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The manual is written for clinicians working at the district hospital (first-level referral care) who diagnose and manage sick adolescents and adults in resource constrained settings. It aims to support clinical reasoning, and to provide an effective clinical approach and protocols for the managemen ... more
Gender-based violence, including rape is a problem throughout the world, occurring in every society, country and region. Refugees and internally displaced people are particularly at risk of this violation during every phase of an emergency situation. The systematic use of sexual violence as a method ... more
These consolidated guidelines on HIV testing services (HTS) bring together existing and new guidance on HTS across different settings and populations. The World Health Organization (WHO) first released consolidated ... more
J Hepatol (2017), http://dx.doi.org/10.1016/j.jhep.2017.03.021
This strategic framework marries formerly separate mandates for HIV and TB management in to one, comprehensive collaboration. It provides a structure for how to: strengthen the health care system to respond effectively to both epidemics, reduce the burden of HIV/AIDS in TB patients, and establish a ... more
Accessed November, 2017
Updated to Reflect the 2009 Medical Eligibility Criteria of the World Health Organization

Guidelines for Addressing HIV in Humanitarian Settings

UNAIDS; IASC (Inter-Agency Standing Committee) (2010) C2
UNAIDS/10.03E / JC1767E (English original, March 2010) ISBN 978 92 9 173849 6
Trainer Manual Introduction (Section 1-3)
These guidelines were developed as part of Kenya's fast-track plan to end AIDS among adolescents and young people. Based on research into adolescent and young key populations in Kenya and elsewhere, they outline a package of HIV prevention services, ... more

Act Toolkit 2.0 - Advocacy for community Treatment

B. Killingo; T. Taro; E. Whyle; et al. ITPC (International Treatment Preparedness Coalition) (2016) C2
Strengthening Community responses to HIv Treatment and Prevention
The Zambia Population Based HIV impact assessment of 2016, reported the prevalence of viral hepatitis in Zambia as ranging between 5.6% among adults aged 15 to 59% in the general population, and 7.1% among HIV infected individuals. It is estimated that the majority of persons with chronic hepatitis ... more

National Contraception Clinical Guidelines 2019

Department of Health National Department of Health South Africa (2019) CC
The Department of Health (DOH) has developed a National Integrated Sexual and Reproductive Health and Rights (SRHR) Policy.1 This policy addresses the many cross-cutting issues relating to SRH service provision, drawing together the principles, rights, and guidance for planning and implementation th ... more
Guidance for health workers
Guidelines for national programmes and other stakeholders, for annexes see http://www.who.int/tb/publications/2012/tb_hiv_policy_9789241503006/en/
The new WHO guidelines provide recommended steps for safe phlebotomy and reiterate accepted principles for drawing, collecting blood and transporting blood to laboratories/blood banks.
Evidence-to-Decision and Grade tables

Paediatric - HIV Care and Treatment

USAID; Pata; South to South Zoe life; et al. (2019) C2
Accessed: 08.10.2019
Review Drake AL et al. Journal of the International AIDS Society 2019, 22:e25271 http://onlinelibrary.wiley.com/doi/10.1002/jia2.25271/full | https://doi.org/10.1002/jia2.25271
Research Article PLOS ONE | https://doi.org/10.1371/journal.pone.0192791 February 15, 2018

Fast-tracking HIV treatment: Parliamentary action and policy options

P. Bayr; L. Davies; F. Ndugulile; et al. Inter-Parliamentary Union (For democracy, For everyone); UNAIDS (2015) C2
Supplement Article J Acquir Immune Defic Syndr  Volume 75, Supplement 2, June 1, 2017 www.jaids.com
Joint United Nations Programme on HIV/AIDS (UNAIDS).
These guidelines provide evidence-based guidance on the use of peripartum antiviral prophylaxis in HBsAg-positive pregnant women for the prevention of mother-to-child transmission of HBV.
This first edition of our national neonatal care clinical guidelines is an initiative that aims to ensure that all the neonates in the Kingdom of Eswatini are offered standard, best quality of care and the best possible start in life. The ... more
Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ... more
Patients with retreatment tuberculosis (TB) represent those who have been treated previously for onemonth ormorewith anti-TB drugs and who have been diagnosed once again with the disease.These patientsmainly include relapses, treatment after fai ... more
Guidelines HIV testing services July 2015
Interim policy guidance
A Training Curriculum for Multidisciplinary Healthcare Teams. This innovative training package aims to empower multidisciplinary health workers to have the confidence and skills to provide comprehensive, youth-friendly HIV services that support adolescents’ healthy development, psychosocial well b ... more
The curriculum, which complements the national pediatric ART training, was finalized in 2011 and was subsequently implemented nationally. The training curriculum includes a 15-module Trainer Manual, a Participant Manual, and accompanying PowerPoint slides.
This publication provides guidance to governments, civil society organizations (nongovernmental organizations and community-based organizations) and other partners implementing HIV prevention, care and treatment programs with key populations. This g ... more
Updated May 2017
This document is meant to respond to the questions:
■ What health interventions should the child receive and when should s/he receive it?
■ What health behaviours should a mother/caregiver practise (or not practise)?
Updated May 2017
This document is meant to respond to the questions:
■ What health interventions should be delivered during pregnancy, childbirth and the postnatal period?
■ What health behaviours should the women practise (or not practise) during these periods to care for ... more
PLOS ONE | https://doi.org/10.1371/journal.pone.0196239 April 23, 2018
Anema et al. AIDS Research and Therapy 2011, 8:13 http://www.aidsrestherapy.com/content/8/1/13
Research Article PLOS ONE | https://doi.org/10.1371/journal.pone.0189770 January 2, 2018
Journal of Tuberculosis Research, 2017, 5, 189-200 Background: In Benin, little is known about the influence of both gender and HIV-status on diagnostic patterns and treatment outcomes of Tuberculosis (TB) patients. Objective: To assess whether ... more
The Guidelines on promotive and preventive mental health interventions for adolescents - Helping Adolescents thrive (HAT), provide evidence-informed recommendations on psychosocial interventions to promote mental health, prevent mental disorders, an ... more

HIV Programme Review in Albania: Antiretroviral therapy and procurement and supply management

J. V. Lazarus; M. Gottfredsson; N. Tavagnutti World Health Organization (Europe); Centre for Health & Infectious Disease Research (2015) C_WHO
March 2015
BMJ,Dodd PJ, et al. Thorax 2017;72:559–575. doi:10.1136/thoraxjnl-2016-209421
AIDS Behav (2017) 21:S23–S33 DOI 10.1007/s10461-016-1670-9
Rutstein SE et al. Journal of the International AIDS Society 2017, 20:21579 http://www.jiasociety.org/index.php/jias/article/view/21579 | http://dx.doi.org/10.7448/IAS.20.1.21579
This 2011 update of Guidelines for the programmatic management of drug-resistant tuberculosis is intended as a tool for use by public health professionals working in response to the Sixty-second World Health Assembly’s resolution on prevention an ... more
Cancer, diabetes, heart disease and stroke, chronic respiratory disease
In the area of nutrition and HIV, children deserve special attention because of their additional needs to ensure growth and development and their dependency on adults for adequate care. It was therefore proposed to first develop guidelines for chil ... more
Available in: English, French, Chinese, Spanish, Russian, Arabic, Thai, Korean, Tajik, Vietnamese, Uzbek http://www.who.int/disabilities/cbr/guidelines/en/
Good practice examples from India
There is an urgent need for safer, simpler, more efficacious and accessible treatment regimens for all forms of TB. The development of Target Product Profiles for TB treatment regimens (referred to ... more
Interim policy guidance.
A review of available evidence (2016). 28-29 June 2016; Geneva, Switzerland The END TB strategy.
The toolkit is a collection of assessment tools and checklists that describe the key considerations to be taken into account when transitioning to Option B/B+. The toolkit provides a roadmap to support the planning and implementation of Option B/B+, and to help countries scale up more effective inte ... more

Barriers to Access: Medication-Assisted Treatment and Injection-Driven HIV Epidemics

Open Society Institute - Public Health Program; International Harm Reduction Development Program (IHRD) (2019) C2
Public Health Factsheet Accessed: 29.09.2019
Legislative and Policy analysis and recommendations for reform
PLOS ONE | https://doi.org/10.1371/journal.pone.0183180 October 9, 2017
Technical Report AIDS Medicines and diagnostics service September 2016
Topics in Antiviral Medicine 25 Issue 2 May/June 2017

HIV prevention, treatment and care in prisons and other closed settings: a comprehensive package of interventions

World Health Organization; UNODC (United Nations Office on Drugs and Crime); UNAIDS; et al. (2013) C_WHO
Policy Brief
To provide a foundation for the strategic policy and programme development needed to ensure the sustainable implementation of effective interventions for reducing the global burden of PPH
Practical guide intended for physicians, pharmacists, nurses and medical auxiliaries. This guide is not a dictionary of pharmacological agents. It is a practical manual intended for health professionals, physicians, pharmacists, nurses and health auxiliaries invoved in curative care and drug managem ... more
Supplement HIV testing services December 2016
The application of digital health technology is growing at a rapid rate in Africa, with the goals of improving the delivery of healthcare services and more effectively reaching out to remote and underserved communities. The lack of enabling guidelines ... more
HIV, viral hepatitis and STI epidemics, particularly among people who inject drugs and other key populations, continue to be fuelled by laws and policies criminalizing sex work; drug use or possession; diverse forms of gender expression and sexuality; stigma and discrimination; gender discrimination ... more
Clinical Infectious Diseases 1586 - 1594 • CID 2016:62 (15 June) • HIV/AIDS
Evaluation Report Evaluation Office
A Systematic Review and Meta-analysis Clinical Infectious Diseases® 2016;62(12):1586–94