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The South African Heart Association's webpage provides comprehensive information about rheumatic heart disease (RHD). It addresses the causes, symptoms, and diagnostic methods of this condition. Additionally, it outlines prevention strategies and treatment options to raise awareness about RHD and pr...omote public health.
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The World Health Organization's Regional Office for Africa webpage on diabetes provides an overview of the disease's impact in the African Region. It highlights that diabetes is a serious, chronic, and costly condition, with projections estimating cases to rise to 23.9 million by 2030. The page outl...ines risk factors such as physical inactivity, overweight and obesity, tobacco use, and diets high in unhealthy fats and calories. It also discusses the three main types of diabetes: type 1, type 2, and gestational diabetes. Recent surveys indicate that up to 15% of adults aged 25 to 64 in the region have diabetes, with many unaware of their condition. The lack of access to proper treatment and medications, especially insulin, often leads to complications like neurological, vascular, or visual disorders, heart disease, stroke, lower limb amputation, and kidney failure.
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Diabetes Africa brings together healthcare professionals, entrepreneurs and decision-makers in Africa and its diaspora to make diabetes a thing of the past. We identify and promote innovation and innovators, and look for the next diabetes champions.
Background: Community health worker (CHW) programmes are a valuable component of primary care in resource-poor settings. The evidence supporting their effectiveness generally shows improvements in disease-specific outcomes relative to the absence of a CHW programme. In this study, we evaluated expan...ding an existing HIV and tuberculosis (TB) disease-specific CHW programme into a polyvalent, household-based model that subsequently included non-communicable diseases (NCDs), malnutrition and TB screening, as well as family planning and antenatal care (ANC).
Methods: We conducted a stepped-wedge cluster randomised controlled trial in Neno District, Malawi. Six clusters of approximately 20 000 residents were formed from the catchment areas of 11 healthcare facilities. The intervention roll-out was staggered every 3 months over 18 months, with CHWs receiving a 5-day foundational training for their new tasks and assigned 20–40 households for monthly (or more frequent) visits.
Findings: The intervention resulted in a decrease of approximately 20% in the rate of patients defaulting from chronic NCD care each month (−0.8 percentage points (pp) (95% credible interval: −2.5 to 0.5)) while maintaining the already low default rates for HIV patients (0.0 pp, 95% CI: −0.6 to 0.5). First trimester ANC attendance increased by approximately 30% (6.5pp (−0.3, 15.8)) and paediatric malnutrition case finding declined by 10% (−0.6 per 1000 (95% CI −2.5 to 0.8)). There were no changes in TB programme outcomes, potentially due to data challenges.
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Type 2 diabetes in adults
National Institute for Communicable Disease (NICE)
National Institute for Communicable Disease (NICE)
(2023)
CC2
The document provides the NICE Quality Standard for managing Type 2 diabetes in adults (QS209). It outlines evidence-based recommendations for preventing Type 2 diabetes, structured education, continuous glucose monitoring (CGM), medication such as SGLT2 inhibitors, and regular care processes to mon...itor complications. The guidelines emphasize individualized care, addressing health inequalities, and improving patient outcomes. They are intended to support healthcare professionals and services in delivering high-quality, equitable diabetes care.
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Type 2 diabetes in adults: management
National Institute for Communicable Disease (NICE)
National Institute for Communicable Disease (NICE)
(2022)
CC2
This guideline covers care and management for adults (aged 18 and over) with type 2 diabetes. It focuses on patient education, dietary advice, managing cardiovascular risk, managing blood glucose levels, and identifying and managing long-term complications.
The document "Management of Type 2 Diabetes Mellitus" provides comprehensive guidelines for the diagnosis, prevention, and treatment of type 2 diabetes in adults. It emphasizes the importance of individualized glycemic targets, lifestyle interventions like diet and exercise, and the use of medicatio...ns such as metformin, SGLT2 inhibitors, and GLP1 receptor agonists to manage blood sugar levels and reduce long-term complications. The document also discusses the screening and management of comorbidities such as hypertension, hyperlipidemia, and diabetic complications like retinopathy, neuropathy, and nephropathy. It highlights the role of diabetes self-management education and support in improving adherence to treatment and patient outcomes. The guidelines are evidence-based and aim to reduce morbidity and mortality associated with type 2 diabetes.
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The document "Pocketbook for Management of Diabetes in Childhood and Adolescence in Under-Resourced Countries" (2nd Edition) provides practical guidelines for managing diabetes in children and adolescents, particularly in resource-limited settings. It covers key topics like diagnosing and treating d...iabetes, managing diabetic ketoacidosis (DKA), insulin therapy, blood glucose monitoring, nutritional management, and dealing with complications. The pocketbook aims to support healthcare professionals in delivering effective diabetes care and improving outcomes for young patients in under-resourced areas.
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Although air pollution is well known to be harmful to the lung and airways, it can also damage most other organ systems of the body. It is estimated that about 500,000 lung cancer deaths and 1.6 million COPD deaths can be attributed to air pollution, but air pollution may also account for 19% of all... cardiovascular deaths and 21% of all stroke deaths. Air pollution has been linked to other malignancies, such as bladder cancer and childhood leukemia. Lung development in childhood is stymied with exposure to air pollutants, and poor lung development in children predicts lung impairment in adults. Air pollution is associated with reduced cognitive function and increased risk of dementia. Particulate matter in the air (particulate matter with an aerodynamic diameter < 2.5 μm) is associated with delayed psychomotor development and lower child intelligence. Studies link air pollution with diabetes mellitus prevalence, morbidity, and mortality. Pollution affects the immune system and is associated with allergic rhinitis, allergic sensitization, and autoimmunity. It is also associated with osteoporosis and bone fractures, conjunctivitis, dry eye disease, blepharitis, inflammatory bowel disease, increased intravascular coagulation, and decreased glomerular filtration rate. Atopic and urticarial skin disease, acne, and skin aging are linked to air pollution. Air pollution is controllable and, therefore, many of these adverse health effects can be prevented.
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The article "Air Pollution: The Emergence of a Major Global Health Risk Factor" discusses the significant health impacts of air pollution, a leading risk factor for global mortality. It highlights the adverse effects of fine particulate matter (PM2.5) and tropospheric ozone, linking them to cardiova...scular and respiratory diseases, cancer, and reduced life expectancy. While high-income countries have reduced air pollution levels, low- and middle-income countries face rising pollution, contributing to 4.9 million deaths in 2017. The article emphasizes the need for research to understand pollution’s health effects, identify key sources, and evaluate the effectiveness of interventions to improve air quality globally.
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The World Health Organization (WHO) highlights the significant health risks associated with household air pollution, primarily resulting from the use of inefficient and polluting fuels and technologies for cooking, heating, and lighting. In 2020, approximately 2.1 billion people—about one-third of... the global population—relied on open fires or inefficient stoves fueled by kerosene, biomass (such as wood, animal dung, and crop waste), and coal. This exposure led to an estimated 3.2 million deaths, including over 237,000 deaths of children under the age of five. The pollutants emitted from these sources contribute to a range of health issues, including respiratory infections, heart disease, stroke, chronic obstructive pulmonary disease, and lung cancer. The WHO emphasizes the urgent need for transitioning to cleaner fuels and technologies to mitigate these health risks.
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The World Health Organization (WHO) provides an overview of alcohol consumption and its global impact. Alcohol, containing ethanol, is a psychoactive and toxic substance that can lead to dependence. In 2019, alcohol consumption was responsible for approximately 2.6 million deaths worldwide, with 1.6... million resulting from noncommunicable diseases, 700,000 from injuries, and 300,000 from communicable diseases. Men accounted for the majority of these deaths, totaling 2 million, compared to 600,000 among women. Additionally, an estimated 400 million people aged 15 and older were living with alcohol use disorders in 2019.
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The IHME webpage discusses alcohol use as a significant global health risk, responsible for over 1.8 million deaths annually. It highlights age-related differences in alcohol's health impacts, with no benefits for individuals aged 15–39 and potential small benefits for those aged 40 and above unde...r certain conditions. The page emphasizes the need to consider factors like age, disease patterns, and individual health in assessing alcohol-related risks.
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The World Health Organization's Eastern Mediterranean Regional Office (WHO EMRO) highlights the significant health and social consequences of harmful alcohol use. Excessive alcohol consumption is linked to over 200 diseases and injuries, including liver cirrhosis, pancreatitis, various cancers, hemo...rrhagic stroke, and hypertension. Globally, it results in approximately 3.3 million deaths annually, surpassing fatalities from HIV/AIDS, violence, or tuberculosis. In the Eastern Mediterranean Region, while overall alcohol consumption is low, there is a concerning rise among adolescents and young adults, with patterns of heavy episodic drinking posing significant health risks. In response, the WHO has developed a global strategy to reduce the harmful use of alcohol, aiming to improve health and social outcomes by decreasing disease and death associated with alcohol consumption.
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OECD Data - Alcohol consumption
Organisation for Economic Co-operation and Development (OECD)
Organisation for Economic Co-operation and Development (OECD)
(2024)
CC
The OECD's "Alcohol Consumption" indicator measures the annual sales of pure alcohol in liters per person aged 15 and older. This metric helps assess long-term trends in alcohol consumption across countries. It's important to note that the methodology for converting alcoholic beverages to pure alcoh...ol may vary between nations. Additionally, official data typically do not account for tourist consumption or unrecorded alcohol intake, such as homemade or illegally produced alcohol. While this indicator provides insight into overall consumption patterns, it does not capture harmful drinking behaviors like heavy episodic drinking.
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The report provides an overview of alcohol consumption, related health harm, and policy responses in 30 European countries (EU Member States, Norway, and Switzerland). It highlights the high levels of alcohol consumption in the WHO European Region, which contribute to a significant disease burden co...mpared to other regions. The report covers trends in alcohol consumption and harm between 2010 and 2016, noting some progress in reducing alcohol-attributable mortality but stagnation in consumption reduction and heavy episodic drinking.
The assessment of alcohol policies shows variability in implementation across countries, particularly in areas like pricing and reducing the negative consequences of drinking. It emphasizes the need for stronger evidence-based policies, such as better regulation, taxation, and accessibility restrictions, to further reduce alcohol-related harm and achieve health-related Sustainable Development Goals.
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The article "Capacity-Building in Community-Based Drug Treatment Services" by Michael J. Cole focuses on the global challenges in providing adequate community-based drug treatment services. It highlights the gaps in availability, quality, and accessibility of evidence-based care. The article discuss...es the principles and strategies for capacity-building at three levels: individual, organizational, and service sector. It emphasizes using an empowerment model, engaging community stakeholders, and creating sustainable practices. The paper also addresses the need for systematic planning, assessment, and collaboration to strengthen drug treatment systems globally.
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The World Health Organization's fact sheet on opioid overdose highlights the significant global health issue posed by opioids, which include natural, semi-synthetic, and synthetic compounds used primarily for pain management. Misuse and unsupervised use can lead to dependence and severe health probl...ems. In 2019, approximately 600,000 deaths were attributed to drug use, with nearly 80% related to opioids; about 25% of these were due to overdose. An opioid overdose is characterized by pinpoint pupils, unconsciousness, and breathing difficulties. The fact sheet emphasizes the importance of increasing access to naloxone, an opioid antagonist that can rapidly reverse overdose effects, and advocates for training individuals likely to witness an overdose in its administration. It also underscores the need for comprehensive strategies, including preventive measures, treatment for opioid dependence, and policies to reduce opioid availability.
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The pamphlet "Alcohol and Depressants" explains the effects of depressants, including alcohol. Depressants slow brain activity by increasing the release of inhibitory neurotransmitters like GABA, leading to effects such as sedation, decreased anxiety, and reduced heart rate. Alcohol, a legal depress...ant, causes short-term effects like impaired judgment, vomiting, and blackouts, while long-term use can result in alcoholism, liver disease, strokes, and cancer. Alcohol withdrawal can be life-threatening, causing seizures and heart complications. The pamphlet emphasizes the importance of safe usage and provides resources for treatment and further information.
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The pamphlet "Marijuana" explains the effects and risks of cannabis use. It describes THC, the psychoactive compound in cannabis, which binds to cannabinoid receptors in the brain, causing effects like relaxation, altered perception, and euphoria. Short-term effects include red eyes, hunger, and anx...iety, while long-term effects may involve memory loss, lung problems, and slowed brain development, especially with early and frequent use. It highlights the potential for negative impacts on mental and physical health while noting there are no direct deaths solely from marijuana use. The pamphlet provides links to resources for further information and recovery options.
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