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The guidelines reiterate that the general principles of ethics for biomedical research involving human participants shall also be applicable. In addition, the guidelines specify unique provisions for stem cells, because of their inherent property for unlimited proliferation, differentiation to cells
...
of the germ layers, oncogenic potential, unrecognised toxicities and possible involvement in pre-implantation stages of human development. The guideline therefore focuses on: 1. Monitoring mechanism and regulatory pathway for basic, clinical research and product development based on categories of research and level of manipulation. 2. Procurement of gametes, embryos and somatic cells for derivation and propagation of any stem cell lines, their banking and distribution. 3. Other important areas like international collaboration, exchange of cell/lines and education for stakeholders and advertisement.
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How the Greek reception system is failing to protect the most vulnerable people seeking asylum.
Greece and its EU partners are failing pregnant women, unaccompanied children, victims of torture or sexual violence and other vulnerable people who seek protection in Europe. These people are being put
...
at risk by flawed processes and chronic understaffing in EU ‘hotspot’ camps on the Greek islands. They do not receive adequate support from the authorities that are legally responsible for protecting them and are being abandoned in overcrowded camps in squalid conditions. Many people live in unheated tents and do not have sufficient access to washing facilities and toilets, and winter is only making their situation worse
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Post-Traumatic Stress Disorder (PTSD) in children and adolescents occurs when a child is exposed to one or more events that are unexpected, uncontrollable, life-threatening, and likely to cause serious harm or injury to himself/herself or someone significantly important to the child. In response, th
...
e child experiences fear, hopelessness, or horror and responds with a characteristic set of physiological and psychological reactions, which perpetuates the overwhelming and confusing feelings. Symptoms are characterized into three groups: persistent, intrusive re-experiencing of traumatic recollections; avoidance of reminders/numbing; and increased arousal.
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Accessed January 22, 2019.
This updated version include important research that has added to our knowledge about effective treatments for
child and adolescent depression. Its goal is to help parents and families make informed decisions about getting the best care for a child with depression. For
...
easy use, it is presented in Frequently Asked Questions (FAQ) format.
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PLoS Med 10(1): e1001366. https://doi.org/10.1371/journal.pmed.1001366
Published: January 8, 2013
Gurejeet al. BMC Health Services Research (2015) 15:242
DOI 10.1186/s12913-015-0911-3
Glob Ment Health (Camb). 2015; 2: e12. Published online 2015 Jul 14. doi: 10.1017/gmh.2015.10
Low and middle income countries (LMICs) are facing an increase of the impact of mental health problems while confronted with limited resources and limited access to mental health care, known as the ‘me
...
ntal health gap’. One strategy to reduce the mental health gap would be to utilize the internet to provide more widely-distributed and low cost mental health care. We undertook this systematic review to investigate the effectiveness and efficacy of online interventions in LMICs.
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mhGAP Training of Health-care Providers Training manual and Supporting material.
Int J Ment Health Syst. 2013 Jan 9;7(1):2. doi: 10.1186/1752-4458-7-2.
Q5.SCOPING QUESTION: In individuals with psychotic disorders (including schizophrenia) who require long-term antipsychotic treatment, what is the safety and role of depot antipsychotic medication?
1. What do we mean by ‘psychosocial support (PSS)? | 2. What are the basic principles of psychosocial support for UNICEF? | 3. In what types of situations does UNICEF address psychosocial support? | 4. Are there certain psychosocial interventions in which UNICEF should not normally seek to inves
...
t? | 5. Are there any types of interventions we should discourage? | 6. Should UNICEF support one-to-one counselling? In what situations might this be appropriate? | 7. When should children be referred for professional mental health support? | 8. Should we avoid using the term “traumatised” when referring to children? | 9. How do we assess the type or response needed a) for quick, short term action? b) for medium-long term interventions? | 10. How can caregivers and professionals who have themselves experienced the same crises or exposures provide psychosocial support to children? | 11. What materials and tools are recommended to support and monitor PSS interventions? Where can these be obtained?
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Our goal at Voices for Georgia’s Children is to help decision-makers craft and implement policies that ensure Georgia’s children grow up to be healthy, educated and productive citizens. To that end, we have developed a comprehensive policy agenda focused on early childhood, child health and disc
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onnected youth, which, if followed, can effectively prevent and offset some of the damaging experiences faced by our children. Many of our recommendations are aligned with those included in this policy brief.
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Information booklet on Post Traumatic Stress Disorder. What is Post-Traumatic Stress Disorder (PTSD)? Who develops PTSD? What are the symptoms of PTSD? Why do some people develop PTSD and other people do not? How is PTSD Treated? How can I hep a friend or relative who has PTSD? How can I help mysel
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f? Where can I go for help? What if I know someone in crisis? Next Steps for PTSD Research.
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Factsheet on PTSD | Most of us have had frightening experiences. Often we think about them long after the event. For some people, these distressing thoughts or images persist, as well as other symptoms such as a strong sense of threat, feeling emotionally numb, and irritability. If these reactions o
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ccur frequently, last at least a month, and interfere with daily functioning, the person may be suffering from PTSD.
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This Review summarizes many of the persistent biological alterations associated with childhood maltreatment including changes in neuroendocrine and neurotransmitter systems and pro-inflammatory cytokines in addition to specific alterations in brain areas associated with mood regulation. Finally, I d
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iscuss several candidate gene polymorphisms that interact with childhood maltreatment to modulate vulnerability to major depression and PTSD and epigenetic mechanisms thought to transduce environmental stressors into disease vulnerability.
Neuron Review, vol. 89, March 2, 2016 pp.892-909
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What it is and what you can do
Rev. Oct16 770-10-0003
Includes a Special Report on the Financial and Personal Benefits of Early Diagnosis
2018 Alzheimer’s Disease Facts and Figures is a statistical resource for U.S. data related to Alzheimer’s disease,
the most common cause of dementia. Background and context for interpretating the data are con
...
tained in
the Overview. Additional sections address prevalence, mortality and morbidity, caregiving and use and costs of health care and services. A Special Report discusses the financial and personal benefits of diagnosing earlier in the disease process, in the stage of mild cognitive impairment.
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Conventional and and atypical antipsychotics & antidepressant (trazodone) for behavioural and psychological symptoms in people with dementia
World Health Organization
(2012)
C_WHO
Q3: For behavioural and psychological symptoms in people with dementia, do following drugs, when compared to placebo/comparator, produce benefits/harm in the specified outcomes?
Bull World Health Organ 2013;91:773–783 | doi: http://dx.doi.org/10.2471/BLT.13.118422
(Submitted: 15 February 2013 – Revised version received: 21 June 2013 – Accepted: 22 June 2013 – Published online: 20 August 2013)