The recommendations in these guidelines promote the use of simple, non-invasive diagnostic tests to assess the stage of liver disease and eligibility for treatment; prioritize treatment for those with most advanced liver disease and at greatest risk... of mortality; and recommend the preferred use of nucleos(t)ide analogues with a high barrier to drug resistance (tenofovir and entecavir, and entecavir in children aged 2–11 years) for first- and second-line treatment. Recommendations for the treatment of HBV/HIV-coinfected persons are based on the WHO 2013 Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection, which will be updated in 2015.
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Summary of lessons learned
Self-imposed quarantine has proved less problematic.
The timely and reliable delivery of resources (e.g. food/water) and expertise (e.g. contact tracing/safe and dignified burials) is essential to ensure cooperation and deter quarantine violation.
The commun...ities’ understanding of the benefits of quarantine and its role in stopping the outbreak is essential.
Coercion is counterproductive.
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National Operational Guidelines
NATIONAL TUBERCULOSIS AND LEPROSY PROGRAMME
PLoS Curr. 2014 Aug 29;6. pii: ecurrents.dis.17ad1f98fb85be80785d0a81ced6a7a6. doi: 10.1371/currents.dis.17ad1f98fb85be80785d0a81ced6a7a6.
These guidelines – an update to the World Health Organization’s 2015 publication Consolidated strategic information guidelines – present a set of essential aggregate indicators and guidance on... choosing, collecting and systematically analysing strategic information to manage and monitor the national health sector response to HIV.
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Q 1: Are antidepressants (Tricyclic Antidepressants (TCA) and Selective Serotonin Reuptake Inhibitors (SSRI)) better (more
effective than/as safe as) than treatment as usual (placebo) in adults with depressive episode/disorder?
Q 3: Is brief, structured psychological treatment in non-specialist health care settings better (more effective than/as safe as) than treatment as usual in people with depressive episode/disorder?
AIDS Research and Therapy 2015, 12:12 (24 April 2015)
Drugs, Diagnostics, Vaccines, Preventive Technologies, Research toward a cure, and immune-based and gene therapies in development
Caribbean Sub-regional Training Workshop. Introducing the new guidelines: Preparedness and Response for Chikungunya Virus Introduction in the Americas in the context of Dengue