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This publication is an updated version of the Management of Tuberculosis and HIV Coinfection clinical protocol released in 2007 by the WHO Regional Office for Europe. It is intended for all health care workers involved in preventing, diagnosing, treating and caring for people living with TB and HIV ... more

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National Institute for Health and Clinical Excellence (2012)
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A Joint Position Statement of the Indian Society of Critical Care Medicine (ISCCM) and the Indian Association of Palliative Care (IAPC) Indian Journal of Critical Care Medicine September 2014 Vol 18 Issue 9
Sixth edition 2007
MMWR: Recommendations and Reports / Vol. 62 / No. 9 Morbidity and Mortality Weekly Report October 25, 2013
Ensuring Access to Simple, Safe and Effective First-Line Medicines for Tuberculosis. Accessed in November 2017.
Health and Human Rights Journal December 2016 / Volume 18 / Number 2 / Papers, 171-182
Research Emerging Infectious Diseases Vol. 12, No. 5, May 2006
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Bulletin of the World Health Organization, 2001, 79 (4)
Final report 2016
These are integrated National Guidelines 2013 for Prevention and Management of HIV, STIs & Other Blood Borne Infections in accordance with the last guidelines of the World Health Organization (WHO) published in June 2013 and adapted to the Rwandan national context. It thus responds to the need by th ... more
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Medicinal plants are globally valuable sources of herbal products, and they are disappearing at a high speed. This article reviews global trends, developments and prospects for the strategies and methodologies concerning the conservation and sustainable use of me ... more
International Journal of Drug Policy 24 (2013) e91-98
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Prepared as an outcome of ICMR Subcommittee on Breast Cancer |.This consensus document on management of breast cancers summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also inter ... more
Prepared as an outcome of ICMR Subcommittee on Colorectal Cancer | Coordinated by Division of Non Communicable Diseases | This Consensus Document on Management of Colorectal Cancer summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative ca ... more
Prepared as an outcome of ICMR Subcommittee on Gastric Cancer | This consensus document on Management of Gallbladder cancers summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also ... more
Prepared as an outcome of ICMR Subcommittee on Multiple Myeloma | This consensus document on management of multiple myeloma summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also i ... more
Prepared as an outcome of ICMR Subcommittee on Soft Tissue Sarcoma and Osteosarcoma | This consensus document on Management of Soft Tissue Sarcoma and Osteosarcoma summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular ... more
Prepared as an outcome of ICMR Subcommittee on Tongue Cancer | This Consensus Document on Management of Tongue Cancers summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also interw ... more
Schizophr Bull. 2014 Jan;40(1):192-213. doi: 10.1093/schbul/sbs150. Epub 2012 Dec 17.
20 February 2013 Update on 2004 Background Paper (Written by Saloni Tanna) Priority Medicines for Europe and the World "A Public Health Approach to Innovation"
Q4: For people with dementia with associated depression, do antidepressants when compared to placebo/comparator produce benefits/harm in the specified outcomes?

Role of Memantine

World Health Organization (2012) C_WHO
Q2: For people with dementia, does memantine, when compared to placebo/comparator, produce benefits/harm in the specified outcomes in non-specialist health settings?
November 3, 2009https://doi.org/10.1371/journal.pmed.1000176 PLoS Med 6(11): e1000176. https://doi.org/10.1371/journal.pmed.1000176
SCOPING QUESTION: For adults and children with medication-resistant convulsive epilepsy, which anti-epileptic medications produce benefits and/or harm in the specified outcomes when compared to a placebo or a comparator?
SCOPING QUESTION: In adults with established status epilepticus (i.e., seizures persisting after the first-line treatment with benzodiazepines [or benzodiazepines-resistant status epilepticus]), which anti-epileptic medications are associated with cessation of seizures and reduced adverse effects)? ... more

Management of epilepsy in women of child bearing age

World Health Organization (2012) C_WHO
Q11: 11a). In women with epilepsy, should antiepileptic therapy be prescribed as monotherapy or polytherapy to decrease the risk of fetal malformations? 11b). Does the use of folic acid preconceptually decrease the risk of foetal malformations in women with epilepsy? 11c). Do phenytoin, phenobarbi ... more

Epilepsy - WHO factsheet

World Health Organization (2019) C_WHO
7 February 2019
The Guide

Epilepsy - A manual for Medical and Clinical Officers in Africa

International League Against Epilepsy; World Health Organization; International Bureau for Epilepsy (2002) C_WHO

Epilepsy - Infosheets

World Health Organization (2019) C_WHO
Accessed: 10.03.2019

Module: Epilepsy

World Health Organization World Health Organization (2019) C_WHO
Accessed: 10.03.2019 mhGAP Training Manual for the mhGAP Intervention Guide for mental, neurological and substance use disorders in non-specialized health settings – version 2.0 (for field testing)
Position Statement Diabetes Care2018;42(Suppl. 1):S1–S194.
В этом дискуссионном документе излагаются факты, касающиеся передозировки опиоидов, мер, которые могут быть приняты в целях предупреждения и лечения (коррекции) п ... more
This study was designed to examine the knowledge, attitude and beliefs about causes, manifestations and treatment of mental illness among adults in a rural community in northern Nigeria.
Growing evidence indicates that large proportions of children around the world experience physical, sexual and emotional violence every year, with enormous implications for human rights, public health and economic and social development.1 Over the last five years, national governments and Together f ... more
Q6: In individuals with psychotic disorders (including schizophrenia) who require long term antipsychotic treatment, are anticholinergic medications more effective in preventing or reducing extrapyramidal side-effects and/or improving treatment adherence than placebo/treatment as usual?
Session outline •Introduction to epilepsy. •Assessment of epilepsy. •Management of epilepsy. •Follow-up of a person with epilepsy. •Review or materials and skills.
Version 1.0
Version 1.0
Manual for use in primary care. This manual explains the theoretical basis and evidence for the effectiveness of brief interventions and assists primary health care workers in conducting a simple brief intervention for clients whose substance use is putting them at risk.
The ASSIST package is developed to help the primary health professionals to detect and manage substance use and related problems in primary and general medical care settings. Download the ASSIST screening test version 3.0 and feedback card The ASSIST screening test version 3.0 is availa ... more

HIV care and support

UNAIDS (2016) C2
UNAIDS 2016, Reference HIV care and support taking into account the 2016 WHO consolidated guidelines
A case study from Bosnia and Herzegovina Eurasian Harm Reduction Network The case study was prepared by Samir Ibisevic, President of PROI between March and June 2016 and edited by Graham Shaw. EHRN is grateful to all who contributed to this document, especially: Dr. Serifa Godinjak, Chairperson ... more

WHO mission on ART optimization in Belarus March 30-31, April 1, 2016

M. Ristola; V. Rusovich; J. Lundgren; S. F. Jakobsen World Health Organization (Europe); WHO Collaborating Centre on HIV and Viral Hepatitis (2016) C2
April, 2016

Optimization of ART in Ukraine: general principles of ART optimization from a public health perspective

Professor J. Lundgren World Health Organization (Europe); Centre for Health & Infectious Disease Research (2016) C_WHO
Mission report April 2016

Legal environment Assessment for HIV in Ukraine

USAID (U.S. President’s Emergency Plan for AIDS Relief) (2017) C2
Rueda S, et al. BMJ Open 2016;6:e011453. doi:10.1136/bmjopen-2016-011453
PLOS ONE | https://doi.org/10.1371/journal.pone.0196239 April 23, 2018
В настоящем отчете (это уже четвертое его издание) анализируются препятствия и факторы, затрудняющие доступ к препаратам для лечения лекарственно-устойчивого туб ... more
Supplement Article www.jaids.com J Acquir Immune Defic Syndr  Volume 78, Supplement 1, August 15, 2018
Scientific Advice
HIV i-Base July 2018
Research Article Hindawi BioMed Research International Volume 2018, Article ID 9619684, 10 pages https://doi.org/10.1155/2018/9619684
Accessed: 03.03.2020
Tuberculosis treatment failure results in increased risk of morbidity, drug resistance, transmission and mortality. There are few data about tuberculosis treatment outcomes in Burkina Faso. The current study investigated the factors associated with tuberculosis treatment failure in the central east ... more
Nosocomial infections and antimicrobial resistance are two special health issues listed in Annex 1 of Commission Decision 2000/96/EC of 22 December 1999 on the communicable diseases to be progressively covered by the Community network under Decision No 2119/98/EC of the European Parliament and of th ... more
An essential participant in antimicrobial stewardship who has been unrecognized and underutilized is the“staff nurse.”Although the role of staff nurses has not formally been recognized in guidelines for implementing and operating antimicrobial stewardship programs (ASPs) or defined in the medica ... more
9 April 2020 WHO has published the guidance “Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected” This document is intended for clinicians taking care of hospitalized adult and paediatric patients with severe acute respiratory infection (SARI) whe ... more
This document updates the earlier version published in April 2020. In recent weeks, information on the potential use of chloroquine or hydroxychloroquine for the treatment of people with COVID-19 has been disseminated in academic journals and public media. Although there are now ongoing clinical tri ... more
This is an abridged version of the 2019 Standards containing the evidence-based recommendations most pertinent to primary care. The tables and figures have been renum-bered from the original document to match this version. The complete 2019 Standards of Care do ... more
Facilitator's Guide Refresher Training Module for Health Care Providers implementing the MISP Inter-agency Working Group on Reproductive Health in Crises Training Partnership
Sepsis remains a leading cause of mortality and morbidity, especially during the first five days of life and in low and middle-income countries (LMIC) [1]. Hospital infection also remains a major cause of mortality in children despite progress encountered in the last decades.
Anaesthesia Tutorial of the Week
As of 31 October 2020 This is the tenth edition of this summary of rapid systematic reviews, which includes the results of a rapid systematic review of currently available literature. More than 200 therapeutic options or their combinations are being investigated in more than 1,700 clinical trials. I ... more
This twelfth version of the WHO living guideline now contains 19 recommendations. This latest update provides updated recommendations for remdesivir, addresses the use of combination therapy with corticosteroids, interleukin-6 (IL-6) receptor blockers and Janus kinase (JAK) inhibitors in patients wi ... more
An Evidence-Based Treatment Guide for Clinicians