The larval stage of the parasite Taenia solium can encyst in the central nervous system causing neurocysticercosis, which is the main cause of acquired epilepsy in the countries in which the parasite is endemic. Endemic areas are those with the presence (or likely presence) of the full life cycle of... Taenia solium. The parasite is most prevalent in poor and vulnerable communities in which pigs roam free, open defecation is practiced, basic sanitation is deficient, and health education is absent or limited. Several tools are available for the control of Taenia solium. Preventive chemotherapy for Taenia solium taeniasis, which is directed at the adult tapeworm, is one of them. Other tools focus on pig management, pig vaccination and treatment, sanitation and hygiene, and community education. Three potential drugs—niclosamide, praziquantel, and albendazole—have been considered for use for preventive chemotherapy in Taenia solium taeniasis control programs through mass drug administration or targeted chemotherapy. In this Guideline, we provide recommendations for preventive chemotherapy in Taenia solium-endemic areas using niclosamide, praziquantel, or albendazole, including at which dose and in which population groups.
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The internationally recognized criteria for diagnosis of neurocysticercosis include a requirement for neuroimaging techniques, such as computerized tomography (CT) and/or magnetic resonance imaging (MRI), ideally supported by serology. These facilities are not available in all settings, especially i...n rural areas of low-income countries, making it difficult to identify and treat patients. Additionally, there is controversy about the role, type and duration of anthelmintic, antiinflammatory and antiepileptic drug (AED) treatments for different forms of neurocysticercosis.
These guidelines were developed to assist health-care providers in appropriate, evidence-based management of parenchymal neurocysticercosis. The guidelines do not address other forms of neurocysticercosis and do not include management of extraparenchymal disease (including cysticerci in the cerebral ventricles or subarachnoid space). The aim of the guidance is to improve decision-making to ensure appropriate patient care and to avoid misdiagnoses and inappropriate treatment of patients with neurocysticercosis.
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Visión de conjunto:
El ciclo de transmisión
Teniasis. Las tenias viven en los intestinos de las personas infectadas. Los huevos de la tenia se liberan con las heces. Si se defeca al aire libre, se puede contaminar el ambiente (incluyendo los vegetales y el agua). Cisticercosis humana. La inges...tión de huevos de la tenia (debido a una mala higiene después de ir al baño o al consumir alimentos o agua contaminados), resulta en quistes del parásito principalmente en el cerebro (causando convulsiones y epilepsia). Cisticercosis porcina. Los cerdos que ingieren huevos de tenia (presentes en las heces o en el medio ambiente) desarrollan quistes del parásito, principalmente en los músculos (carne). La carne infectada contiene quistes del parásito, que no siempre son fáciles de ver. Comer carne de cerdo infectada cruda o poco cocinada hará que las personas desarrollen tenias.
Las medidas de prevención y control
Tratar la infección por teniasis con medicamentos indicados por el personal de salud. Lavarse las manos con agua y jabón después de ir al baño. Lavar bien las verduras o cocinarlas antes de comerlas. Utilizar los baños o letrinas para evitar infectar el ambiente, los cerdos y otras personas. Mantener a los cerdos en corrales para evitar que se infecten. Vacunar y tratar a los cerdos para prevenir la infección. La inspección de la carne puede identificar a los cerdos altamente infectados. Cocinar bien la carne de cerdo (no debe verse el color rosa) para matar el parásito.
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Vue d’ensemble:
Le cycle de transmission
Téniase. Les ténias vivent dans l’intestin des êtres humains. Les œufs du ténia sont libérés avec les matières fécales. En cas de défécation à l’air libre, l'environnement (en particulier les légumes et l'eau) peut être contaminé. Cysti...cercose humaine. L'ingestion d'œufs de ténia (due à une mauvaise hygiène après l'utilisation des toilettes ou à la consommation d'eau ou d'aliments contaminés), entraîne le développement de kystes parasitaires principalement dans le cerveau (provoquant notamment des crises d’épilepsie). Cysticercose porcine. Les porcs mangeant des œufs de ténia (présents dans les matières fécales ou l'environnement) développent des kystes parasitaires principalement dans les muscles (viande). La viande infectée contient des kystes parasitaires qui ne sont pas toujours faciles à voir. La consommation de viande de porc infectée, crue ou mal cuite, entraîne le développement du ténia.
Les mesures de prévention et de contrôle
Les médicaments prescrits dans les centres de santé peuvent traiter l'infection par le ténia. Lavez vos mains avec de l'eau et du savon après avoir utilisé les toilettes. Rincez soigneusement les légumes ou faites-les cuire avant de les manger. Utilisez les toilettes ou les latrines pour éviter la contamination de l'environnement, des porcs et des autres personnes. Garder les porcs dans des enclos pour les empêcher d’être infectés. Vaccinez et traitez les porcs pour prévenir l'infection. L'inspection des viandes permet d'identifier les porcs fortement infectés. Faites bien cuire la viande de porc (elle ne doit plus être rose) pour tuer le parasite.
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How to prevent the pork tapeworm? A neglected parasitic infection caused by Taenia solium - A neglected parasitic infection caused by Taenia solium. Available in different languages
Infographic: Preventing and controlling neglected parasitic zoonoses: a key role for the animal health sector
This manual summarizes key issues related to the safety of NTD medicines and their administration, with a focus on essential medicines used in mass drug administration (MDA), also called preventive chemotherapy. It can be used as a standalone reference manual, but is intended to be used in conjuncti...on with the accompanying training modules, which provide practical instruction, and the aide-mémoires. Versions of the aide-mémoires and training modules are available respectively for both (i) programme managers and district-level health officials and (ii) community drug distributors and community health workers
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The World Health Organization (WHO) and the global community of countries, partners, donors, technical experts, scientists and field implementation teams continue to work towards the ultimate goal of a world free of the burden of neglected tropical diseases (NTDs).
The road map sets global targets and milestones to prevent, control, eliminate or eradicate 20 diseases and disease groups as well as cross-cutting targets aligned with the Sustainable Development Goals. Three foundational pillars will support global efforts to achieve the targets: accelerate progra...mmatic action (pillar 1), intensify cross-cutting approaches (pillar 2) and change operating models and culture to facilitate country ownership (pillar 3).
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The road map 2030 was developed by WHO through an extensive global consultation, with indicators set for measuring progress against targets and milestones. This compendium of indicators provides a comprehensive and standardized listing of recommended indicators, including the 70 core indicators pres...ented in the M&E framework. These indicators will also support reporting on strategies described in other road map companion documents to guide action against neglected tropical diseases include the sustainability framework, the global strategy on water, sanitation and hygiene, the One Health approach and the strategic framework for integrated control and elimination of skin-related neglected tropical diseases.
The purpose of this compendium is to guide monitoring and evaluation of programmes and thereby to improve their quality and effectiveness in alignment with the road map goals. It provides a standardized listing of the most widely used indicators relevant to countries, with uniformity in defining indicators to allow comparisons over time and among different programmes. Detailed metadata are provided for each of these indicators to facilitate validity, internal consistency, standardized measurement, estimation methods and comparability of data across countries.
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В дорожной карте по борьбе с забытыми тропическими болезнями на 2021–2030 гг. («дорожная карта») определены глобальные цели и основные этапы в отношении борьбы с 20 бол...знями и группами болезней, их элиминации или полной ликвидации. В ней также определены сквозные целевые показатели, согласованные с Тринадцатой общей программой работы ВОЗ и Целями в области устойчивого развития, а также стратегии по достижению этих целевых
показателей в течение ближайших десяти лет.
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The document presents briefly Mozambique's profile on neglected tropical diseases, as well as recommendations on how to control them.
This Course for Service Providers on how to give Vitamin A Supplementation and Deworming (VAS+D) uses both a Learner’sGuide and a Facilitator’s Guide. The Learner’s Guide is designed for participants in the course who are healthcare workers or trainers learning to deliver vitamin A and Albenda...zole(for deworming) as part of regular activities associated with community or facility-based health care services, while the Facilitator’s Guide is designed for course facilitators who are planning and conducting courses .
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Information for policy-makers and planners on conducting deworming as part of an integrated
school health program
Chromoblastomycosis (CMB) is a chronic fungal infection of the skin and the subcutaneous tissue caused by a transcutaneous traumatic inoculation of a specific group of dematiaceous fungi occurring mainly in tropical and subtropical zones worldwide. If not diagnosed at early stages, patients with CBM... require long term therapy with systemic antifungals, sometimes associated with physical methods. Unlike other neglected endemic mycoses, comparative clinical trials have not been performed for this disease. Nowadays, therapy is based on a few open trials and on expert opinion. Itraconazole either as monotherapy or associated with other drugs, or with physical methods, is widely used. Recently, photodynamic therapy has been successfully employed in combination with antifungals in patients presenting with CBM. In the present revision the most used therapeutic options against CBM are reviewed as well as the several factors that may have impact on the patient's outcome.
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BMJ Open 2021;11:e042279. doi:10.1136/bmjopen-2020-042279. Neglected tropical diseases tend to cluster in the same poor populations, and to make progress with their control, they will have to be dealt with in an integrated manner. Peptide microarrays may be a solution to tese problems, where diagnos...is for co-infection can be detected simultaneously using the one tool.
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Primary Care: The Community Health System