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Publication Years
1226
2795
386
25
2
Category
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412
270
201
92
87
51
2
2
2
Toolboxes
359
341
276
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270
212
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124
105
101
94
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66
44
37
19
12
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7
2
All WHO essential medicines are covered in Wikipedia: https://en.wikipedia.org/wiki/WHO_Model_List_of_Essential_Medicines, and items are translated
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in several languages. Increasing the amount, quality and languages of information on essential medicines through multiple sources- Wikipedia, formularies, guidelines- will help promoting the use of essential medicines across communities
Accessed July 1 ,2019
more
The recommendations cover the level of blood pressure to start medication, what type of medicine or combination of
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medicines to use, the target blood pressure level, and how often to have follow-up checks on blood pressure. In addition, the guideline provides the basis for how physicians and other health workers can contribute to improving hypertension detection and management.
more
After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discove
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ry for HAT with special emphasis on the discovery, pre-clinical development, and operational challenges of the clinical trials of fexinidazole. The screening of the Drugs for Neglected Diseases initiative (DNDi) HAT-library by the Swiss TPH had singled out fexinidazole, originally developed by Hoechst (now Sanofi), as the most promising of a series of over 800 nitroimidazoles and related molecules. In cell culture, fexinidazole has an IC50 of around 1 µM against Trypanosoma brucei and is more than 100-fold less toxic to mammalian cells. In the mouse model, fexinidazole cures both the first, haemolymphatic, and the second, meningoencephalitic stage of the infection, the latter at 100 mg/kg twice daily for 5 days. In patients, the clinical trials managed by DNDi and supported by Swiss TPH mainly conducted in the Democratic Republic of the Congo demonstrated that oral fexinidazole is safe and effective for use against first- and early second-stage sleeping sickness. Based on the positive opinion issued by the European Medicines Agency in 2018, the WHO has released new interim guidelines for the treatment of HAT including fexinidazole as the new therapy for first-stage and non-severe second-stage sleeping sickness caused by Trypanosoma brucei gambiense (gHAT). This greatly facilitates the diagnosis and treatment algorithm for gHAT, increasing the attainable coverage and paving the way towards the envisaged goal of zero transmission by 2030.
more
Since the introduction of penicillin in the early twentieth century, antimicrobial treatments have been utilized not only in human medicine but also in veterinary care – initially to ward off diseases, prevent post-surgery infections,
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and treat sick farm animals.Global food production has intensified over the past 50 years due to economic expansion and popu-lation growth. The use of antimicrobials in agriculture – in livestock, fish farming, and even on crops – has grown as well. Antimicrobials are not only used as medicines, but are sometimes also added in low concentrations to animal feed as a way of stimulating growth.
more
For 50 patients requiring surgical care in emergency situations assuming 2 operations per patient (100 interventions)
WHO trauma and emergency surgery kit (TESK) aims to provide materials and drugs to meet the needs of 50 patients requiring surgi
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cal care in emergency situations, assuming an average of two operations per patient. This kit is intended for use by health care providers who are trained in appropriate management of emergent surgical issues and are acting within their scope of practise. It is designed for use in areas where basic levels of infrastructure exist. The composition of TESK has recently been revised in collaboration with the International Committee of the Red Cross to meet the dynamic requirements of emergency situations. In general, this kit contains oral and IV medicines including cold chain drugs and medical supplies including renewables and instruments.
WHO TESK is intended to provide the resources needed for surgical procedures in operating theatres. Some of the sub-units may be used for simpler procedures that may occur in other parts of the facility.
more
The Animal Medicines Best Practice (AMBP) programme: developed by NOAH in partnership with stakeholders along the food supply chain to improve co-ordination and consistency in approach to the responsible u
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se of medicines. Training modules are available for dairy, beef, sheep and pig farmers on the responsible use of antibiotics.
more
Chapter 16: Managing medicine selection - Key topics: the concept of essential medicines; selection of essential
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medicines and development of essential medicines lists, formularies, and treatment guidelines. - The rationale for selecting a limited number of essential medicines is that it may lead to better supply, more rational use, and lower costs.
more
Antimicrobial resistance (AMR) is a threat to human and animal health and refers to the ability of microorganisms to defy the medicines prescribed. For instance when antibiotics are used improperly,
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such as an incorrect dose, insufficient duration or wrong frequency, resistance is heightened. The misuse of antimicrobials affects their efficacy, and increasingly more infections and diseases become untreatable. Many gains made in modern medicine throughout the 20th century will be lost, making AMR a global public and animal health issue that requires concerted action. AMR and the use of antimicrobials (AMU) affect food safety and security, people’s livelihoods, as well as economic and agricultural development.
more
Using an inhaler is the most common and effective way of taking asthma medicines. If you’re NOT using your inhaler correctly, you might not be getting the full dose
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of medicine your doctor or asthma nurse prescribed because the medicine can’t reach your
lungs. Instead it might be hitting the back of your throat, orstaying on your tongue or in your mouth where it won’t help atall.
more
The National pharmaceutical policy aligns itself to the Government vision for development of the health sector, as defined in Vision 2020, the Millennium Development Goals and the Economic Development for Poverty Reduction Strategy and the National
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Health Policy. The pharmacy policy addresses, among other challenges, the establishment of functional National Medicines Regulatory Authority that will implement all the regulatory functions, lack of local manufacturing facilities, lack of pricing policy of health commodities and technologies in private sector. This policy is based on the following key priorities: the Quality assurance, accessibility and the rational use of medicines, other health commodities and technologies.
more
Key facts
- Cardiovascular diseases (CVDs) are the leading cause of death globally.
- An estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths.
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Of these deaths, 85% were due to heart attack and stroke.
- Over three quarters of CVD deaths take place in low- and middle-income countries.
- Out of the 17 million premature deaths (under the age of 70) due to noncommunicable diseases in 2019, 38% were caused by CVDs.
- Most cardiovascular diseases can be prevented by addressing behavioural risk factors such as tobacco use, unhealthy diet and obesity, physical inactivity and harmful use of alcohol.
- It is important to detect cardiovascular disease as early as possible so that management with counselling and medicines can begin.
more
Website last accessed on 14.04.2023
One of the ongoing challenges with neglected tropical diseases (NTDs) is that the discovery of medicines to
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treat them has been very slow. Current global programmes for NTDs largely depend on donated medicines, primarily to treat the world’s poorest people – most of whom live in remote rural or in deprived urban settings.
WHO recently spoke to Mr Robert J. Gyurik, who discovered albendazole in 1972. He took us through the journey that led him to develop the compound.
more
Chemoprevention is the use of medicines, either alone or in combination, to prevent malaria infection and its consequences. This publication provid
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es standardized approaches for monitoring and evaluating the efficacy of medicines used for intermittent preventive treatment of malaria in pregnancy, perennial malaria chemoprevention (formerly known as intermittent preventive treatment of malaria in infants), seasonal malaria chemoprevention and intermittent preventive treatment of malaria in school-aged children. It follows the recent release of new and updated WHO recommendations on these interventions.
more
Issue Brief 31: Antimicrobial resistance (AMR) can occur when viruses, bacteria, parasites and fungi change over time. There is no longer a response to medicines, and the infection treatment gets really difficult which increases the risk
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of a disesase spread, which can lead to severe health problems. AMR is an increasing threat to global public health worldwide that requires cross-sectional and cross-disciplinary action. It is present in every country and is spurred by several human-made factors, including over- and/or inadequate use of antibiotics, poor hygiene and infection prevention control, and excessive usage of antibiotics outside the health care sector e.g. in life stock production.
more
This is a pocket-sized manual for use by doctors, senior nurses and other senior health workers who are responsible for the care of young children at the first referral level in developing countries
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. It presents up-to-date clinical guidelines which are based on a review of the available published evidence by subject experts, for both inpatient and outpatient care in small hospitals where basic laboratory facilities and essential drugs and inexpensive medicines are available. It focuses on the inpatient management of the major causes of childhood mortality, such as pneumonia, diarrhoea, severe malnutrition, malaria, meningitis, measles, HIV infection and related conditions. It covers neonatal problems and surgical conditions of children which can be managed in small hospitals. This pocket book is part of a series of documents and tools that support the Integrated Management of Childhood Illness (IMCI).
more
Antimicrobial resistance (AMR) represents a major threat to human health with significant global economic and security implications. In 2015, WHO Member States unanimously approved a Global Action Plan to tackle AMR (GAP-AMR). The goal of GAP-AMR is
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“to ensure, for as long as possible, continuity of successful treatment and prevention of infectious diseases with effective and safe medicines that are quality-assured, used in a responsible way, and accessible to all who need them”.
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Pharmacy Toolbox
recommended
Please find all relevant guidelines and information in our new Pharmacy Toolbox.
The PHARMACY TOOLBOX is a comprehensive knowledge repository to provide its users with practical, up-to-date information on medicines and good pharmaceutical practices
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. It collates basic documents on (essential) medicines, guidelines, rational use, access, and good quality of medicines. All health workers who prescribe, handle or dispense medicines find an electronic key pharmacy knowledge hub.
more
Our target end-users are those with limited literacy. It is a challenging task to achieve success in this group as so much of what is "obvious" to those of us with good literacy skills is totally ob
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scure to those who have never had the opportunity to learn the meaning of e.g. an arrow shape and what it is meant to represent. Our pictograms have been tested mainly in our local Xhosa population, so we cannot guarantee universal generalisability (as is the case for any other pictograms). Categories in the database include Dosage and frequency; Route of administration; Additional medicine instructions; Side effects or indications; Storage of medicines; Tablets, capsules, bottles, droppers; Miscellaneous; TB-related pictograms
A common application relates to their use with medicines where they may serve to convey instructions, precautions, storage requirements, warnings, as well as medicine indication or side effects to patients or consumers. Many examples of diverse application of pictograms in the health literature have been described including health promotion materials, wound care instructions, asthma prevention and treatment, injury prevention, discharge instructions, self-care guidance, paediatric anaphylaxis plan, organ and body donation, CT scan risks and benefits, driving risks, safety symbols, decision aids for treatment, and patient-reported outcomes dashboards, amongst others.
more
The European Medicines Agency (EMA) is evaluating potential COVID-19 treatments and vaccines to enable promising medicines to reach patients as soon as possible. It is also interacting with medicine
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developers and making use of real-world data to monitor the safety and effectiveness of medicines used in patients with COVID-19.
more
You can’t cure asthma. However, you can take steps to control the disease and prevent its symptoms. For example:
-Learn about your asthma and ways to control it
-Follow your written asthma action plan
-Use
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medicines as your doctor prescribes (Here’s how to use your inhaler device)
-Identify and try to avoid things that make your asthma worse
-Keep track of your asthma symptoms and level of control
-Get regular checkups for your asthma
more
