This threat assessment addresses the implications of the ongoing Marburg virus disease (MVD) outbreak in
Rwanda for the European Union/European Economic Area (EU/EEA). MVD is a severe disease in humans and,
although uncommon, it has the potential to cause epidemics with significant case fatality.
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All recorded MVD
outbreaks to date have originated in Africa. MVD is not an airborne disease and is considered not to be
contagious before symptoms appear. Direct contact with the blood and other body fluids of infected people
and animals or indirect contact with contaminated surfaces and materials like clothing, bedding and medical
equipment is required for transmission. The risk of infection is minimised when proper infection prevention and
control precautions are strictly followed. There is no approved treatment or vaccine for MVD; however, several
pharmaceuticals and candidate MVD vaccines are under investigation.
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Death investigation form tuberculosis: Hospital Unit, Urgency and Emergency Unit
Death investigation sheet concerning tuberculosis: Other Health Units and with family members
Summary sheet Conclusion of death investigation concerning tuberculosis
Information on 102 commonly used medicinal plants in the South Pacific WHO regional publications. Western Pacific series ; Plants from this part of the world represent an especially diverse flora and include several species currently undergoing scientific
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investigation. Common traditional uses include the treatment of minor injuries, childhood ailments, and complications of pregnancy. Plants described in the book are also used as emetics and as ointments and dressings applied to surface wounds or used to treat skin problems.
Addressed to ethnobotanists, phytochemists, and pharmacologists, the book aims to document traditional clinical uses and bring these to the attention of the international scientific community, while also preserving knowledge about the distinctive indigenous practices in these island communities. Full-colour photographs are included to facilitate identification of plants and plant parts used for medicinal purposes. Each plant is described according to a common format, which includes information on scientific name, local names, English name, a description of the plant and its habitat and distribution, and a summary of what is known about its chemical constituents, biological activity, and traditional uses.
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At the end of this course, you should be able to:
- Draft an outbreak management plan for managing COVID-19 cases and outbreaks onboard ships;
- Manage an outbreak of COVID-19 disease on board a ship;
- Perform follow-up epidemiological and environmental
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investigation.
Target audience:
- National IHR Focal Points
- Port health authorities (PHAs) and local, provincial, and national health surveillance and response systems
- Ship operators and port operators
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Climate change has important implications for the health and futures of children and young people, yet they have little power to limit its harm, making them vulnerable to climate anxiety. This is the first large-scale investigation of climate anxiet
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y in children and young people globally and its relationship with perceived government response.
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Donor funding for HIV programs has increased rapidly over the past decade, raising questions about whether other health services in recipient-country health systems are being crowded out or strengthened. This article--an investigation of the impacts
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of increased HIV donor funding on non-HIV health services in sub-Saharan Africa during 2003-10--provides evidence of both effects.
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This data set represents the best estimates of WHO using methodologies for specific indicators that aim for comparability across countries and time; they are updated as more recent or revised data become available, or when there are changes to the methodology being used. Therefore, they are not alwa
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ys the same as official national estimates, although WHO whenever possible will provide Member States the opportunity to review and comment on data and estimates as part of country consultations. Note that these numbers are subject to change due to ongoing reclassification, retrospective investigation and availability of laboratory results. Please check the Indicator and Measurement Registry for indicator specific information.
In this section you will find data and statisticss:
Countries with intense transmission
Other affected countries
Download most recent available data
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In 2016 WHO introduced the Cholera Kits. These kits replace the Interagency Diarrhoeal Disease Kit (IDDK) which had been used for many years. The Cholera Kit is designed to be flexible and adaptable for preparedness and outbreak response in different contexts. The overall Cholera Kit is made up of a
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n Investigation Kit, Laboratory materials, 3 Treatment Kits (community, periphery and central) and a Hardware Kit. The Treatment and Hardware Kits are each composed of individual modules. Each of the kits and modules can be ordered independently based on field need. To support orders, a Cholera Kit Calculation Tool was developed.
The information note, packing lists and the Kit Calculation Tool are all available from the WHO website at: http://www.who.int/cholera/kit/en/
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Monkeypox is a viral zoonotic disease, caused by monkeypox virus, recognized as the most important orthopoxvirus infection after the eradication of smallpox.
This course offers public health officers and health workers in-depth information to understand the epidemiology, modes of transmission, clin
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ical presentation, diagnostics, and treatment of monkeypox, as well as the strategies needed for effective prevention and outbreak investigation and response.
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A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatmen
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t of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans. ; Supports further investigation by summarizing state of the art in the field of Buruli ulcer research Enriches understanding of epidemiology of Buruli ulcer in different geographic regions Reviews exhaustively the characteristics of Mycobacterium ulcerans disease
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Clinical Child Psychology and Psychiatry Volume 28, Issue Pages 3-14
The Russian invasion of Ukraine on 24th February 2022 has prompted this article to summarise some of the salient mental health issues experienced by young asylum seekers and refugees focussing on resettlement countries, drawing on
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the substantial literature, for Child and Adolescent Mental Health Practitioners. Firstly, the various UNHCR categories of persons affected by war and persecution and statistics are described. By July 2022, over 100 million people globally were of concern to UNHCR, a number increased by the many millions of refugees fleeing Ukraine to neighbouring countries. Selected findings on the psychiatric epidemiology of young refugees are summarised, and some principles of Child and Adolescent Mental Health Service delivery and treatments are outlined. The research on Ukrainian refugees’ mental health is limited and this is an area that requires further investigation alongside active attempts to meet their mental health needs.
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HIV-1 infection disproportionately affects women in sub-Saharan Africa, where areas of high HIV-1 prevalence and Schistosoma haematobium endemicity largely overlap. Female genital schistosomiasis (FGS), caused most frequently by S. haematobium egg deposition in the genital tract, has been associated
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with prevalent HIV-1 infection in cross-sectional studies. The presence of S. haematobium eggs in genital tissue is also associated with vascularization and the accumulation of CD4+ lymphocytes and macrophages, making the granuloma-associated environment a potential contributor to HIV-1 vulnerability. In addition to modulation of the local cervicovaginal environment, FGS has also been associated with a higher frequency of systemic CD4 T-cells expressing the chemokine receptor CCR5. Tissue-entrapped eggs are also associated with clinically visible FGS-associated manifestations in the cervicovaginal mucosa. FGS lesions may breach the intact cervicovaginal immune barrier and are hypothesized to provide an entry point for HIV-1 infection. However, the underlying mechanism for potential HIV-1 vulnerability in FGS has not been fully characterized and requires further investigation.
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Diagnosing asthma in children represents an important clinical challenge. There is no single gold-standard test to confirm the diagnosis. Consequently, over- and under-diagnosis of asthma is frequent in children. A task force supported by the European Respiratory Society has developed these evidence
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-based clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years using nine Population, Intervention, Comparator and Outcome (PICO) questions. The task force conducted systematic literature searches for all PICO questions and screened the outputs from these, including relevant full-text articles. All task force members approved the final decision for inclusion of research papers. The task force assessed the quality of the evidence using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.
The task force then developed a diagnostic algorithm based on the critical appraisal of the PICO questions, preferences expressed by lay members and test availability. Proposed cut-offs were determined based on the best available evidence. The task force formulated recommendations using the GRADE Evidence to Decision framework.
Based on the critical appraisal of the evidence and the Evidence to Decision framework, the task force recommends spirometry, bronchodilator reversibility testing and exhaled nitric oxide fraction as first-line diagnostic tests in children under investigation for asthma. The task force recommends against diagnosing asthma in children based on clinical history alone or following a single abnormal objective test. Finally, this guideline also proposes a set of research priorities to improve asthma diagnosis in children in the future.
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A paper presented at the 10th International Congress on Infectious Disease, Singapore
Ebola Virus Disease Outbreak Response Plan in West Africa Annex 3