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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Beyond diagnosis and treatment The social protection landscape for people affected by TB in the WHO South-East Asia Region, 2024

World Health Organization WHO (2024) C_WHO

The social protection landscape for people affected by TB in the WHO South-East Asia Region

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ORAL REHYDRATION SALTS Production of the new ORS

World Health Organization; UNICEF WHO (2006) C_WHO

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Survivors and heroines: Women in the crisis in Burkina Faso

Oxfam; reliefweb (2020) C2

Over 1 million women in Burkina Faso caught between conflict and COVID-19 More than a million women and girls in Burkina Faso are facing increased sexual violence, hunger and water shortage as a result of the coronavirus pandemic on top of the existing conflict, said Oxfam today. In its report “... more

COVID-19: Water, sanitation and hygiene in schools - A safe return to schools for refugee children and youth

UN High Commissioner for Refugees UNHCR (2020) C1

This document presents the results of a survey assessing the WASH readiness of schools in UNHCR-supported refugee camps and refugee settlements. UNHCR and partners are using the results to improve water, sanitation and hygiene (WASH) COVID-19 mitigation measures in schools and design targeted improv... more

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Rapid communication on the systematic screening for tuberculosis

World Health Organization WHO (2020) C_WHO

External Link

UNICEF, WHO, IFRC and MSF announce the establishment of a global Ebola vaccine stockpile

World Health Organization WHO; et al. (2021) C_WHO

12 January 2021

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Ukraine: Civilian casualties as of 24:00 30 October 2022

UN Office of the High Commissioner for Human Rights (OHCHR) (2022) C2

ate: 31 October 2022 From 24 February 2022, when the Russian Federation’s armed attack against Ukraine started, to 30 October 2022, the Office of the UN High Commissioner for Human Rights (OHCHR) recorded 16,295 civilian casualties in the country: 6,430 killed and 9,865 injured. This included: -... more

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Global Fund Board discusses the lessons learned from the Seventh Replenishment and the action plan for the Eighth Replenishment

Independent Observer of Global Fund Aidspan (2023) CC

The Global Fund’s Board meeting on 14-16 November 2023 was its 50th; and among the many issues for information was on resource mobilization. The Board document provided an update on the status of the conversion of pledges and the signing of donor agreements. In addition, it presented the results... more

Green Nutrition

Camp, O.; Remans, R.; Colston, J. Global Alliance for Improved Nutrition gain (GAIN) (2023) CC

The document emphasizes integrating environmental considerations into nutrition programs. It introduces a screening tool piloted across ten projects to identify environmental risks and opportunities, fostering sustainable practices in food systems. The tool promotes collaboration, co-learning, and a... more

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Malaria Control in Humanitarian Emergencies. An Inter-Agency Field Handbook
recommended

Jose Nkuni, Natasha Howard, Abraham Mnzava et al. World Health Organization (2013) C_WHO

2nd edition. The interagency field handbook on malaria control was developed to set out effective malaria control responses in humanitarian emergencies, particularly during the acute phase when reliance on international humanitarian assistance is greatest. This second edition represents a thorough u... more

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Refugee Health
recommended

Médecins sans Frontières (1997) C3

An approach to emergency situations. Relief workers face rapidly changing and complex environments, new disease patterns, enormous humanitarian needs and relatively limited resources. The authors of this book use their experience in the area to produce an operational manual of the issues involved in... more

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View PDF (2007)

Staying alive: safety and security guidelines for humanitarian volunteers in conflict areas

David Lloyd Roberts International Comitee of the Red Cross (ICRC) (2005) C1

With its expert practical advice on security in situations of armed conflict, this updated set of guidelines will prove invaluable to humanitarian personnel working at the operational level. Following on from the success of the first edition, published in 1999, it addresses new and developing threat... more

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Essential Guide to Humanitarian Good Practice, 5th ed.
recommended

All in Diary (AID) (2016) C2

A practical tool for field based humanitarian workers. It provides up-to-date, clear and succint guidance on topics accross the humanitarian sector including references to current, relevant resources and practical tools.

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Real-time Evaluations of Humanitarian Action

John Cosgrave, Ben Ramalingam and Tony Beck ALNAP; Overseas Development Institute (2009) CC

An ALNAP Guide. Pilot Version. This pilot guide is intended to help evaluation managers to commission and oversee, and team leaders to conduct, RTEs of humanitarian operational responses. Drawing on a synthesis of existing good practices, it sets out a flexible approach that can be adapted to a var... more

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An Introduction to Evaluation of Humanitarian Action. Course Manual

Margie Buchanan-Smith and John Telford Channel Research; ALNAP (2006)

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Basic Epidemiology

Bonita, R.; R.Beaglehole, and T. Kjellström World Health Organization WHO (2006) C_WHO

2nd edition

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Minimum Standards in Shelter, Settlement and Non-Food Items
recommended

The Sphere Project (2016) C1

Links to the Humanitarian Charter and international law

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View PDF (2014)

Transitional Settlement - Displaced Populations

Tom Corsellis and Antonella Vitale University of Cambridge shelterproject; Oxfam (2005)

For the estimated 20 million refugees and 25 million internally displaced people worldwide, well-planned settlements can help to maximise their protection and security, and support them to minimise the spread of disease, manage natural resources sustainably, and maintain good relations with their ho... more