ians, implementers, network operators, researchers, donors— have lacked a mutually understandable language with which to assess and articulate functionality. A shared and standardized vocabulary was recognized as necessary to identify gaps and duplication, evaluate effectiveness, and facilitate alignment across different digital health implementations. Targeted primarily at public health audiences, this Classification framework aims to promote an accessible and bridging language for health program planners to articulate functionalities of digital health implementations.
more
Topics in Antiviral Medicine Volume 25 Issue 2 May/June 2017
When could new antiretrovirals be recommended for national treatment programmes in low-income and middle-income countries: results of a WHO Think Tank
M. Vitoriaa; N. Forda; P. Clayden; et al.
Wolters Kluwer Health; World Health Organization
(2017)
C2
Review
www.co-hivandaids.com
Volume 12 Number 4 July 2017
HIV Pipeline 2018
i-base
(2018)
C2
htb supplement: 2018 Vol 19:(1)
New drugs in development
July 2018
www.i-Base.info
The pre-clinical pipeline shows more innovation and diversity, with 252 agents being developed to treat WHO priority pathogens.
However, these products are in the very early stages of development and still need to be proven effective and safe. The optimistic scenario, the report indicates, is for
...
the first two to five products to become available in about 10 years.
more
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions.
Gr
...
am-negative bacteria, such as Klebsiella pneumoniae and Escherichia coli, can cause severe and often deadly infections that pose a particular threat for people with weak or not yet fully developed immune systems, including newborns, ageing populations, people undergoing surgery and cancer treatment.
The report highlights a worrying gap in activity against the highly resistant NDM-1 (New Delhi metallo-beta-lactamase 1), with only three antibiotics in the pipeline. NDM-1 makes bacteria resistant to a broad range of antibiotics, including those from the carbapenem family, which today are the last line of defence against antibiotic-resistant bacterial infections.
more
Report
A Project of the Joep Lange Institute July, 2018
Accessed Febr. 6, 2020
