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Rapid Communication: Molecular assays as initial tests for the diagnosis of tuberculosis and rifampicin resistance

World Health Organization WHO (2020) C_WHO

This Rapid Communication aims to inform national TB programmes and other stakeholders about the key implications of the latest evidence on the use of specific molecular assays as initial diagnostic tests of pulmonary and extrapulmonary TB and RR-TB, in adults and children.

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Standard Operating Procedures on Viral Load Monitoring for ICAP Clinical Staff and Health Care Workers: A Template Document for Country Adaptation

ICAP (2016) C1

Version 1.1 July 2016
The purpose of this document is to describe standard operating procedures for viral load monitoring, including the schedule for viral load testing when used for routine monitoring of children, adolescents and adults on ART; interpretation of results; patient management; an... more

Prevention of Allergy and Allergic Asthma

World Health Organization WHO; World Allergy Organization-IAACI (WAO) (2002) CC2

The prevalance of asthma an allergy, defined as immunologically mediated hypersensitivity, is increasing. It is estimated that over 20% of the world population suffers from IgE-mediated allergic disease, such as allergic asthma, allergic rhinitis and allergic conjunctivitis, atopic eczema/atopic der... more

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Schistosomiasis and soil-transmitted helminthiases: progress report, 2022

World Health Organization WHO (2023) C_WHO

Human schistosomiasis is caused mainly by 3 schistosome species: Schistosoma haematobium, S. mansoni and S. japonicum. S. guineensis, S. intercalatum and S. mekongi have a highly localized distribution in Central Africa and along the Mekong River in South-East Asia, respectively. Soil-transmitted h... more

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Singing to the Lions. A Guide to Overcoming Fear and Violence in Our Lives
recommended

Brakarsh, J.; L. Steinitz Catholic Relief Services CRS (2018) CC

Singing to the Lions is a free training package (facilitator’s guide, supplement and video) by CRS, that is designed to help children and youth lessen the impact of violence and abuse in their lives. The main component is a three-day workshop where participants learn skills that can help them tran... more

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National Manual for the Management of HIV-related Opportunistic Infections and Conditions

Ministry of Health, Kenya (2008) C2

A healthcare worker manual. 2nd edition The development of this National Manual for the Management of HIV-related Opportunistic Infections and Conditions for use by health care workers at the frontline of our fight against HIV/AIDS is intended to improve their understanding of the causes, preventio... more

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THE PREVALENCE OF POST-TRAUMATIC STRESS DISORDER AMONG SEXUALLY ABUSED CHILDREN AT KENYATTA NATIONAL HOSPITAL IN NAIROBI, KENYA

Ombok, C.A., Obondo, A., Kangethe, R. & Atwoli, L. East African Medical Journal (2013) C1

Background: Post-Traumatic Stress Disorder (PTSD) develops following some stressful events. There has been increasing recognition that children who have been exposed to traumatic events like child sexual abuse can develop post-traumatic stress disorder just like adults. Objective: To determine prev... more

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Estimating the population at risk with soil transmitted helminthiasis and annual drug requirements for preventive chemotherapy in Ogun State, Nigeria

Mogaji H.O., Johnson O.O. , Adigun A.B. et al Nature (2022) C2

Soil transmitted helminth (STH) infections are among the most common human infections worldwide with over 1 billion people affected. Many estimates of STH infection are often based on school-aged children (SAC). This study produced predictive risk-maps of STH on a more finite scale, estimated the nu... more

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SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020–March 2021

Kleynhans, J.; et al. (2021) C_CDC

EID Journal , Volume 27, no.12 , Dec. 2021. Early Release Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections may be underestimated because of limited access to testing. We measured SARS-CoV-2 seroprevalence in South Africa every 2 months during July 2020–March 2021 in randoml... more

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Rwanda: National Policy for Orphans and Other Vulnerable Children

Ministry of Local Government, Information and Social Affairs (Rwanda) (2003) C2

The following document outlines the principles, objectives and strategies of a national policy for the protection of orphans and other vulnerable children in Rwanda. The propositions constitute a first step towards a comprehensive framework, which will assist the Government and its partners to plan,... more

The Incidence of Adult-Onset Type 1 Diabetes: A Systematic Review From 32 Countries and Regions

Harding, J.L.; Wander, P.L.; Zhang, X.; et al. Diabete Care (2022) CC

The epidemiology of adult-onset type 1 diabetes (T1D) incidence is not well-characterized due to the historic focus on T1D as a childhood-onset disease.

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“We Have to Be Worried”. The Impact of Lead Contamination on Children’s Rights in Kabwe, Zambia

Human Rights Watch (2019) C1

Children in Kabwe are especially at risk because they are more likely to ingest lead dust when playing in the soil, their brains and bodies are still developing, and they absorb four to five times as much lead as adults. The consequences for children who are exposed to high levels of lead and are no... more

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Tanzania Malaria Indicator Survey (TMIS) Key Indicators 2017

Ministry of Health, Community Development, Gender, Elderly and Children; Ministry of Health; National Bureau of Statistics (NBS); Office of Chief Government Statistician (OCGS) (2018) C1

The primary objectives of the 2017 TMIS are to measure the level of ownership and use of mosquito nets; assess coverage of intermittent preventive treatment for pregnant women; identify treatment practices, including the use of specific antimalarial medications to treat malaria among c... more

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Ukraine received more than 700K doses of tetanus-diphtheria vaccine from UNICEF

UN Childrern's Fund Reliefweb OCHA Services (2021) C_UNICEF

To survive and thrive from early childhood through to adolescence and beyond, children need to be healthy. This enables them to access education so that every child in Ukraine, irrespective of background or circumstance, has an equal chance to fulfill their potential. To ensure children thrive and ... more

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Addressing childhood trauma in a developmental context

Gregorowski, C. & Seedat, S. Journal of Child and Adolescent Mental Health (2013) CC

Traditionally, understanding of the psychiatric and psychological effects of trauma have been developed from studies with adults and then applied to trauma-exposed children with some modifications. While this is an important step to understanding the sequelae of trauma in children and adolescents, t... more

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Guidance Note: IPC in Schools during AWD/Cholera Outbreaks

UN Children's Fund UNICEF; WASH Cluster (2023) C_UNICEF

WASH in schools during a cholera response is important due to the strong correlation between WASH and IPC. Not only can it impact the health and well-being of students and staff but also facilitate the potential spread of the disease via the congregation of children and adults from multiple househol... more

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Post-traumatic stress disorder: NICE guideline
recommended

National Institute for Health and Care Excellence (NICE) (2019) C1

NICE guideline | This guideline covers recognising, assessing and treating post-traumatic stress disorder (PTSD) in children, young people and adults. It aims to improve quality of life by reducing symptoms of PTSD such as anxiety, sleep problems and difficulties with concentration. Recommendations ... more

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Rabies Vaccine

Center for Disease Control and Prevention CDC (2014) CC

A regimen of four 1-mL doses of HDCV or PCEC vaccines should be administered intramuscularly to previously unvaccinated persons. The first dose of the four-dose course should be administered as soon as possible after exposure. Additional doses should be administered on days 3, 7, and 14 after the... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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The 2019 Global Multidimensional Poverty Index (MPI)

United Nations Development Programme (UNDP) and the Oxford Poverty and Human Development Initiative (OPHI) (2019) C1

This year’s MPI results show that more than two-thirds of the multidimensionally poor—886 millionpeople—live in middle-income countries. A further 440 million live in low-income countries. In both groups, data show, simple national averagescan hide enormous inequality inpatterns of povertywith... more

Singing to the Lions. A Guide to Overcoming Fear and Violence in Our Lives recommended

Post-traumatic stress disorder: NICE guideline recommended

Singing to the Lions. A Guide to Overcoming Fear and Violence in Our Lives
recommended

Post-traumatic stress disorder: NICE guideline
recommended