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Establishment of PCR laboratory in developing countries, 2nd ed.
recommended

World Health Organization ( WHO), Regional Office for South-East-Asia (2016) C_WHO

Polymerase Chain Reaction (‎PCR)‎ has significantly helped in early diagnosis and commencement of specific interventions for diseases control. It also plays a critical role in understanding the disease epidemiology and unraveling the transmission dynamics of the disease. This manual intends to p... more

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A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

Y.-H. Jin; L. Cai; Z.-S. Cheng; et al. Military Medical Research; Bio Med Central (2020) CC

Jin et al. Military Medical Research (2020) 7:4 https://doi.org/10.1186/s40779-020-0233-6 Position Article und Guideline

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Decontamination and waste management. Laboratory Biossafety Manual

World Health Organization WHO (2020) C_WHO

Laboratory Biossafety Manual

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Product profile for a rapid test for diagnosis of Buruli ulcer at the primary health-care level

Diagnostics Technical Advisory Group (DTAG) World Health Organization WHO (2022) C_WHO

In 2013, WHO and the Foundation for Innovative New Diagnostics convened a meeting of Buruli ulcer experts in Geneva, Switzerland (9) at which two priority unmet needs in diagnosis were identified: a diagnostic test for early detection of Buruli ulcer in symptomatic patients with sufficient positive... more

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Specifications and quantities for efficient procurement of essential equipment and laboratory commodities for HIV

Francis Aboagye-Nyame, Heather Alexander, Zelalem Gizachew Belachew et al. World Health Organization (2015) C_WHO

Second Edition AIDS Medicines and diagnostics services July 2015

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Handbook on TB laboratory diagnostic methods in the European Union

European Centre for Disease Prevention and Control (2016) C1

The aim of this handbook is to provide network members and other laboratories involved in the diagnosis of tuberculosis, with an agreed list of key diagnostic methods and their protocols in various areas of TB diagnosis, ranging from microbiological diagnosis of active TB to the diagnosis of latent ... more

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Zika virus (ZIKV) Surveillance in the Americas: Laboratory detection and diagnosis
recommended

Pan American Health Organization PAHO; World Health Organization, Regional Office for the Americas (2016) C_WHO

This algorithm is addressed to laboratories with established capacity(molecular, antigenic and/orserological) to detect dengue (DENV), Zika (ZIKV), and chikungunya(CHIKV) as part of the differential diagnosis for arborviruses. A BSL2 containment level is required to handle suspected samples.

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High risk and rapid appearance of multidrug resistance during tuberculosis treatment in Moldova

H. E. Jenkins, V. Crudu, V. Soltan, et al. National Institute of Health (2014) C2

Eur Respir J. 2014 April ; 43(4): 1132–1141. doi:10.1183/09031936.00203613.

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Establishing a national laboratory quality system for HIV diagnosis and monitoring in resource-limited settings: Experience from Senegal

Mbengue M.A.S., Moussa S., Papa A. D. et. al. African Journal of Laboratory Medicine (2016) C2

Senegal has adopted the World Health Organization–Joint United Nations Programme on HIV/AIDS recommended 90-90-90 targets.5 The adoption of this strategy means that the country is expected, by 2020, to have 90% of its population living with HIV diagnosed, 90% of all those diagnosed receiving susta... more

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SARS-CoV-2 antigen-detecting rapid diagnostic tests: An implementation guide

World Health Organization WHO (2021) C_WHO

This guide provides an overview of the major elements that must be considered before, during and after the implementation of antigen-detecting rapid diagnostic tests (Ag-RDTs) for SARS-CoV-2. This guide is complementary to policy guidance issued by ... more

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Manual for the laboratory diagnosis and virological surveillance of influenza

World Health Organization WHO (2011) C_WHO

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Target product profile for a rapid test for diagnosis of Buruli ulcer at the primary health-care level

World Health Organization WHO (2022) C_WHO

In 2009, WHO’s Second International Conference on Buruli Ulcer Control and Research resolved to strengthen the capacity of national laboratories to confirm cases of the disease, but advised that “efforts are still needed to develop simple diagnostic tools usable in the field as well as disabilit... more

Quality and safety practices for malaria rapid testing services

World Health Organization WHO (2022) C_WHO

This document is a guide defining requirements for quality and safety for malaria rapid diagnostic testing services to safeguard the quality of the results, the safety of the operators and patients and that of the environment for use by national mal... more

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Tuberculosis. Practical guide for clinicians, nurses, laboratory technicians and medical auxiliaries

Médecins sans Frontières MSF (2022) C2

This Tuberculosis guide has been developed jointly by Médecins Sans Frontières and Partners In Health. It aims at providing useful information to the clinicians and health staff for the comprehensive management of tuberculosis. Forms of susceptible and resistant tuberculosis, tuberculosis in child... more

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Good Practices for Selecting and Procuring Rapid Diagnostic Tests for Malaria

WHO (2011) C_WHO

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Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy

World Health Organization (WHO) (2017) C_WHO

The objectives of these guidelines are to provide recommendations outlining a public health approach to managing people presenting with advanced HIV disease, and to provide guidance on the timing of initiation of antiretroviral therapy (ART) for all people living with HIV.
WHO recommends that a... more

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National Guidelines for HIV-1 Viral Load Laboratory Testing
recommended

Government of India, Ministry of Health and Family Welfare, National AIDS Control Organisation (NACO) (2018) C1

The National Guidelines for HIV-1 Viral Load Laboratory Testing support plans to scale up viral load (VL) testing to reach the 90-90-90 targets in India. This phased scale-up includes the setup of 70 additional VL testing laboratories nationally. Th... more

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Vigilancia del virus Zika (ZIKV) en las Américas: Detección y diagnóstico por laboratorio

Organización Panamericana de la Salud Organización Mundial de la Salud, Oficina Regional para las Américas (2016) C_WHO

Este algoritmo está dirigido a aquellos laboratorios que cuentan con capacidad instalada para la detección (molecular, antigénica y/o serológica) de dengue (DENV), Zika (ZIKV) y chikungunya(CHIKV),y como parte del diagnóstico diferencial para Arbovirus. Para la manipulación de muestras sosp... more

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Management of a cholera epidemic - Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries, water and sanitation specialists and logisticians
recommended

Médecins Sans Frontières MFS (2023) CC

Cholera is a transmissible diarrhoeal infection caused by Vibrio cholerae. Endemic and/or epidemic in over 40 countries (mainly in Africa and Asia), cholera continues to be a major global public health issue. The World Health Organization (WHO) estimates that the number of cases reported worldwid...e represents in reality only 5 to 10% of actual cases. This guide is intended for medical and non-medical staff responding to a cholera outbreak. It attempts to provide concrete answers to the questions and problems faced by staff, based on the recommendations of reference organisations, such as WHO and UNICEF, as well as Médecins Sans Frontières’ experience in the field. It is divided into 8 chapters. Chapter 1, Cholera overview, outlines the epidemiological and clinical features of cholera. Chapter 2, Outbreak investigation, explains the method and stages of a field investigation, from the alert to implementation of initial activities. Chapter 3, Cholera control measures, details measures and tools to prevent and/or control cholera transmission and mortality in populations affected, or at risk of being affected, by an epidemic (curative care, prevention means and health promotion activities). Chapter 4, Strategies for epidemic response, addresses the roll-out strategies of the measures described in Chapter 3 which depend on context (e.g. urban, rural, endemic, non-endemic setting, etc.), resources and particular constraints. Chapter 5, Cholera case management, details the different stages of cholera treatment, from diagnosis through to cure. Chapter 6, Setting up cholera treatment facilities, focuses on the installation of treatment facilities that vary in size and complexity according to operational requirements (treatment centres and units and oral rehydration points). Chapter 7, Organisation of cholera treatment facilities, describes the organisation of these specialized facilities in terms of human resources, supply, water, hygiene and sanitation, etc. Chapter 8, Monitoring and evaluation, presents the key data to be collected and analysed during an epidemic to facilitate a tailored response and evaluate its quality and effectiveness. The guide includes various practical tools in the appendices to facilitate activities (e.g. water quality tests, job descriptions, documents, etc.). Moreover, the toolbox also contains additional tools in editable formats (individual patient file, cholera case register, pictograms). Despite all efforts, it is possible that certain errors may have been overlooked in this guide. Please inform the authors of any errors detected. To ensure that this guide continues to evolve while remaining adapted to field realities, please send any comments or suggestions. more

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WHO Prequalification of Diagnostics Programme - Public Report (Product: ABONtm HIV 1/2/O Tri-Line Human Immunodeficiency Virus Rapid Test Device, Number: PQDx 0141-051-00)

World Health Organization (2017) C_WHO

PQDx 0141-051-00 WHO PQDx Public Report April/2017, version 5.0

Establishment of PCR laboratory in developing countries, 2nd ed. recommended

Zika virus (ZIKV) Surveillance in the Americas: Laboratory detection and diagnosis recommended

National Guidelines for HIV-1 Viral Load Laboratory Testing recommended

Management of a cholera epidemic - Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries, water and sanitation specialists and logisticians recommended

Establishment of PCR laboratory in developing countries, 2nd ed.
recommended

Zika virus (ZIKV) Surveillance in the Americas: Laboratory detection and diagnosis
recommended

National Guidelines for HIV-1 Viral Load Laboratory Testing
recommended

Management of a cholera epidemic - Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries, water and sanitation specialists and logisticians
recommended