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PQDx 0197-045-00 WHO
PQDx PR
March /2016, version 2.0
A comparative analysis of national HIV policies in six African countries with generalized epidemics
K. Church; F. Kiweewa, A.Dasgupta; et al.
Bull World Health Organ; PMC (US National Library of Medicine National Institutes of Health)
(2015)
C2
Bull World Health Organ 2015;93:457–467 | doi: http://dx.doi.org/10.2471/BLT.14.147215
56th directing council - 70th session of the regional committee of WHO for the Americas
Pan American Health Organization; World Health Organization (Americas); Observatorio Regional de Recursos Humanos de Salud
(2018)
C_WHO
Washington, D.C., USA, 23-27 September 2018
Provisional Agenda Item 4.6
CD56/10, Rev. 1 31 August 2018
Original: Spanish
Antiretroviral Treatment in the Spotlight: A Public Health Analysis in Latin America and the Caribbean 2013
M. A. Jiménez; S. Cabrera; J. J. Fiol; et al.
Pan American Health Organization; World Health Organization (Americas)
(2013)
C_WHO
Washington, DC, 2013
Undiagnosed tuberculosis in patients with HIV infection who present with severe anaemia at a district hospital
M. Mntonintshi; D. O’Mahony; S.Mabunda; et al.
African Journal of Primary Health Care & Family Medicine, AOSIS; NCBI (National Center for Biotechnology Information)
(2017)
CC
Original Research
African Journal of Primary Health Care & Family Medicine
ISSN: (Online) 2071-2936, (Print) 2071-2928
Open Access
Guideline: Adherence to antiretroviral therapy in adolescents and young adults (expanded version)
L. Fairlie; L. Jankelowitz; H. Ronald; et al.
Southern African HIV Clinicians Society; Right to Care (Training Health Seriously)
(2017)
C2
Recommendations, resources and references
A publication of the Southern African HIV Clinicians Society
Topics in Antiviral Medicine 25 Issue 2 May/June 2017
HIV i-Base
July 2018
Guidelines on Use of Antiretroviral Drugs for Treating and Preventing HIV in Kenya
Ministry of Health; National AIDS & STI Control Program
(2018)
C2
2018 Edition
Over 2 million children worldwide are living with HIV infection and 95% reside in sub-Saharan Africa with the majority infected through mother-to-child transmission. Infected children have a high mortality with 50% dying by 2 years of age. Their clinical presentation includes common childhood infect...ions, opportunistic infections and conditions associated with HIV/AIDS immune suppression.
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A Systematic Review and Meta-analysis
Clinical Infectious Diseases® 2016;62(12):1586–94
A healthcare worker manual. 2nd edition
The development of this National Manual for the Management of HIV-related Opportunistic Infections and Conditions for use by health care workers at the frontline of our fight against HIV/AIDS is intended to improve their understanding of the causes, preventio...n and appropriate management of opportunistic infections and conditions in adults and adolescents (OIs in children is covered effectively in the Integrated Management of Childhood Illnesses – IMCI – materials). It is also intended to be a practical guide at the clinic level, so as to improve quality of life, treatment outcomes and survival of PLHA. Crucially, this manual uses a “symptom-based” approach to support health care workers at the most basic primary level to be able to effectively initiate the care of PLHA with OIs and refer patients as appropriate (effective triage of patients at the primary care level). The result of this will be to move the management of OIs closer to the patient while ensuring that referral links with higher-level facilities and care is cultivated.
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Октябрь 2017
Русский
Рекомендации EACS 9.0
The guidelines are aimed at clinical professionals directly involved with and responsible for the care of adults with HIV infection, and at community advocates responsible for promoting the best interests and care of HIV-positive adults. They should be read in conjunction with other published BHIVA ...guidelines.
The 2016 interim update to the 2015 BHIVA antiretroviral guidelines has been published online to include tenofovir-alafenamide/emtricitabine as a preferred NRTI backbone for first-line therapy. Changes were based on new data and the consensus opinion of the writing committee. All changes to the guideline are highlighted and include updates to the chronic kidney disease and bone disease sections of special populations and some small changes to managing virological failure.
The 2019 interim statement provides updated advice on treatment with two-drug regimens
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Diagnosis and Treatment Outcomes of Tuberculosis in Relation to Gender and HIV Status in South Benin
Journal of Tuberculosis Research, 2017, 5, 189-200
Background: In Benin, little is known about the influence of both gender and
HIV-status on diagnostic patterns and treatment outcomes of Tuberculosis
(TB) patients. Objective: To assess whether differences in gender and HIV
status affect diagn...ostic patterns and treatment outcomes of TB patients. Methods:
Retrospective cohort study of patients registered in 2013 and 2014 in
the three largest TB Basic Management Units in south Benin. Results: Of 2694
registered TB patients, 1700 (63.1%) were male. Case notification rates were
higher in males compared with females (96 vs 53/100,000 inhabitants). The
male to female ratio was 1:1 in HIV positive patients, but was 2:1 among HIV
negative cases. In HIV-positive patients, there were no differences in TB types
between men and women. In HIV-negative patients, there were significantly
higher proportions of females with clinically diagnosed pulmonary TB (p =
0.04) and extrapulmonary TB (p < 0.001). Retreatment TB was 4.65 times
higher amongst males compared with females. For New bacteriologically confirmed
pulmonary TB, no differences were observed in treatment outcomes
between genders in the HIV positive group; but significantly more unfavorable
outcomes were reported among HIV negative males, with higher rates of
failure (p < 0.001) and loss-to-follow up (p = 0.02). Conclusion: The study
has shown that overall TB notification rates were higher in males than in females
in south Benin, with more females co-infected with HIV. Unfavorable outcomes were more common in HIV-negative males.
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Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions.
Gr...am-negative bacteria, such as Klebsiella pneumoniae and Escherichia coli, can cause severe and often deadly infections that pose a particular threat for people with weak or not yet fully developed immune systems, including newborns, ageing populations, people undergoing surgery and cancer treatment.
The report highlights a worrying gap in activity against the highly resistant NDM-1 (New Delhi metallo-beta-lactamase 1), with only three antibiotics in the pipeline. NDM-1 makes bacteria resistant to a broad range of antibiotics, including those from the carbapenem family, which today are the last line of defence against antibiotic-resistant bacterial infections.
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Research Article
PLOS Medicine | DOI:10.1371/journal.pmed.1002253 April 4, 2017
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