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Health beliefs and health seeking behavior towards lymphatic filariasis morbidity management and disability prevention services in Luangwa District, Zambia: Community and provider perspectives

Maritim, P., A. Silumbwe, J.M. Zulu, et al. (2021) C2

Lymphatic filariasis (LF) infection if untreated results in fluid accumulation in the limbs or breasts (lymphedema) or genitalia (hydrocele) that is painful and causes great discomfort. Morbidity management and disability prevention (MMDP) strategies such as surgery for hydrocele, treatment of acute... more

Research priorities for Chagas disease, human African trypanosomiasis and leishmaniasis

World Health Organization WHO (2012) C_WHO

This report provides a review and analysis of the research landscape for three diseases – Chagas disease, human African trypanosomiasis and leishmaniasis – that disproportionately afflict poor and remote populations with limited access to health services. It represents the work of the disease re... more

Chagas Clinical Research Platform Newsletter

Drugs for Neglected Diseases Initiative DNDi Latin America (2022) CC

To support its R&D activities on Chagas disease, DNDi launched the Chagas Clinical Research Platform (CCRP). The platform brings together partners, experts, and stakeholders to provide support for evaluation and development of new treatments for Chagas disease. The patient-centred platform aims to f... more

Guidelines for Prevention and Control of Chikungunya Fever - 2009

World Health Organization - Regional Office for South-East Asia (2009) CC

This guideline for the prevention and control of chikungunya fever (CF) is intended for use by all peripheral health workers in the Region and is based on the strategy outlined above. This document will focus mainly on preventing, predicting and detecting outbreaks, and after detection, investig... more

Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Haemorrhagic Fever -Revised and expanded edition

World Health Organization WHO Regional Office for South-East Asia WHO Regional Office for South-East Asia (2011) CC

Revised and expanded version of the Guidelines

Strengthening the collection, analysis and use of health workforce data and information: a handbook

World Health Organisation (WHO) (2023) C_WHO

Access to health workers who are fit for purpose, motivated and protected is a fundamental force of health service delivery and the achievement of universal health coverage and the health and health-related Sustainable Development Goals. Data and knowledge of the distribution, skill mix and future d... more

Urogenital Schistosomiasis among Schoolchildren and the Associated Risk Factors in Selected Rural Communities of Kwara State, Nigeria

Sundar, S.; Abdulkareem, B.; Habeeb, K. et al. (2018) CC

Urogenital schistosomiasis is a common neglected tropical disease in many rural communities in African countries, with patches of infection in the Eastern Mediterranean Region. Globally, an estimated 239 million people are currently infected, with burden estimated at more than 3.5 million disability... more

WFP Regional Drought Response Plan for the Horn of Africa (January – December 2023)

World Food Programme WFP (2023) CC

After five consecutive below-average rains, the humanitarian crisis in the Horn of Africa is expanding and deepening. Combined with insecurity and macroeconomic volatility, the impact of the drought on food and nutrition security has been devastating. Across Ethiopia, Kenya and Somalia, an estima... more

Clinical Presentation of T.b. rhodesiense Sleeping Sickness in Second Stage Patients from Tanzania and Uganda

Kuepfer, I.; Hhary, EP.; Mpairwe, A.; Edielu, A.; Burri, C.; Blum, JA. PLOS Neglected Tropical Diseases (2011) CC

A wide spectrum of disease severity has been described for Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense (T.b. rhodesiense), ranging from chronic disease patterns in southern countries of East Africa to an increase in virulence towards the north. However, only limited d... more

Melarsoprol Resistance in African Trypanosomiasis

Fairlamb, A.H.; Horn, D. Elsevier Ltd. (2018) CC

Arsenical monotherapies were previously very successful for treating human African trypanosomiasis (HAT). Melarsoprol resistance emerged as early as the 1970s and was widespread by the late 1990s. Melarsoprol resistance represents the only example of widespread drug resistance in HAT patients wher... more

Developing New Diagnostic Tests for Human African Trypanosomiasis - Current status and future plans

HAT & OND Team Foundation for innovative new diagnostics FIND (2013) C2

FIND and Standard Diagnostics (SD) have developed a lateral flow rapid diagnostic test (RDT) to screen for T.b. gambiense HAT that is cheap and easy to use. The tests are packed individually and are stable at 40°C for up to 25 months; they are performed on fresh blood obtained from a finger prick... more

iagnostic Gaps and Recommendations for Human African Trypanosomiasis: Assessment of User Needs, Use Cases, and the Diagnostic Landscape

PATH (2016) C2

In support of the London Declaration goals, PATH aims to catalyze engagement of the diagnostics industry and product development efforts. As part of this work, PATH conducted a diagnostic landscape analysis to identify gaps and evaluated current and nascent HAT diagnostics that may provide solutions... more

Knowledge, attitudes and practices about human African trypanosomiasis and their implications in designing intervention strategies for Yei county, South Sudan

Bukachi, SA.; Mumbo, AA.; Alak, ACD.; Sebit, W.; Rumunu, J. et al. PLOS Neclected Tropical Diseases (2018) CC

A clear understanding of the knowledge, attitudes and practices (KAP) of a particular community is necessary in order to improve control of human African trypanosomiasis (HAT).New screening and diagnostic tools and strategies were introduced into South Sudan, as part of integrated delivery of primar... more

Communicating with caregivers about the Human Papillomavirus vaccination

World Health Organisation (WHO) (2023) C_WHO

This training module is designed to equip health workers (HWs) with knowledge, skills, confidence and resources to help them in their role to recommend the Human Papillomavirus (HPV) vaccine.

Responding to child maltreatment: a clinical handbook for health professionals

World Health Organisation (WHO) (2022) C_WHO

This handbook is intended primarily for front-line health care providers who are likely to see children (among other clients) in their day-to-day practice. These may include general practitioners, nurses, midwives, gynaecologists, paediatricians, mental health professionals, first responders and st... more

Monitoring the elimination of human African trypanosomiasis at continental and country level: Update to 2018

Franco, JR.; Cecchi, G.; Priotto, G.; Paone, M.; Diarra, A. et al. (2020) CC

Over the past twenty years, huge efforts made by a broad coalition of stakeholders curbed the last epidemic and brought the disease to the brink of elimination. In this paper, the latest figures on disease occurrence, geographical distribution and control activities are presented. Strong evidence in... more

Trypanosomiase humaine africaine : lutte et surveillance

World Health Organization WHO (2014) C_WHO

Un comité OMS d’experts sur la trypanosomiase humaine africaine (THA) : lutte et surveillance, s’est réuni à Genève (Suisse), du 22 au 26 avril 2013. Le Dr H. Nakatani, sous-directeur général pour le VIH/SIDA, la tuberculose, le paludisme et les maladies tropicales négligées, a ouvert la... more

Trends in maternal mortality 2000 to 2020: estimates by WHO, UNICEF, UNFPA, World Bank Group and UNDESA/Population Division

World Health Organisation (WHO) (2023) C_WHO

Every day in 2020, approximately 800 women died from preventable causes related to pregnancy and childbirth - meaning that a woman dies around every two minutes. Sustainable Development Goal (SDG) target 3.1 is to reduce maternal mortality to less than 70 maternal deaths per 100 000 live births by ... more

Leptospirosis in sugarcane plantation and fishing communities in Kagera northwestern Tanzania

Mgode, G.; Japhary, M.; Mhamphi, G. et al. PLoS Neglected Tropical diseases (2019) CC

Leptospirosis is a bacterial zoonotic disease of worldwide importance, though relatively neglected in many African countries including sub Saharan Africa that is among areas with high burden of this disease. The disease is often mistaken for other febrile illnesses such as dengue, malaria, rickettsi... more

Global Morbidity and Mortality of Leptospirosis: A Systematic Review

Costa, F.; Hagan, J.; Calcagno, J. PLoS Neglected Tropical diseases (2015) CC

Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis is a life-threatening disease and recognized as an important cause of pulmonary haemorrhage syndrom... more