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Clinical Spectrum of Schistosomiasis

Carbonell, C.; Rodríguz-Alonso, B.; López-Bernús, A.; et al. MDPI Journal of Clinical Medicine (2021) CC

Schistosomiasis is a helminthic infection and one of the neglected tropical diseases (NTDs). It is caused by blood flukes of the genus Schistosoma. It is an important public health problem, particularly in poverty-stricken areas, especially those within the tropics and subtropics. It is estimated th... more

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Melarsoprol Resistance in African Trypanosomiasis

Fairlamb, A.H.; Horn, D. Elsevier Ltd. (2018) CC

Arsenical monotherapies were previously very successful for treating human African trypanosomiasis (HAT). Melarsoprol resistance emerged as early as the 1970s and was widespread by the late 1990s. Melarsoprol resistance represents the only example of widespread drug resistance in HAT patients wher... more

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iagnostic Gaps and Recommendations for Human African Trypanosomiasis: Assessment of User Needs, Use Cases, and the Diagnostic Landscape

PATH (2016) C2

In support of the London Declaration goals, PATH aims to catalyze engagement of the diagnostics industry and product development efforts. As part of this work, PATH conducted a diagnostic landscape analysis to identify gaps and evaluated current and nascent HAT diagnostics that may provide solutions... more

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Target product profile for a test for rhodesiense human African trypanosomiasis diagnosis usable in peripheral health facilities

World Health Organization WHO (2021) C_WHO

The development of this target product profile (TPP) was led by the WHO Department of Control of Ne- glected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was... more

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Knowledge, attitudes and practices about human African trypanosomiasis and their implications in designing intervention strategies for Yei county, South Sudan

Bukachi, SA.; Mumbo, AA.; Alak, ACD.; Sebit, W.; Rumunu, J. et al. PLOS Neclected Tropical Diseases (2018) CC

A clear understanding of the knowledge, attitudes and practices (KAP) of a particular community is necessary in order to improve control of human African trypanosomiasis (HAT).New screening and diagnostic tools and strategies were introduced into South Sudan, as part of integrated delivery of primar... more

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New hope for leishmaniasis

Drugs for Neglected Diseases initiative DNDi (2022) CC

Leishmaniasis is a climate-sensitive disease. Changes in temperature, rainfall, and humidity can have strong impacts on the sandfly vector, altering their distribution and influencing their survival and population sizes. Increased temperatures shorten vector development time, reduce Leishmania para... more

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Ethiopia - National Cholera Control Operational Plan 2022/23

Government of Ethiopia (2023) CC

Cholera is a diarrheal disease caused by the bacterium Vibrio cholera. The infection primarily spreads through contaminated water and food. Symptoms include the onset of acute diarrhea and/or vomiting, muscle cramps, and body weakness. If untreated, the infection can result in rapid dehydration and ... more

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Report of the fourth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination: virtual meeting, 1–3 June 2021

World Health Organization WHO (2021) C_WHO

Since 2000, concerted efforts by national programmes, supported by public–private partnerships, nongovernmental organizations, donors and academia under the auspices and coordination of the World Health Organization (WHO), have produced important achievements in the control of human African trypan... more

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Trypanosomiase humaine africaine : lutte et surveillance

World Health Organization WHO (2014) C_WHO

Un comité OMS d’experts sur la trypanosomiase humaine africaine (THA) : lutte et surveillance, s’est réuni à Genève (Suisse), du 22 au 26 avril 2013. Le Dr H. Nakatani, sous-directeur général pour le VIH/SIDA, la tuberculose, le paludisme et les maladies tropicales négligées, a ouvert la... more

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Gambiense human African trypanosomiasis: the bumpy road to elimination

Hasker E, Hope A, Bottieau E. Wolters Kluwer Health, Inc. (2022) C2

Gambiense human African trypanosomiasis is a deadly infectious disease affecting West and Central Africa, South Sudan and Uganda, and transmitted between humans by tsetse flies. The disease has caused several major epidemics, the latest one in the 1990s. Thanks to recent innovations such as rapid di... more

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Diagnosis and Clinical Management of Chagas Disease: An Increasing Challenge in Non-Endemic Areas

Suárez, C., Nolder, D., García-Mingo, A. et al. Research and reports in tropical medicine (2022) CC

Research and Reports in Tropical Medicine 2022:13 25–40. Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central, South America, Mexico and the South of the United States. It is an important cause of early mortality and morbidity, and it is associated with po... more

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Earthquake response in Türkiye and Whole of Syria
recommended

World Health Organisation (WHO) (2023) C_WHO

A 7.7 magnitude earthquake struck at 04:17 local time on 6 February 2023, with its epicentre located in Pazarcık district in Kahramanmaraş province, Türkiye. Over 1200 aftershocks have since been reported. These are Türkiye’ s most powerful earthquakes since 1939

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SYRIAN ARAB REPUBLIC response to earthquake: Situation report #3

World Health Organisation (WHO) (2023) C_WHO

In the early morning of 6 February 2023, a magnitude 7.8 earthquake struck southern Türkiye near the northern border of Syria. The earthquake was followed 11 minutes later by a magnitude 6.7 aftershock. Many aftershocks continue to be felt across the region. Whilst the impact is still being ass... more

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SYRIAN ARAB REPUBLIC response to earthquake: Situation report #2

World Health Organisation (WHO) (2023) C_WHO

In the early morning of 6 February 2023, a magnitude 7.8 earthquake occurred in southern Türkiye near the northern border of Syria. The earthquake was followed 11 minutes later by a magnitude 6.7 aftershock. Many aftershocks are still being felt across the region. Whilst the impact is still bei... more

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SYRIAN ARAB REPUBLIC response to earthquake: Situation report #1

World Health Organisation (WHO) (2023) C_WHO

TUATION UPDATE In the early morning of 6 February 2023, a magnitude 7.8 earthquake occurred in southern Türkiye near the northern border of Syria. The earthquake was followed 11 minutes later by a magnitude 6.7 aftershock. Many aftershocks are still being felt across the region. Whilst the imp... more

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Surveillance, prevention and control of leishmaniases in the European Union and its neighbouring countries

European Centre for disease prevention and control (ECDC) European Centre for disease prevention and control (ECDC) (2022) C_CDC

This technical report presents the epidemiology of human and animal leishmaniases in the EU and its neighbouring countries and concludes that the disease remains widespread and underreported in many countries of southern Europe, northern Africa, and the Middle East and that there is a need to improv... more

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Progress Toward Global Eradication of Dracunculiasis

Hopkins, D.; Weiss, A.; Roy, S. et al. Morbidity and Mortality Weekly Report MMWR; National Libary of Medicine (2020) CC

Dracunculiasis (Guinea worm disease), caused by the parasite Dracunculus medinensis, is traditionally acquired by drinking water containing copepods (water fleas) infected with D. medinensis larvae, but in recent years also appears increasingly to be transmitted by eating fish or other aquatic anima... more

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Eradication of yaws: a guide for programme managers, a disfiguring non-venereal disease

World Health Organization WHO (2018) C_WHO

Yaws is a disfiguring non-venereal disease caused by infection with the spirochaete. Treponema pallidum subspecies pertenue which is closely related to the causative agent of syphilis and those of the other endemic treponematoses, bejel and pinta. The disease is endemic in certain areas of the World... more

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A clinical case definition for post Covid-19 condition in children and adolescents by expert consensus

World Health Organisation (WHO) (2023) C_WHO

Background: The World Health Organization (WHO) published a clinical case definition of post COVID-19 condition, by a Delphi consensus, on 6 October 2021. That process concluded that a separate definition may be applicable for children. It is important to understand the frequency, characteristics ... more

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Conceptual and Operational Framework of Onchocerciasis Elimination with Ivermectin Treatment

World Health Organization WHO; African Programme for Onchocerciasis Control APOC (2010) C_WHO

Onchocerciasis used to be an important public health problem in Africa, with over 37 million people infected and millions suffering from debilitating skin disease, terrible itching, impaired vision and blindness. But the epidemiological situation has improved dramatically over the last two decades.... more

Earthquake response in Türkiye and Whole of Syria recommended

Earthquake response in Türkiye and Whole of Syria
recommended