This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in
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South Sudan, and four hospitals in the Democratic Republic of the Congo between August 2005 and September 2009 to support the registration of pafuramidine for treatment of first stage HAT in collaboration with the United States Food and Drug Administration. Patients were treated with either 100 mg of pafuramidine orally twice a day for 10 days or 4 mg/kg pentamidine intramuscularly once daily for 7 days to assess the efficacy and safety of pafuramidine versus pentamidine. Pregnant and lactating women as well as adolescents were included.
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- Twenty-two joint integrated rapid response mechanism (IRRM) missions were conducted in 11 counties and reached 305,887 people including 65,432 children under 5 years of age.
- UNICEF’s Integrated Community Mobilization Network reached 345,2
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19 households (total population 2.1 million) advocating for child rights focused on child survival, birth notification, education and protection. Three million people have been reached with advocacy and life-saving messages through radio and community engagement activities, including activities focused on youth and faith leaders.
- On 27 June, discussions between President Salva Kiir and former First Vice President Riek Machar in Khartoum culminated in agreement to a permanent ceasefire and the opening of humanitarian corridors, effective 30 June.
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Following the declaration of the 9th Ebola Disease Outbreak (EVD) on 8 May 2018 by the Democratic Republic of Congo (DRC)
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Ministry of Health, the WHO has raised the alert for neighbouring countries of the Democratic Republic of the Congo (DRC) which share extensive borders, hosting DRC refugees and are used as corridors for DRC population movement. On 1 August 2018, just one week after the declaration of the end of the Ebola outbreak in Equator province, the 10th Ebola epidemic of the DRC was declared in the provinces of North Kivu and Ituri, which are among the most populated provinces in the DRC that also share borders with Uganda and Rwanda.
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In Kenya, 12.7 percent of sick Kenyans do not seek health care when they are ill with high cost of services being one
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of the major barriers that accounted for upto 21 percent of those who did not seek care in 2013. Further, 2.6 million Kenyans (6.2 percent) of households were at risk of impoverishment as a consequence of expenditure on health care depleting household savings and were at a risk of falling into poverty (Republic of Kenya 2015b).
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The Strategic plan aims to ensure alignment of preparedness and readiness actions in the nine countries focusing on eight technical areas: strengthening multisectoral coordination; surveillance for early detection; laboratory diagnostic capacity; po
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ints of entry; rapid response teams; risk communication, social mobilization and community engagement; case management and infection prevention and control (IPC) capacities; and, operations support and logistics. The purpose of the WHO Regional Strategic Plan is to ensure that the countries bordering the Democratic Republic of the Congo are prepared and ready to implement timely and effective risk mitigation, detection and response measures should there be any importation of EVD cases.
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Unstable settings present challenges for the effective provision of antiretroviral treatment (ART). In this paper, we summarize the experience and results of providing ART and implementing contingen
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cy plans during acute instability in the Central African Republic (CAR) and Yemen.
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2,202,059* South Sudanese refugees in the region as of 31 October 2019 (preand post-Dec 2013 caseload).
65,669* South Sudanese refugee’s arriv
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als so far in 2019, with 4,389 refugee arrivals in October 2019.
297,135 Refugees in South Sudan and 1.46 million IDPs with 12% inside six UNMISS Protection of Civilians sites.
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Covid19 - Standard Operating Procedures – UNHAS ROSS
This SOP defines WFP Aviation/UNHAS procedures to be followed when operating in areas affected by the current outbreak of the coronavirus disease (COVID-19). This SOP will be communicated to UN
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HAS staff, Operators, and user organisations.
According to World Health Organization (https://www.who.int/health-topics/coronavirus),
Coronaviruses (COVID-19) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome.
COVID19 – SOP v.1, 2 Apr 2020
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Morbidity and Mortality Weekly Report (MMWR) October 4, 2019 / 68(39);851–854
The cholera outbreak has affected 14 countries in the WHO African Region. The climate-induced natural disasters such as cyclone and flooding in the southern African region and drought in the Horn of Africa led to increase in cases
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of cholera in many of the affected countries. With the rainy season commencement in the west African region there is risk of more cholera outbreaks on the horizon. The trend across the region is being closely monitored and this highlights the need for Member States to enhance readiness, heighten surveillance and institute preventive and control measures in communities and around border crossings to prevent and mitigate cross border infection. Since 1 January 2022, a cumulative number of 213 443 cholera cases has been reported to the WHO Regional Office for Africa (AFRO), including 3 951 deaths with a case fatality ratio (CFR) of 1.9% as of 16 July 2023 (Table 1). Malawi accounts for 28% (58 941) of the total cases and 45% (1 766) of all deaths reported, and together with Cameroon, Democratic Republic of the Congo, Mozambique, and Nigeria contribute to 85% (181 300) of the overall caseload and 88% (3 464) of cumulative deaths. In Epidemiologic week 28, six countries Burundi, Cameroon, Ethiopia, Kenya, Malawi and Mozambique reported a total of 667 new cases.
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Please read and download the latest updates at the website
http://www.who.int/hac/crises/ssd/epi/en/
Armed conflict continues to tear apart communities across the world. From Boko Haram’s abducted ‘brides’ and Islamic State’s ‘Caliphate Cubs’, to the countless others exploited by armed groups in Democratic Republic
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of Congo, South Sudan and Afghanistan, many taking part in the world’s wars are still children.
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This document addresses preparedness as an important investment against natural and man-made disasters. Through good practices, it urges the humanitarian community, governments and regional bodies to use preparedness thinking to be aware of risks, t
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o reduce them and to plan ahead to combat them in order to respond more effectively and reduce the threat of hunger, disease, poverty and conflicts. It uses examples from Bangladesh, Bhutan, Bolivia, Colombia, Cook Islands, Ghana, Haiti, Indonesia, Kazakhstan, Korea, Democratic People’s Republic of Korea, Kyrgyzstan, Madagascar, Malawi, Mozambique, Namibia, Niger, Panama, Philippines, Samoa, Solomon Islands, South Africa, Sudan, Tanzania, Tonga, Turkmenistan, Uzbekistan, Vanuatu, Zambia and Zimbabwe
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