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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC

This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more

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Eradicating yaws in Africa: challenges and progress

Tchatchouang, S. The Lancet Microbe (2022) CC

Yaws, a neglected tropical disease (NTD) of the skin caused by the bacterium Treponema pallidum subspecies pertenue, is targeted in the latest WHO NTD Roadmap for eradication by 2030. In January, 2022, WHO published a manual that outlines the key activities that Ministries of Health in endemic count... more

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Cadre d’action régional pour la maîtrise et l’élimination des maladies tropicales négligées dans le Pacifique occidental

World Health Organization WHO (2018) C_WHO

Le Cadre d’action régional vise à aider les États Membres, l’OMS et tous les autres donateurs et partenaires à travailler ensemble pour remédier systématiquement et progressivement aux diverses faiblesses relevées dans les principaux domaines programmatiques et/ou de contribuer à renforc... more

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Annual Report of the WHO Country Office in Zimbabwe, 2022

World Health Organisation (WHO) (2023) C_WHO

This report highlights the work of the World Health Organization (WHO) in Zimbabwe towards contributing to the triple billion targets in the context of the Sustainable Development Goals (SDGs

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Dépistage de la Covid-19 chez les Femmes Enceintes et les Accouchées dans Six Maternités de Brazzaville

World Health Organisation (WHO) (2023) CC

La prévalence de la covid -19 chez la femme enceinte et les accouchées semble être faible. Elles étaient asymptomatiques et le pronostic maternel était satisfaisant. Néanmoins, le risque de for.pdf

Democratic Republic of Timor-Leste Ministry of Health - Comprehensive TB Guidelines for National Tuberculosis Program, V Edition

Government of Timor-Leste; World Health Organization (2023) CC

The Democratic Republic of Timor-Leste has the highest TB incidence rate in the South East Asian Region - 498 per 100,000, which is the seventh highest in the world. In Timor-Leste TB is the eighth most common cause of death. The salient observations are as follows: In 2018, 487 (12.5%) of the... more

Management of Type 2 Diabetes Mellitus

Richardson, C.R.; Borgeson, J. R.; Harrison, V.; et al. National Library of Medicine (2021) CC2

The document "Management of Type 2 Diabetes Mellitus" provides comprehensive guidelines for the diagnosis, prevention, and treatment of type 2 diabetes in adults. It emphasizes the importance of individualized glycemic targets, lifestyle interventions like diet and exercise, and the use of medicatio... more

Issue Brief: Ukraine Conflict and the impact on Mental Health

The MEDBOX Team (2024) CC

As Russia's invasion of Ukraine progresses, the civilian population and the Armed Forces face enormous challenges. It is unsurprising that people's mental health deteriorate in such conditions. This Issue Brief provides publications and informative resources highlighting the impact on Mental Health.

TB policies in Malawi

Medicins sans frontieres; Stop TB Partnership (2020) CC2

Malawi Internationally recommended key policies uptake

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Infant feeding in the context of Ebola

UNICEFWHO (2014)

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Clinical Management of HIV in Children and Adults Malawi
recommended

Ministry of Health Malawi; Dept. of HIV and AIDS (2016) C1

Malawi Integrated Guidelines and Standard Operating Procedures for Providing HIV Services. 3rd edition 2016

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Malawi Guidelines for Clinical Management of HIV in Children and Adults

Ministry of Health, Malawi (2016) C1

This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, health surveillance assistants (HSAs), and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation... more

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Childhood Tuberculosis Education Tools for Children and their Families

S. Shah, S. Seidel TB Alliance (2015) C2

For Children and their Families October 2015

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North-east Nigeria: Case study

Edwards, Jon Médecins Sans Frontières (MSF) (2017)

This case study examines the humanitarian response to the conflict-related crisis in the North-East of Nigeria, focusing primarily on the period from 2015 to the end of 2016. The aim is test the central hypotheses of the Emergency Gap project: that the current structure, conceptual underpinning and... more

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Cotonou TB declaration

World Health Organization WHO, Regional Office for Africa (2018) C_WHO

Workshop to share best practices and lessons learned in tuberculosis case finding and treatment in Western and Central Africa, 26 - 28 March 2018

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Integrating Mental Health into Primary Health Care

World Health Organization WHO (2007) C_WHO

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Protocolo de vacunación contra la COVID-19 para personas con diagnóstico de Síndrome de Down

Ministerio de Salud, Peru (2021) CC

El presente protocolo es de aplicación en las Instituciones Prestadoras de Servicios de Salud del Ministerio de Salud, a través de las Direcciones de Redes Integradas de Servicios de Salud y de los Gobiernos Regionales, a través de las Direcciones Regionales de Salud o Gerencias Regionales de Sal... more

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Male engagement in HIV testing, treatment and prevention in eastern and southern Africa — A framework for action

UNAIDS (2022) C_WHO

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Public Health in Ukraine

akkon Hochschule für Humanwissenschaften; Institute for research in international assistance (2022) C2

Despite its rich culture, great economic potential, high level of education and last but not least its sheer size – it is the largest state whose borders lie entirely within Europe and is 1.7 times the size of the Federal Republic of Germany – Ukraine seems far away in perception and awareness. ... more

Clinical Management of HIV in Children and Adults Malawi recommended

Clinical Management of HIV in Children and Adults Malawi
recommended