the aid library

Zika virus (ZIKV) Surveillance in the Americas: Laboratory detection and diagnosis
recommended

Pan American Health Organization PAHO; World Health Organization, Regional Office for the Americas (2016) C_WHO

This algorithm is addressed to laboratories with established capacity(molecular, antigenic and/orserological) to detect dengue (DENV), Zika (ZIKV), and chikungunya(CHIKV) as part of the differential diagnosis for arborviruses. A BSL2 containment level is required to handle suspected samples.

Ethiopia - National Cholera Control Operational Plan 2022/23

Government of Ethiopia (2023) CC

Cholera is a diarrheal disease caused by the bacterium Vibrio cholera. The infection primarily spreads through contaminated water and food. Symptoms include the onset of acute diarrhea and/or vomiting, muscle cramps, and body weakness. If untreated, the infection can result in ... more

Detection, Confirmation and Management of a Dysentery Outbreak caused by Shigella Dysenteriae type 1

Ministry of Health, Rwanda (2011) C2

Standard Operating Procedures | RBC/IHDPC/EID Division | 9/30/2011

A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

Y.-H. Jin; L. Cai; Z.-S. Cheng; et al. Military Medical Research; Bio Med Central (2020) CC

Jin et al. Military Medical Research (2020) 7:4 https://doi.org/10.1186/s40779-020-0233-6 Position Article und Guideline

WHO Prequalification of Diagnostics Programme - Public Report (Product: ABONtm HIV 1/2/O Tri-Line Human Immunodeficiency Virus Rapid Test Device, Number: PQDx 0141-051-00)

World Health Organization (2017) C_WHO

PQDx 0141-051-00 WHO PQDx Public Report April/2017, version 5.0

Standard Operating Procedures for Cholera Outbreak

Ministry of Health, Rwanda (2011) C2

Detection, confirmation and management Salmonella Typhi outbreak

Ebola virus disease preparedness strengthening team Guinea-Bissau country visit 12–20 November 2014

World Health Organization (2014)

The main objective of this mission was to assess the level of preparedness of Guinea-Bissau in respect of the WHO consolidated checklist. The checklist helps countries to assess and test their level of readiness it is being used to identify concrete action to be taken and where countries will requir ... more

Tuberculosis. Practical guide for clinicians, nurses, laboratory technicians and medical auxiliaries

Médecins sans Frontières MSF (2022) C2

This Tuberculosis guide has been developed jointly by Médecins Sans Frontières and Partners In Health. It aims at providing useful information to the clinicians and health staff for the comprehensive management of tuberculosis. Forms of susceptible and resistant tuberculosis, tuberculosis in child ... more

First meeting of the network on Buruli ulcer PCR laboratories in the WHO African Region Centre Pasteur du Cameroon, Yaoundé, 21–24 October 2019

World Health Organization WHO (2020) CC

Research to develop point-of-care tests is in progress. Treatment of Buruli ulcer comprises 8 weeks of combined antibiotics (rifampicin and clarithromycin). Complementary therapies such as wound care, skin graft and prevention of disability are needed in some cases to ensure full recovery. The targ ... more

Report of a WHO–FIND meeting on diagnostics for Buruli ulcer

WHO Tecnical Advisory Group and FIND (2018) CC

The meeting was held from 26 to 27 March 2018 to review and discuss the following topics: Advances and challenges in the use of fTLC, and new approaches to detecting mycolactone using monoclonal antibodies (mAbs). The status of development of rap ... more

Rapid Response to Ebola Outbreaks in Remote Areas — Liberia, July–November 2014

Centers for Disease Control and Prevention CDC (2015)

Morbidity and Mortality Weekly Report (MMWR):

Buruli ulcer : diagnosis of Mycobacterium ulcerans disease : a manual for health care providers

F. Portaels; Johnson, P.; Meyers, W. World Health Organization WHO (2001) CC

This manual is to assist health care providers and laboratory scientists to diagnose mycobacterium ulcerans disease (Buruli ulcer). The manual aims to achieve a better understanding of the clinical presentation and its diagnosis. The methods describ ... more

High risk and rapid appearance of multidrug resistance during tuberculosis treatment in Moldova

H. E. Jenkins, V. Crudu, V. Soltan, et al. National Institute of Health (2014) C2

Eur Respir J. 2014 April ; 43(4): 1132–1141. doi:10.1183/09031936.00203613.

Management of a cholera epidemic - Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries, water and sanitation specialists and logisticians
recommended

Médecins Sans Frontières MFS (2023) CC

Cholera is a transmissible diarrhoeal infection caused by Vibrio cholerae. Endemic and/or epidemic in over 40 countries (mainly in Africa and Asia), cholera continues to be a major global public health issue. The World Health Organization (WHO) estimates that the number of cases reported worldwid ... e represents in reality only 5 to 10% of actual cases. This guide is intended for medical and non-medical staff responding to a cholera outbreak. It attempts to provide concrete answers to the questions and problems faced by staff, based on the recommendations of reference organisations, such as WHO and UNICEF, as well as Médecins Sans Frontières’ experience in the field. It is divided into 8 chapters. Chapter 1, Cholera overview, outlines the epidemiological and clinical features of cholera. Chapter 2, Outbreak investigation, explains the method and stages of a field investigation, from the alert to implementation of initial activities. Chapter 3, Cholera control measures, details measures and tools to prevent and/or control cholera transmission and mortality in populations affected, or at risk of being affected, by an epidemic (curative care, prevention means and health promotion activities). Chapter 4, Strategies for epidemic response, addresses the roll-out strategies of the measures described in Chapter 3 which depend on context (e.g. urban, rural, endemic, non-endemic setting, etc.), resources and particular constraints. Chapter 5, Cholera case management, details the different stages of cholera treatment, from diagnosis through to cure. Chapter 6, Setting up cholera treatment facilities, focuses on the installation of treatment facilities that vary in size and complexity according to operational requirements (treatment centres and units and oral rehydration points). Chapter 7, Organisation of cholera treatment facilities, describes the organisation of these specialized facilities in terms of human resources, supply, water, hygiene and sanitation, etc. Chapter 8, Monitoring and evaluation, presents the key data to be collected and analysed during an epidemic to facilitate a tailored response and evaluate its quality and effectiveness. The guide includes various practical tools in the appendices to facilitate activities (e.g. water quality tests, job descriptions, documents, etc.). Moreover, the toolbox also contains additional tools in editable formats (individual patient file, cholera case register, pictograms). Despite all efforts, it is possible that certain errors may have been overlooked in this guide. Please inform the authors of any errors detected. To ensure that this guide continues to evolve while remaining adapted to field realities, please send any comments or suggestions. more

Methods for the detection and characterisation of SARS-CoV-2 variants: second update, 21 June 2022

World Health Organization WHO, Regional Office of Europe (2022) C_WHO

This document aims to provide interim guidance for microbiology and virology experts, other laboratory professionals, laboratory managers, infectious disease programme managers, public health profes ... more

Assessing the impact of imperfect immunoassays on HIV prevalence estimates from surveys conducted by the DHS program

Mathieu Maheu-Giroux, Lawrence Joseph, Patrick Belisle and others (2017) C2

This report investigates the impact of potential misclassification of samples on HIV prevalence estimates for 23 surveys conducted from 2010-2014. In addition to visual inspection of laboratory results, we examined how accounting for potential miscl ... more

Tool for the diagnosis and care of patients with suspected arboviral diseases

Pan American Health Organization PAHO ; World Health Organization WHO (2017) C_WHO

It is Zika virus (ZIKV) that most often causes these neurological effects it appears to be the only arbovirus than can cause congenital malformations such as microcephaly. In any case, more scientific tests are needed to establish the causal relationship between the virus and this malformation (7-10 ... more

Rapid ﬁeld entomological assessment during yellow fever outbreaks in Africa

World Health Organization WHO (2015) C_WHO

Methodological field approaches for scientists with a basic background in entomology to prepare and implement a yellow fever entomological assessment during outbreaks

Responding to a polio outbreak. Guidelines
recommended

Polio Global Eradication Intiative (2011)

The occurrence of a case of wild polio in a previously polio free area as presently in Syria, whether through importation, laboratory accident, or mutation of vaccine virus (VDPV), should be considered a public health emergency, that requires a ... more