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The Global Strategy for Tuberculosis Research and Innovation will support the efforts of governments and other stakeholders to accelerate TB research and innovation, and improve equitable access to the benefits of research. Availabl in Arabic, Chinese, English, French, Spanish and Russian
The 2020 recommendations for the programmatic management of TB preventive treatment are the first to be released under the rubric of WHO consolidated TB guidelines (Module 1 – Prevention). The WHO consolidated TB guidelines will gradually group all TB recommendations and will be complemented by ma ... more
6 July 2021. The “WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update” is the latest document replacing the one issued in 2020. Three new nucleic acid amplification test (NAAT) classes are endorsed by WHO and included in the ... more
he WHO South-East Region in 2019 accounted for nearly a million missing TB patients from the estimated incidence. Active case-finding (ACF) or systematic screening for tuberculosis is an important tool to reach out to missing TB patients. When appropriately implemented, the activity is cost effectiv ... more
The Compendium of data and evidence-related tools for use in TB planning and programming was developed as a companion document to the People-centred framework for tuberculosis programme planning and prioritization – user guide, published by the World Health Organization (WHO) ... more
El manual está orientado para dar a conocer las directrices y métodos para evaluar la calidad y confiabilidad de las baciloscopías que realizan los laboratorios. Aunque estos métodos o están concebidos para verificar el diagnóstico de cada paciente, el procedimiento de identificar y corregir l ... more
Final Survey Report
WHO's Health in the Green Economy sector briefings examine the health impacts of climate change mitigation strategies considered by the Intergovernmental Panel on Climate Change in their Fourth Assessment Report.
Tuberculosis (TB) is the deadliest infectious disease in most low- and middle-income countries, claiming more than 4,000 lives each day. The unprecedented COVID-19 pandemic has seriously impacted people with pre-existing health conditions. People with TB are usually more vulnerable to other infectio ... more
The guide is suitable and can be used for the following audiences: 1. nurses and other trained healthcare workers who can use this manual as a self-study tool and then incorporate its guidance into their practice; 2. governmental and non-governmental employers of lay and professional TB treatment ... more
The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible TB, a new option for the treatment of TB meningitis, the use of bedaquiline and delama ... more
The practical guidance in the operational handbook aims to inform the development or revision of national policies and related implementation guidance on the management of TB in children and adolescents under programmatic circumstances and at different levels of the health system. The operational ha ... more
Parte I - Baciloscopía
Panam Salud Publica. 2021;45:e22. https://doi.org/10.26633/RPSP.2021.22
In Paraguay, 1.8% of the population are indigenous people. The Maká community 29 mainly live in urbanized areas in the Central Region. This study focuses on the epidemiology 30 of tuberculosis (TB) among indigenous Maká and the non-indigenous people living in the 31 Central Region, the biggest ... more
El objetivo de este artículo es analizar las condiciones de acceso a servicios de salud de las personas con tuberculosis en América Latina y el Caribe (ALC), reflexionando desde la bioética sobre los aspectos de salud pública implicados. Se realizó una revisión documental del contexto de la ... more
Health Policy and Planning, Volume 35, Issue 1, February 2020, Pages 47–57, https://doi.org/10.1093/heapol/czz122 Colombia has an underreporting of 30% of the total cases, according to World Health Organization (WHO) estimations. In 2016, successful tuberculosis (TB) treatment rate was 70%, and t ... more
Buruli ulcer caused by Mycobacterium ulcerans is a neglected tropical disease characterized by extensive ulceration involving predominantly the upper and lower limbs of patients. The disease is common in rural tropical communities in West and Central Africa, where access to proper health care is lim ... more
The Practical manual on laboratory strengthening, 2022 update provides practical guidance on implementation of WHO recommendations and best practices for TB laboratory strengthening. It is an updated version of the GLI Practical Guide to Laboratory Strengthening published in 2017 and provides the la ... more
The WHO standard: Universal access to rapid tuberculosis diagnostics sets benchmarks to achieve universal access to WHO-recommended rapid diagnostics (WRDs), increase bacteriologically confirmed tuberculosis and drug resistance detection, and reduce the time to diagnosis. WHO-recommended rapid diagn ... more
The Africa Centres for Disease Control and Prevention (Africa CDC) Biosafety and Biosecurity Initiative was launched by the Africa CDC in April 2019 with the aim of strengthening the African Union (AU) Member States’ biosafety and biosecurity systems and enabling them to comply with national and i ... more
In a prospective cohort study in Bangwe primary care clinic, Blantyre, Malawi, all adults (18 years or older) presenting with an acute illness were screened for TB symptoms (cough, fever, night sweats, weight loss). Demographic characteristics were linked to exit interview by fingerprint bioidentifi ... more
Malawi is a landlocked country with a surface area of 118,484 km2. Administratively, the country is divided into three regions, namely the Northern, Central and Southern regions. The country has 28 districts, which are further divided into traditional authorities (TA) ruled by chiefs. The TAs are su ... more
This publication is an updated version of the Management of Tuberculosis and HIV Coinfection clinical protocol released in 2007 by the WHO Regional Office for Europe. It is intended for all health care workers involved in preventing, diagnosing, treating and caring for people living with TB and HIV ... more
Advising principles. The purpose of this document is to support competent authorities in charge of IHR implementation to improve national capacities for the prevention, detection and control of events, by strengthening communications and coordination between points of entry and the national health s ... more
Operational Guidelines for Planning and Implementation in District Hospitals
Version: 24 April 2018
The skin of a patient is the first and most visible structure of the body that any health-care worker encounters during the course of an examination. To the patient, it is also highly visible, and any disease that affects it is noticeable and will have an impact on personal and social well-being. Th ... more
Guidelines for the Management of common childhood Illness. 2nd edition These guidelines focus on the management of the major causes of childhood mortality in most developing countries, such as newborn problems, pneumonia, diarrhoea, malaria, meningitis, septicaemia, measles and related conditions, ... more
hese are two parallel guidelines, one for small hospitals and another one for large hospitals. In view of heavy burden of malaria and prevalence of drug resistant falciparum malaria in the South-East Asia Region, the guidelines were developed for use by medical personnel who treat severe malaria pat ... more
Background book on Management of the Child with a Serious Infection or Severe Malnutrition
This Handbook, an updated edition of the Management of Severe Malaria, provides new and revised practical guidance on the diagnosis and management of severe malaria.
Case Management; Guide for Tutors

District Laboratory Practice in Tropical Countries Part-2

Cheesbrough, M. Cambridge University Press (2006) C4
Guide for tutors

Guidelines for Clinical and Operational Management of Drug-Resistant Tuberculosis

José A. Caminero International Union Against Tuberculosis and Lung Disease (The Union) (2013)
Integrated Management of pregnancy and childbirth
Training Module on Malaria
2nd edition. Training module on malaria control
A global Review of evidence and practice
The goal of this addendum is to help management and staff 
minimize the risk of TB transmission at facilities in resource limited settings in which a.) HIV-infected persons receive diagnosis, care, treatment, 
and/or support, and b.) there is a high prevalence of HIV infection, both known 
and ... more

National Guidelines For the Management of HIV and AIDS

Ministry of Health and Social Welfare, Tanzania Ministry of Health and Social Welfare, Tanzania (2015) CC
5th edition.
The development of this target product profile (TPP) was led by the WHO Department of Control of Ne- glected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was ... more
The updated List of Essential Diagnostics contains 46 general tests that can be used for routine patient care as well as for the detection and diagnosis of a wide array of disease conditions, and 69 tests intended for the detection, diagnosis and monitoring of specific diseases. The List is divid ... more
Accessed at March 2014
The manual is written for clinicians working at the district hospital (first-level referral care) who diagnose and manage sick adolescents and adults in resource constrained settings. It aims to support clinical reasoning, and to provide an effective clinical approach and protocols for the managemen ... more
The guidelines acknowledge that overcrowding, unhygienic conditions and high inmate turn over contribute to the spread of infectious diseases within correctional facilities. The document states that voluntary HIV counselling and testing must be offered to all inmates when they enter facilities, duri ... more
Successes and lessons
Plos Neglected Tropical Diseases 8(11): e3229 (20 November 2014)
Fourth Edition
Primary Care: The Community Health System
Moving towards equity and quality
4th edition. A manual for clinics, community health centers and district hospitals
The training focuses on building the capacity of health care workers at the primary and secondary level to address and manage TB in children.

HIV/AIDS Diagnostics Technology Landscape - 5th edition

Unitaid; World Health Organization (2015) C_WHO
October 2015
2nd edition
Standard Treatment Guideline
Standard Treatment Guideline
Guidelines for Primary, Secondary and Tertiary Level Care
Malawi Integrated Guidelines and Standard Operating Procedures for Providing HIV Services. 3rd edition 2016