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Cheema B., A. Westwood

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Children & AIDS

Children's HIV Services (Be their key to life)

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Cholera Secretariat Zimbabwe

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Circulation

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Clubfoot Care for Kenya

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Common Sense for Drug Policy

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Cureus

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et al. (Джеймса Баера

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State of Libya

Statistics Indonesia (Badan Pusat Statistik—BPS), National Population and Family Planning Board (BKKBN), and Kementerian Kesehatan (Kemenkes—MOH), and ICF International

Statistics Indonesia (Badan Pusat Statistik—BPS), National Population and Family Planning Board (BKKBN), Kementerian Kesehatan (Kemenkes—MOH), and ICF International

Statistics Sierra Leone, ICF International, et al.

Statistics Sierra Leone, Ministry of Health and Sanitation Sierra Leone, ICF International

Stefan Mauss, Thomas Berg, Jürgen Rockstroh et al.

Stephen M. Ellis

Stevens, Gretchen

Stoddard, Abby

Stone, D.

Stop TB Partnership to reach

Strategic Executive Group and Partners

Stree Shakti-The Parallel Force, United Nations Population Fund (UNFPA)

Strengthening Pharmaceutical Systems (SPS) Program

STRIVE

STUK

Suchona Foundation

Sue George, John Dada, Kolawole Maxwell et al.

Sundar, S.

Susanne Habetha, Sabrina Bleich, Christoph Sievers, Ursula Marschall, Jörg Weidenhammer, Jörg M. Fegert

Susanne Jaspars and Hisham Khogali

Sustainable Development Solutions Network

Sustainable Energy for All

Svitanok

Swan

Syrian American Medical Society

Syrian American Medical Society (SAMS)

T. Chitashvili, S. Holschneider, O. Annie Clark

T. D. Benton

T. Frieden

T. Groshkova

T. Jones and J. Bedford

T. Khumalo

T. Maimakov, L. Sadykova, Z. Kalmataeva, et al.

T. N. Saw

T. Nakari

T. Rhodes

T. Welsh

Tabitha Hrynick, T.

Tajikistan Network of Women living with HIV (Public Organization)

TAJSTAN

Takarinda, Kudakwashe C., Lydia K. Madyira, Mutsa Mhangara, Victor Makaza, Memory Maphosa, Simbarashe Rusakaniko, Peter H. Kilmarx, Tsitsi Mutasa-Apollo, Getrude Ncube, and Anthony D. Harries

Tambo, Ernest

Tania Barham, Randall Kuhn, Jane Menken et al.

Tanzania Commission for AIDS (TACAIDS)

Tanzania Commission for AIDS (TACAIDS), Zanzibar AIDS Commission (ZAC), National Bureau of Statistics (NBS), Office of the Chief Government Statistician (OCGS), and ICF International

Tanzania Food & Drugs Authority (TFDA)

Tanzania Food and Nutrition Centre

Tanzania Ministry of Health, Community Development, Gender, Elderly and Children.

Tapash Roy et al.

Tapash Roy, Lucy Marci, Rashed H. Chowdhury, Kaosar Afsana, Henry Perry

Tasker, A.

TB Care

TB Care II

TB/CTA

Tchatchouang, S.

TDH

TDR

TDR Program

Tearfund

Tefera, S.

Teferi, M.

Teh DHS Program

Terre des hommes, Save the Children, Plan International, SOS Children's Villages International, World Vision, ChildFund Alliance

Terzic, C.P. et al.

Than Tun Sein

The Alliance for Child Protection in Humanitarian Action, Network for Education

The Alliance for children protection in humanitarian action

The Asia Foundation

The Cameroon Academy of Sciences

The Center For Disease Dynamics, Economics & Policy

The Center for HIV Law Policy

The DHS Program ICF Rockville, Maryland, USA

The Economic Commission for Africa (ECA)

The Economist Intelligence Unit Limited

The Estonian Ministry of Justice

The Ethiopian Public Health Institute, Federal Ministry of Health Ethiopia

The Federal Democratic Republic of Ethiopia

The fight against fake drugs by NAFDAC in Nigeria Olike Chinwendu

The Georg Institute for Global Health India

The Global Coalition on Women and AIDS

The Global Public Private Partnership for Handwashing

The Government of Malawi

The Government of Uganda

The Governments of Burkina Faso and Norway, the Bill & Melinda Gates Foundation, and the World Bank Group

The Health & Education Advice & Resource Team (HEART)

The Indonesian Society of Endocrinology Task Force on Thyroid Diseases

The International Journal of Psychosocial Rehabilitation

The Johns Hopkins and the International Federation of Red Cross and Red Crescent Societies

The Johns Hopkins Center for Humanitarian Healt

The Kitchener Downtown Community Health Centre, et al.

The Lancet Commissions

The Lancet healthy Longevity

The Lancet Microbe

The Lancet Regional Health - Americas

The MEDBOX Team

The Ministry of Education, Science, Technology and Sports (MoESTS), Uganda

The Ministry of Health

The National Child Traumatic Stress Network

The National Institute For Communicable Diseases, South Africa

The New England Journal of Medicine

The New York Academy of Medicine, Drug Policy Alliance

The Partnership for Maternal, Newborn & Child Health

The Population Council

The Republic of Malawi

The Republic of Montenegro

The Republic of the Union of Myanmar

The Republic of the Union of Myanmar, Ministry of Health, Department of Health, Child Health Division

The Republic of the Union of Myanmar, Ministry of Health, Department of Health, National AIDS Programme

The Republic of the Union of Myanmar, Ministry of Health, Department of Health, National Tuberculosis Programme

The Review on Antimicrobial Resistance

The ROTA Council

The Royal Society Publishing

The Sentinel Project

The SMERU Research Institute, UNICEF

The South African Medical Journal

The Southern African HIV Clinicians Society (SAHCS)

The Sphere Project

The Strengthening High Impact Interventions for an AIDS-free Generation (AIDSFree) Project

The Uganda Gazette

The William J. Clinton Foundation

The World Bank

Theo Smart

THL

Three Millennium Development Goal Fund (3MDG)

Ties Boerma, Colin Mathers, Carla AbouZahr, Somnath Chatterji, Daniel Hogan and Gretchen Stevens

Ties Boerma, Jennifer Requejo, Cesar Victora et al.

Tigray Health Bureau

Tirados, I.

Titaley, C.R.

Tom Corsellis and Antonella Vitale

Tracy Pugh, Julie Netherland, Ruth Finkelstein

Training NRM School of Medicine

Trials

Tromp, J.

Tufts University

Tufts University, Oxfam

Turco, J.V. et al.

U N Population Fund

U.S. Department of Health & Human Services

U.S. Department of Health and Human Services

U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry (ATSDR)

U.S. Department of Health and Human Services, Office on Women’s Health

U.S. Department of Health and Human Services.

U.S. Food & Drug Administration

U.S. Global Malaria Coordinator

U.S. President's Emergency Plan for AIDS Relief

U.S. Presidents Malaria Initiative

U.S. President’s Malaria Initiative (PMI), CDC, USAID, et al.

Uganda Aids Commission, Republic of Uganda

Uganda Government (OPM)

Uisso, C.

UKAid, CRS

Umbas, R., S. Hardjowijoto, F. Safriadi, et al.,

UN Children's Fund and Government of the United Republic of Tanzania

UN Development Programme, UN Mission for Ebola Emergency Response

UN Educational, Scientific and Cultural Organization

UN Educational, Scientific and Cultural Organization UNESCO

UN Enivronemnt Programme UNEP

UN Environment

UN High Commissioner for Refugees, Protection Cluster, Health Cluster

UN Human Rights Council

UN Mission for Ebola Emergency Response

UN Office for the Coordination of Humanitarian Affairs, Government of Madagascar, UN Country Team in Madagascar

UN Office for the Coordination of Humanitarian Affairs, UN Country Team in Peru

UN Office for the Coordination of Humanitarian Affairs, UN Country Team in Yemen

UN Office of the High Commissioner for Human Rights, UN Mission in South Sudan

UN Population Fund

UN Population Fund, UN High Commissioner for Refugees, Women's Refugee Commission

UN RC Malawi

Un Security Council

UNAIDS (Joint United Nations Programme on HIV/AIDS

UNAIDS | GAMET

UNAIDS, The National AIDS Authority (NAA)

UNCT Malawi

UNCT Mozambique

UNDP (Empowered lives, Resilient nations)

UNESCO

UNFPA-UNICEF Joint Programme on Female Genital Mutilation

UNHCR The UN Refugee Agency

UNHCR United Nations High Commissioner for Refugees

UNHR

UNICEF Bangladesh

UNICEF Indonesia

UNICEF ROSA

Unicef, et al.

UNICEF, WHO, UNESCO, UNFPA, UNDP, UNAIDS, WFP

UNICEF, World Health Organisation

UNICEF, World Health Organisation (WHO)

UNIECF

UNIFEM

Union for International Cancer Control (UICC)

UNISDR

Unitaid

Unitaid (Innovation in Global Health)

UNITE FOR DIABETES PHILIPPINES

United Nations (UN)

United Nations agencies, the World Bank and the European Commission

United Nations and Partners

United Nations Children's Fund (UNICEF) & United States Agency for International Development (USAID)

United Nations Children's Fund (UNICEF) & World Health Organisation (WHO)

United Nations Children’s Fund (UNICEF), Bangladesh

United Nations Children’s Fund UNICEF

United Nations Development Programme (UNDP) and the Oxford Poverty and Human Development Initiative (OPHI)

United Nations ECLAC

United Nations Economic Commission for Europe

United Nations Educational, Scientific and Cultural Organization (UNESCO)

United Nations Educational, Scientific and Cultural Organization Mahatma Gandhi Institute of Education for Peace and Sustainable Development (UNESCO MGIEP)

United Nations General Assembly

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United Nations Institute for Disarmament Research (UNIDIR)ESEARCH

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United Nations Mission in the Republic of South Sudan (UNMISS)

United Nations of Human Rights

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United Nations Office for the Coordination of Humanitarian Affairs OCHA

United Nations Office on Drugs and Crime (Regional Office for Central Asia)

United Nations Office4 on Drugs and Crime

United Nations on Drugs and Crime

United Nations Population Fund (UNFPA)

United Nations Population Fund UNFPA

United Nations Population Fund UNPF

United Nations Secretary-General

United Nations UN

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United Nations, The World Bank, European Union and African Development Bank

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United States Agency for International Development USAID

United States Department of Health and Human Services

United States Government Zambia Interagency Team

Uniting Combat Negleceted Tropical Diseases

Uniting To Combat NTDs

Univ. Zagreb

University of Cambridge shelterproject

University of Jordan

University of Kwa-Zulu Natal

University of Notre Dame Australia

University of Oslo

University of Oxford

University of Zambia, et al.

University Teaching Hospital,

Universtität Innsbruck

UNMEER

UNODC

UNODC (United Nations Office on Drugs and Crime)

UNSP

Uppsala Universitet

UpToDate

US Agency for International Development

US Aid, UK Aid, UNICEF

US Department of Homeland Security, US Department of Health and Human Services

US Embassy Freetown

US President's Malaria Initiative

US-China Education Review

USAI

USAID (U.S. President’s Emergency Plan for AIDS Relief)

USAID ASSIST Project

USAID From the American People (Health Care Improvement Project)

USAID, BASICS

USAID, CapacityPlus & PEPFAR

USAID, core group, PLAN

USAID, Health Policy Project

USAID, Health Systems 20

USAID, MCHIP

USAID, MOH (Nepal)

USAID, Philippine Statistic Authority

USAID, SIAPS

USAID, Stop TB Partnership

USAID, Strengthening Pharmaceutical Systems SPS

USAID, Synergie Project

USAID, TBCARE I, TBCARE II

USAID, UNICEF, UNFPA et al.

USAID/E&E/DGST, Creative Associates International & JBS International

V. Künzel and L.Schäfer

V. Nankabirwa , J. K. Tumwine, O. Namugga, et al.

V. Oakeshott

V. Parikh

V. Simms

V. Tucci

Vaduganathan, M.

Vaidyanathan, A.

Valdoleiros, S. R.

Vale, GA et al.

Valerie Karr et al.

Van de Sande, W.

Van Katwyk, S. R.

Varkey, B.

Vaughan, P.

Verjeen, M.

Veronese, Vanessa et al.

Verver, S.

Victoria Simpkin, LauraSuhlrie, Alastair Wood et al

Vigaud-Walsh, Francisca

Ville de Goyet, Claude de

Vitamin Angels

Vocies

W.Cheung

W.K. Townend

Waage, J.

WACD

WACD West Africa Comission on Drugs

Wado, Yohannes Dibaba

Waqas Ashfaq Qureshi

War Child

War Child International, Women's Refugee Commission

War Trauma Foundation, Ahfad University for Women

Warrell, D.

Washington, DC: Palladium, Health Policy Plus

Wasif Malik, M.

Water Partnership Program

Watkins, J:W.

Weerawat Manosuthi, Sumet Ongwandee, Sorakij Bhakeecheep et al.

Weese, J.

Welburn S. C., Beange I. et al

Wendy Ager, Yvonne Sliep and Reem Ibrahim Ahmed, et al.

Wenjuan Wang, Rebecca Winter, Lindsay Mallick, Lia Florey, Clara Burgert-Brucker, and Emily Carter

Wenzel, S. E.

Wesern Cape Government, South Africa

Western Pacific Region

Western Pacific Region)

WFP World Food Programme

WHO Africa

WHO et al.

WHO Framework Convention on Tobacco Control

WHO Regional Office for Africa

WHO Regional Office for Europe

WHO South Sudan

WHO Tecnical Advisory Group and FIND

WHO, et al.

WHO, International Cooperation of Midwifes

WHO, London School of Hygiene & Tropical Medicine, and the International Trachoma Initiative

WHO, Pan American Health Organization

WHO, Path, et al.

WHO, THE END TB STRATEGY

WHO, UNFPA, and Escuela Andaluza de Salud Publica Consejeria de Salud

WHO, UNICEF, Countdown to 2015

WHO, USAID, UNICEF

WHO, WEDC, and IWMI

WHO/International Society of Radiology

Wiedenmayer, K. et al.

Wilkinson, S.

Williams, D. et al.

Williams, Phoebe CM.

Willy McCourt, W. & Awases, M.

Winter, Rebecca, Akinlo, Ambrose, and Lia Florey

Winter, Rebecca, Thomas Pullum, Anne Langston, Ndicunguye V. Mivumbi, Pierre C. Rutayisire, Dieudonne N. Muhoza, and Solange Hakiba

Wirtz, Andrea L.

Wisner, B

Wolrd Innovation Summir ofr Health WISH

Wolters Kluwer Health

Wolters Kluwer Health, Inc.

Wonca International Classification Committee (WICC)

Wood MC, DePaolo, F, Whitaker RD

Word Health Organization WHO

Word Health Organization/ Regional Office of South-East Asia

World Bank Group

World Bank Group, and World Health Organization WHO

World Confederation for Physical Therapy

World Diabetes Foundation

World Federation for Mental Health

World Food Programme, UNICEF

World Health Organisation (WHO) Country Office for Nepal

World Health Organisation (WHO) Regional Office for Africa

World Health Organisation (WHO), Regional Office for Eastern Management

World Health Organisation (WHO), USAID, The Global Fund, et al.

World Health Organisation Zimbabwe

World Health Organization WHO

World Health Organization WHO - Regional Office Africa

World Health Organization & Pan American Health Organization

World Health Organization ( WHO Regional Office for Africa)

World Health Organization (Africa)

World Health Organization (Pacific Region)

World Health Organization (South East Asia Region

World Health Organization (Western Pacific Region)

World Health Organization (WHO) - Regional Office for South-East Asia

World Health Organization (WHO) and DOH Philippines

World Health Organization (WHO) and InterAgency Standing Committee (IASC)

World Health Organization (WHO) and InterAgency Standing Committee (IASC), Save the Children, et al.

World Health Organization (WHO) Regional Office for the Eastern Mediterranean

World Health Organization (WHO), Country Office for Myanmar

World Health Organization (WHO), Department of Mental Health and Substance Abuse

World Health Organization (WHO), International Pharmaceutical Federation (FIP)

World Health Organization (WHO), Ministry of Health, DR Congo

World Health Organization (WHO), Myanmar, Ministry of Health

World Health Organization (WHO), Regional Office for South-East Asia

World Health Organization (WHO), Regional Office for the Western Pacific

World Health Organization (WHO), The Global Fund, Gavi et al.

World Health Organization (WHO), the United Nations Children’s Fund (UNICEF)

World Health Organization (WHO)

World Health Organization - Regional Office for Europe

World Health Organization - Regional Office South-East Asia

World Health Organization Africa Region

World Health Organization WH=

World Health Organization WHO and International Atomic Energy Agency IAEA

World Health Organization WHO and Internationl Federation of the Red Cross ICRC

World Health Organization WHO and World Intellectual Property Organization

World Health Organization WHO Team Control of Neglected Tropical Diseases

World Health Organization WHO, CDC, UNHCR

World Health Organization WHO, IFRC

World Health Organization WHO, Regional Office Africa

World Health Organization WHO, Regional Office for Eastern Mediterranen

World Health Organization WHO, Regional Office for Europe

World Health Organization WHO, Regional Office for Europe, et al.

World Health Organization WHO, SAGE

World Health Organization WHO, SEARO

World Health Organization WHO, Stop TB

World Health Organization WHO, UNICEF

World Health Organization, Health Cluster

World Health Organization, ISDR, EU

World Health Organization, Regional Office for Africa. Ministry of Health, Botswana

World Health Organization, Regional Office for South-East Asia

World Health Organization, Regional Office for South-East Asia, Health Situation and Trend Assessment Unit of Health System Department

World Health Organization, Regional Office for the Americas

World Health Organization, Regional Office for the Western Pacific

World Health Organization, Regional Office South-East Asia

World Health Organization, South-East Asia

World Health Organization, UN High Commissioner for Refugees

World Health Organization, WASH Cluster, Health Cluster

World Health Organization, Western Pacific

World Health Organization, Western Pacific Region

World Health Organization, World Heart Federation, World Stroke Organization

World Meteorological Organization

World Organisation for Animal Health, World Health Organization (WHO), Food and Agriculture Organization (FAO)

World Palliative Care Alliance

World Vision

World Vision Singapore

WRH

Wright J.E., Werkman M., Dunn J.C. et al

Wright, J.

WTO, WHO, WIPO

Y. Arafat, R.Kabir, A.A.Masud

Y. M. F. Moreno

Y. M. Saw

Y. Tabi

Y.-H. Jin

Yale, G.

Yebyo, Henock G., Mussie A. Gebreselassie, and Alemayehu B. Kahsay

Yimer, G. et al.

Young, H., Marshak, A.

Yusuf, S.

Yvonne Bonomo, Cornelius Goos, John Howard et al.

Z. T. Gavry

Z. Z. Aunga

Z.-S. Cheng

Zachary, Blake, Zhuzhi Moore, and Pav Govindasamy

Zambia Medicines Regulatory Authority (ZAMRA)

Zambia Ministry of Health, National Food and Nutrition Commission and Food and Nutrition Technical Assistance III Project (FANTA)

Zambia National Public Health Institute

Zanzibar AIDS Commission (ZAC)

Zaw Win

Zellmann, H.

Zerbini E. De Sandro j., et al.

Zida, A.

Zimbabwe National Statistics Agency (Z IMSTAT) and ICF International. 20

Zimbabwe National Statistics Agency and ICF International

Айме Меос, Ану Суси, Эвели Месикяпп et al.

АНО «Наш Солнечный мир», Международная ассоциация Autism-Europe

Всемирная организация здравоохранения (ВОЗ)

Всемирная организация здравоохранения (Европа)

Детский фонд Клиника Тартуского университета, Клиника Тартуского университета et al.

Дженнифер Батлер

Джорджа Айалы

Е.А. Катунина, Ю.Н. Бездольный

Назим Агазаде, Ирина Михайловна Никольская, Игорь Валерьевич Добряков et al.

пер. с англ. М. Шихиревой, Международная ассоциация Autism-Europe

Российский государственный медицинский университет им. Н.И. Пирогова Кафедра неврологии и нейрохирургии лечебного факультета д.м.н., доцент Е.А. Катунина, к.м.н. Ю.Н. Бездольный

Сорос-Кыргызстан

Союз охраны психического здоровья, Issa, world council for psychotheraphy et al.

Фонд Организации Объединенных Наций в области народонаселения

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Adolescent HIV Care and Treatment: A Training Curriculum for Health Workers . Module 9 Trainer Manual

ICAP; CDC; University Teaching Hospital, et al. (2011)

Prevention and Treatment of Tobacco Use: JACC Health Promotion Series

Kalkhoran, S.; Benowitz, N.L.; Rigotti, N.A. (2018) CC

Tobacco use is the leading preventable cause of death worldwide and is a major risk factor for cardiovascular disease (CVD). Both prevention of smoking initiation among youth and smoking cessation among established smokers are key for reducing smoking prevalence and the associated negative health co ... more

Standard treatment Guidelines & Essential Medicine List. National essential medicines list for Odisha

HEALTH & FAMILY WELFARE DEPARTMENT GOVERNMENT OF ODISHA (2014) C1

Accessed at 25.03.2014

A triple-drug treatment regimen to accelerate elimination of lymphatic filariasis: From conception to delivery

G. J. Weil; Jacobson, J. A.; King J. D. International Health (2020) CC

The Global Programme to Eliminate Lymphatic Filariasis (LF) is using mass drug administration (MDA) of antifilarial medications to treat filarial infections, prevent disease and interrupt transmission. Almost 500 million people receive these medicat ... more

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Education and Community Engagement is integral to our mass Vaccination Projects

Mission Rabies (2023) CC

Children are at high risk of dog bites and contracting rabies. Forty percent of reported rabies cases worldwide are children under the age of fifteen. In our project areas, the proportion of children dying is often even higher. Rabies most often persists in poor communities and rural regions of deve ... more

Guideline for Preventive Chemotherapy for the Control of Taenia solium Taeniasis

Pan American Health Organisation PAHO (2021) C_WHO

The larval stage of the parasite Taenia solium can encyst in the central nervous system causing neurocysticercosis, which is the main cause of acquired epilepsy in the countries in which the parasite is endemic. Endemic areas are those with the presence (or likely presence) of the full life cycle of ... more

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Disaster Risk Management for Health MASS CASUALTY MANAGEMENT

World Health Organization (2011)

The many faces of diabetes. Is there a need for re-classification? A narrative review

Sakran, N.; Graham, Yiitka.; Pintar, T.; et al. BMC Endocrine Disorders Volume 22 Article Number 9 (2022) CC

The alarming rise in the worldwide prevalence of obesity and associated type 2 diabetes mellitus (T2DM) have reached epidemic portions. Diabetes in its many forms and T2DM have different physiological backgrounds and are difficult to classify. Bariatric surgery (BS) is considered the most effective ... more

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Guidance on temporary malaria control measures in Ebola-affected countries

World Health Organization (2014)

Malaria is a prevalent cause of febrile illnesses in areas with high transmission, and its clinical presentation overlaps with initial signs of Ebola disease. For this reason, the effectiveness of the Ebola response in Guinea, Liberia and Sierra Leone can be optimized through the deployment of targe ... more

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Safety in administering medicines for neglected tropical diseases. Online Course

Open WHO; World Health Organization WHO (2022) C_WHO

This course is based on the Manual on Safety in Administering Medicines for Neglected Tropical Diseases which provides practical tools, training modules and jobs aids to further improve the planning, preparation, and monitoring of safe administration of NTD medicines.

Rethinking the Top-Down Approach to Schistosomiasis Control and Elimination in Sub-Saharan Africa

Onasanya A. et al. (2021) CC

The control and elimination of schistosomiasis have over the last two decades involved several strategies, with the current strategy by the World Health Organization (WHO) focusing mainly on treatment with praziquantel during ... more

African regional progress and status of the programme to eliminate lymphatic filariasis: 2000–2020

Deribe K., Bakajikaa D. K., Zourea H. MG. et al The royal society of tropical medicine and hygiene (2021) C2

To eliminate lymphatic filariasis (LF) by 2020, the World Health Organization (WHO) has launched a campaign against the disease. Since the launch in 2000, significant progress has been made to achieve this ambitious goal. In this article we review the progress and status of the LF programme in Afric ... more

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Keeping communities at the centre of efforts to eliminate lymphatic filariasis: learning from the past to reach a future free of lymphatic filariasis

Krentel, A.; Gyapong, M.; McFarland, D.A.; Ogundahunsi, O.; Titaley, C.R.; Addiss, D.G. Oxford Academic - International Health (2021) CC

Since the launch of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) in 2000, more than 910 million people have received preventive chemotherapy for lymphatic filariasis (LF) and many thousands have received care for chronic manifestations of the disease. To achieve this, millions of c ... more

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Integrated community-based intervention for urinary schistosomiasis and soil-transmitted helminthiasis in children from Caxito, Angola

Lemosa, M.; Fançonya, C.; Moura, S. et al The royal society of tropical medicine and hygiene (2020) C2

Schistosomiasis and soil-transmitted helminths (STH) infections are major public health problems. We aimed to study the 6-mo impact of mass drug administration with praziquantel and albendazole on urinary schistosomiasis and STH.We examined children ... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO ... treatment guidelines for helminth infections are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

An open label, block randomized, community study of the safety and efficacy of coadministered ivermectin, diethylcarbamazine plus albendazole vs. diethylcarbamazine plus albendazole for lymphatic fila

JambulingamI P. , KuttiattI V.S., Krishnamoorthy K. et al (2021) C2

Better drug regimens for mass drug administration (MDA) could accelerate the Global Programme to Eliminate Lymphatic Filariasis (LF). This community study was designed to compare the safety and efficacy of MDA with IDA (ivermectin, diethylcarbamaz ... more

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Estimating the population at risk with soil transmitted helminthiasis and annual drug requirements for preventive chemotherapy in Ogun State, Nigeria

Mogaji H.O., Johnson O.O. , Adigun A.B. et al Nature (2022) C2

Soil transmitted helminth (STH) infections are among the most common human infections worldwide with over 1 billion people affected. Many estimates of STH infection are often based on school-aged children (SAC). This study produced predictive risk-maps of STH on a more finite scale, estimated the nu ... mber of people infected, and the amount of drug required for preventive chemotherapy (PC) in Ogun state, Nigeria. Georeferenced STH infection data obtained from a cross-sectional survey at 33 locations between July 2016 and November 2018, together with remotely-sensed environmental and socio-economic data were analyzed using Bayesian geostatistical modelling. Stepwise variable selection procedure was employed to select a parsimonious set of predictors to predict risk and spatial distribution of STH infections. The number of persons (pre-school ages children, SAC and adults) infected with STH were estimated, with the amount of tablets needed for preventive chemotherapy. An overall prevalence of 17.2% (95% CI 14.9, 19.5) was recorded for any STH infection. Ascaris lumbricoides infections was the most predominant, with an overall prevalence of 13.6% (95% CI 11.5, 15.7), while Hookworm and Trichuris trichiura had overall prevalence of 4.6% (95% CI 3.3, 5.9) and 1.7% (95% CI 0.9, 2.4), respectively. The model-based prevalence predictions ranged from 5.0 to 23.8% for Ascaris lumbricoides, from 2.0 to 14.5% for hookworms, and from 0.1 to 5.7% for Trichuris trichiura across the implementation units. The predictive maps revealed a spatial pattern of high risk in the central, western and on the border of Republic of Benin. The model identified soil pH, soil moisture and elevation as the main predictors of infection for A. lumbricoides, Hookworms and T. trichiura respectively. About 50% (10/20) of the implementation units require biannual rounds of mass drug administration. Approximately, a total of 1.1 million persons were infected and require 7.8 million doses. However, a sub-total of 375,374 SAC were estimated to be infected, requiring 2.7 million doses. Our predictive risk maps and estimated PC needs provide useful information for the elimination of STH, either for resource acquisition or identifying priority areas for delivery of interventions in Ogun State, Nigeria. more

ORS and Zinc tablets stops diarrhoea faster and protects

Global Health: Science and Practice (2016) CC2

A poster advertising oral rehydration salts (ORS) and zinc, part of the SHOPS mass media campaign in Ghana, was distributed widely to pharmacies and over‐the‐counter medicine sellers to improve caregivers’ and providers’ awareness of the new ... more

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Fascioliasis animal parasitic disease

Pan American Health Organization PAHO; World Health Organization WHO (2022) C_WHO

Fascioliasis is an animal parasitic disease (in cattle and sheep, but also pigs, donkeys, Llamas and alpacas that can be transmitted to humans. The infection is caught when aquatic or semi-aquatic plants with the larvae of the worm attached to their stem or leaves are ingested raw or poorly cooked. ... more

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Progress towards elimination of lymphatic filariasis in the Americas region

G. Fontes, da Rocha, E. M. M.; Carvalho Scholte, R. G.; et al. International Health (2020) C1

In South and Central America, lymphatic ﬁlariasis (LF) is caused by Wuchereria bancrofti, which is transmitted by Culex quinquefasciatus, the only vector species in this region. Of the seven countries considered endemic for LF in the Americas in the last decade, Costa Rica, Suriname and Trinidad a ... more