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MSF الإرشادات السريرية. دليل التشخيص والعلاج
recommended

Médecins sans Frontières (MSF) (2022) C2
Clinical Guidelines. Diagnosis and Treatment Manual.
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Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions

Phillips, O.; J. Robert, K. Mohamed Abass et al. The Lancet Journal (2020) CC
The Lancet olume 395, ISSUE 10232, P1259-1267, April 18, 2020. Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia. Standard antimicrobial treatment with oral rifa... more
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Buruli ulcer: cured by 8 weeks of oral antibiotics?

Johnson, P.D.R. The Lancet Journal (2020) C1
Phillips and colleagues have shown that rifampicin combined with clarithromycin is non-inferior to RS8, and is safer. This much anticipated trial provides us with a high degree of confidence that an 8-week course of oral rifampicin and clarithromycin should now be the cornerstone of the treatment of... more
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The Chagas disease study landscape

Maguire, B.; Dahal, P.; Rashan, S. et al. PLoS Neglected Tropical Diseases (2021) CC
A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data platform. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations s... more
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Human African Trypanosomiasis (HAT) - Sleeping Sickness

Drugs for Neglected Diseases initiative DNDi (2008) C2
At the forefront of DNDi’s efforts to develop new treatments is the need to understand the realities and treatment needs of patients and health care staff in the field. The ultimate goal for human African trypanosomiasis (HAT) is a truly simplified treatment which can be orally administered, impl... more
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Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership.

Bernhard, S.; Kaiser, M.; Burri, C.; Mäser, P. Diseases (2022) CC
After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discovery for HAT with special emphasis on the discovery, pre-clinical development, and operational challenge... more
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Tsetse Control and Gambian Sleeping Sickness; Implications for Control Strategy

Tirados, I.; Esterhuizen, J.; Kovacic, V.; Mangwiro, TNC.; Vale, GA et al. PLOS Neglected Tropical Diseases (2015) CC
Sleeping sickness is controlled by case detection and treatment but this often only reaches less than 75% of the population. Vector control is capable of completely interrupting HAT transmission but is not used because of expense. We conducted a full scale field trial of a refined vector control tec... more
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Mindfulness meditation improves emotion regulation and reduces drug abuse

Tang, Y.Y.; Tang, R.; Posner, M.I. Drug and Alcohol Dependence (2016) CC
Background The core clinical symptoms of addiction include an enhanced incentive for drug taking (craving), impaired self-control (impulsivity and compulsivity), emotional dysregulation (negative mood) and increased stress reactivity. Symptoms related to impaired self-control involve reduced activi... more
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Ready to Use Therapeutic Food (RUFT) and the WHO Essential Medicines List

CMAM Forum (2018) CC
Severe Acute Malnutrition (SAM) is one of the greatest child survival challenges in the world today and reportedly affects more than 16.2 million children each year1. High impact, proven treatment interventions exist yet sadly approximately only 3.2 million children with SAM have access to treatme... more
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Health and Quality of Life Outcomes

Van der Molen, T.; Willemse, B.; Schokker, S.; et al. Health and Quality of Life Outcomes (2003) CC2
The new Global Obstructive Lung Disease (GOLD) guidelines advice to focus treatment in Chronic Obstructive Pulmonary Disease (COPD) on improvement of functional state, prevention of disease progression and minimization of symptoms. So far no validated questionnaires are available to measure symptom ... more
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Malawi - HIV Country Profile 2024

World Health Organization WHO (2024) C_WHO
Demographic and socioeconomic data Progress towards HIV testing and treatment cascade targets by 2025 (2023) Health sector cascade (2023) Estimated number of people newly infected with HIV
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South Sudan: Urgent action needed to address growing cholera outbreak- 13 November 2024

Medecins sans Frontieres (2024) C2
Médecins Sans Frontières (MSF) has set up a 20-bed cholera treatment unit (CTU) at the Renk Civil Hospital in South Sudan, in response to a cholera outbreak declared by the Ministry of Health (MoH) on 28 October. We call on all organisations in Upper Nile state to help prevent the spread of the di... more
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Standards and recommendations for burns care in mass casualty incidents

World Health Organization WHO (2024) C_WHO
Caring for burns patients from the incident scene to definitive treatment can be a complex, resource-consuming process with the potential to overwhelm health system capacity.This document provides practical guidance for building capacity and capability for burns care from clinical, human resources a... more
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Guidelines for essential trauma care
recommended

Mock, C et al World Health Organization (WHO) (2004) C_WHO
The Guidelines for essential trauma care seek to set achievable standards for trauma treatment services which could realistically be made available to almost every injured person in the world. They then seek to define the resources that would be necessary to assure such care. These include human res... more
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Ebola virus disease (EVD) – Key questions and answers concerning health care waste

World Health Organization (2021) C_WHO
Update September 2021. Safe management of health care waste practices play an essential role in protecting human health during all disease outbreaks, including during Ebola Virus Disease (EVD) outbreaks. This question and answer document provides practical, evidence-based recommendations on minimum... more
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Zika virus (English)
recommended

Hesperian Foundation (2016) C1
Fact sheet on Zika virus containing recommendations for pregnant women and information for the treatment, prevention and control of the disease. This factsheet is also available in Spanish, Portuguese and French!
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Viris Zika (Haitian Kreyol)

Hesperian Foundation (2016) C1
Fact sheet on Zika virus containing recommendations for pregnant women and information for the treatment, prevention and control of the disease. This factsheet is also available in English, Spanish, Portuguese and French!
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Guidance on tuberculosis control in vulnerable and hard-to-reach populations

Andreas Sandgren, Marieke J. van der Werf, Netta Beer et al. (2016) CC
This guidance provides an overview of interventions to improve early diagnosis of TB and treatment completion in these populations, as well as factors to consider when developing programmes for health communication, awareness and education, and programme monitoring and evaluation
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Nigeria: The National Strategic Plan for Tuberculosis Control 2015-2020

National Tubercolis and Leprosy Control Programme, Federal Ministry of Health, Nigeria (2015) C1
Towards Universal Access to Prevention, Diagnosis and Treatment
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Training Manual on Mental Health and Substance Abuse for Nurses and Paramedics

WHOSEARO (2015) C_WHO
Mental disorders are important public health concern in Bangladesh with a substantial treatment gap due to shortage of resources and trained relevant professionals, such as psychiatrists, psychologists, social psychologists, psychiatric nurses and occupational therapists. This manual is developed i... more