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21 January 2022 The overall threat posed by Omicron largely depends on four key questions: (i) how transmissible the variant is; (ii) how well vaccines and prior infection protect against infection, transmission, clinical disease and death; (iii) how virulent the variant is compared to other varian ... more
Developed by the HHS Panel on Treatment of Pregnant Women with HIV Infection and Prevention of Perinatal Transmission— A Working Group of the Office of AIDS Research Advisory Council (OARAC) Accessed: 12.02.2020
This Mpox SPRP Global Monitoring & Evaluation (M&E) Framework, also referred to as the Framework, aims to monitor and report on global progress towards these objectives, including information about country-level response efforts and WHO support to Member States. Regular collection and analysis of da ... more

Guideline Treatment of tuberculosis in patients with HIV co-infection

Department of Health; Queensland Government (2019) C2
Version 3.0 Accessed: 24.11.2019
Available in Arabic, Chinese, English, French, Portuguese and Spanish https://apps.who.int/iris/handle/10665/334254
Cervical cancer, along with maternal deaths, has been identified as a national priority in South Africa as well as other Sub-Saharan African countries. Cervical cancer is the second most common cancer among women in South Africa, after breast cancer. Due to limited access to prevention, early dia ... more
This pocket guide offers basic information needed for the medical management of victims of radiation incidents in an easy-to-understand manner.
This Guide contains information, guidelines, diagrams and other materials addressed to medical practitioners who are engaged in the treatment of casualties of chemical weapons. It is made available to the public for information purposes, but is not intended to be used by the public. All decisions re ... more
"Patient decontamination principles are set forth here from a strategic perspective, rather than a tactical one. The principles are meant to guide, but not specify, operational practices. The guidance is evidencebased to the extent possible and the supporting evidence is documented and briefly dis ... more
These guidelines provide a recommendation on iodine thyroid blocking (ITB), via oral administration of stable iodine, as an urgent protective action in responding to a nuclear accident. This recommendation aims to support emergency planners, policy makers, public health specialists, clinicians and o ... more

A Decision Makers Guide: Medical Planning and Response for a Nuclear Detonation

U.S. Department of Health & Human Services (2017) C1
Successful detonation of an improvised nuclear device (IND) would be a catastrophic event, causing an unprecedented number of injuries and lives lost, as well as economic, political, and social disruption. However, an effective medical response and an infrastructure prepared to protect itself from f ... more
The potential for terrorist use of chemical agents is a noted concern highlighted by the Tokyo sarin gas attacks of 1995. The events of September 11, 2001, increased congressional attention towards reducing the vulnerability of the United States to such unconventional attacks. The possibility that ... more
"This document has been developed for outpatient oncology facilities to serve as a model for a basic infection control and prevention plan. It contains policies and procedures tailored to these settings to meet minimal expectations of patient protections as described in the CDC Guide to Infecti ... more
Basic Expectations for Safe Care

Introduction à la maladie d’Ebola: Contrôle des risques infectieux

Formenty, Pierre Organisation Mondiale de la Santé (OMS) (2018) C_WHO
Руководство ВОЗ по политике и практике информирования о рисках при чрезвычайных ситуациях (ИРЧС)
The goal of this Global Action Plan is to articulate synergistic actions that will be required to prevent HIVDR from undermining efforts to achieve global targets on health and HIV, and to provide the most effective treatment to all people living with HIV including adults, key populations, pregnant ... more
À l’heure où des techniques innovantes de dépistage sur le lieu de soins (POC) sont mises sur le marché, le présent rapport soumet à l’attention des gouvernements un examen des principaux aspects relatifs à leur introduction et à leur extension au sein des programmes publics nationaux. L ... more
The National Guidelines for HIV-1 Viral Load Laboratory Testing support plans to scale up viral load (VL) testing to reach the 90-90-90 targets in India. This phased scale-up includes the setup of 70 additional VL testing laboratories nationally. These guidelines include laboratory design considerat ... more
Operational Guidelines
In order to maintain daily operations and patient care services, health care facilities need to develop an Emergency Water Supply Plan (EWSP) to prepare for, respond to, and recover from a total or partial interruption of the facilities’ normal water supply. Water supply interruption can be caused ... more
(Health Systems in Transition, Vol. 4, No. 3, 2014)
The strategic priorities of the CCS 2014–2018 are:
(1) Strengthening the health system.
(2) Enhancing the achievement of communicable disease control targets.
(3) Controlling the growth of the noncommunicable disease burden.
(4) Promoting health throughout the life course.
... more
Submitted to the US Agency for International Development by the Systems for Improved Access to Pharmaceuticals and Services (SIAPS) Program. Arlington, VA: Management Sciences for Health. Submitted to the United Nations Children’s Fund by JSI, Arlington, VA: JSI Research & Training Institute, Inc. ... more
Soumis à l’Agence des États-Unis pour le développement international par le programme SIAPS (Systems for Improved Access to Pharmaceuticals and Services ou Programme des systèmes pour l’amélioration de l’accès aux produits et services pharmaceutiques). Arlington, VA : Management Sciences ... more
The National Health Plan (NHP) aims to strengthen the country’s health system and pave the way towards Universal Health Coverage (UHC),choosing a path that is explicitly pro-poor. The main goal of NHP 2017-2021 is to extend access to a Basic Essential Package of Health Services (EPHS) to the entir ... more
This document was prepared in response to a need to review and potentially update the current recommendations for the antibiotic treatment of both inpatient and outpatient management of severe acute malnutrition (SAM). The current recommendations (Table 1) are based on guidelines published in 2013 i ... more
Global UNIDO Project: Strengthening the local production of essential medicines in least developed and developing countries
Overcoming barriers in low- and middle-income countries For the first time, this year’s report includes information on hepatitis C diagnostics. With a focus on selected countries with diverse HCV epidemics, the report provides updates on the various dimensions of access to HCV diagnostics and pha ... more

Understanding PTSD Treatment (Guide)

National Center for PTSD U.S. Department of Veterans Affairs (2011) C2
This guide covers: Treatment That Works; Myths About Treatment; Success Stories; Resources | Do you or a loved one have PTSD? There is no need to suffer. Treatment works. If you have PTSD—posttraumatic stress disorder — you don’t have to suffer. There are good treatments that can help. This b ... more
Médecins sans Frontières access campaign Issue Brief Accessed: 28.11.2019
A practitioner’s guide to the principles of COVID-19 vaccine communications. The factors that lead people to make choices to take vaccines are nuanced and affected by how they see the world, their perceptions of the choices people like them will make, who they trust, their perceptions of risk, ... more

Substance Abuse Policy in Thailand: Current Challenges and Future Strategies

Darika Saingam Ashdin Publishing Journal of Drig and Alcohol Research (2018) C2
Review Article
Prepared as an outcome of ICMR Subcommittee on Breast Cancer |.This consensus document on management of breast cancers summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also inter ... more
Prepared as an outcome of ICMR Subcommittee on Cancer Cervix | This consensus document on management of cervix cancer summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also interwe ... more
Prepared as an outcome of ICMR Subcommittee on Multiple Myeloma | This consensus document on management of multiple myeloma summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also i ... more
These guidelines have been developed specifically to address ethical issues of conducting research in children.
These guidelines have been developed for scientific purpose with the main aim to guide the regulatory authority for evaluating probiotic products in our country.
The guidelines reiterate that the general principles of ethics for biomedical research involving human participants shall also be applicable. In addition, the guidelines specify unique provisions for stem cells, because of their inherent property for unlimited proliferation, differentiation to cells ... more
UNAIDS 2016 / Meeting Report
This document outlines the working structure and guiding principles for collaboration of COVAX, the Vaccines pillar of the Access to COVID-19 Tools Accelerator (ACT-A). The working structure of COVAX continues to adapt to emerging needs and the changing trajectory of the pandemic. Some components of ... more
Mental Health Information
Abstract: Posttraumatic stress disorder (PTSD) is a chronic psychological disorder that can develop after exposure to a traumatic event. This review summarizes the literature on the epidemiology, assessment, and treatment of PTSD. We provide a review of the characteristics of PTSD along with associa ... more
This Practice Parameter reviews the evidence from research and clinical experience and highlights significant advances in the assessment and treatment of posttraumatic stress disorder since the previous Parameter was published in 1998. It highlights the importance of early identification of posttrau ... more
Information booklet on Post Traumatic Stress Disorder. What is Post-Traumatic Stress Disorder (PTSD)? Who develops PTSD? What are the symptoms of PTSD? Why do some people develop PTSD and other people do not? How is PTSD Treated? How can I hep a friend or relative who has PTSD? How can I help mysel ... more

Basics of Alzheimer's disease

Alzheimer's Association Alzheimer's Association (2016) C2
What it is and what you can do Rev. Oct16 770-10-0003
Includes a Special Report on the Financial and Personal Benefits of Early Diagnosis 2018 Alzheimer’s Disease Facts and Figures is a statistical resource for U.S. data related to Alzheimer’s disease, the most common cause of dementia. Background and context for interpretating the data are con ... more
20 February 2013 Update on 2004 Background Paper (Written by Saloni Tanna) Priority Medicines for Europe and the World "A Public Health Approach to Innovation"
Q3: For behavioural and psychological symptoms in people with dementia, do following drugs, when compared to placebo/comparator, produce benefits/harm in the specified outcomes?

Infections of the nervous system

V. Parikh; V. Tucci; S. Galwankar PMC (US National Library of Medicine National Institutes of Health) (2012) C2
Int J Crit Illn Inj Sci. 2012 May-Aug; 2(2): 82–97. doi: 10.4103/2229-5151.97273 PMCID: PMC3401822 PMID: 22837896
Ann Indian Acad Neurol. 2015 Sep; 18(Suppl 1): S2–S5. doi: 10.4103/0972-2327.164812 PMCID: PMC4604693 PMID: 26538844
Last updated on Oct 5, 2018.

Strategies to prevent diversion of opioid substitution treatment medications

European Monitoring Centre for Drugs and Drug Addiction (2016) C2
Perspectives on Drugs

Case studies for regulatory approaches to tobacco products

World Health Organization (2018) C_WHO
Menthol in tobacco products
Si usted se ha sentido así durante por lo menos seis meses y estos sentimientos le hacen difícil hacer las tareas cotidianas, como hablar con otros en el trabajo o en la escuela, es posible que usted tenga un trastorno de ansiedad social.
¿Hay ocasiones en que tiene ataques repentinos de ansiedad y temor abrumador que duran varios minutos? Tal vez el corazón le late rápidamente, comienza a sudar y siente como si no pudiera respirar o pensar. ¿Estos ataques ocurren en momentos impredecibles sin ningún factor desencadenante obvio ... more
Position Statement Diabetes Care2018;42(Suppl. 1):S1–S194.
Introduction Chapter A.7
Mood disorders Chapter E.1 2015 edition
Mood disorders Chapter E.4 2018 edition
Anxiety disorders Chapter F.1 2018 edition
Anxiety disorders Chapter F.2
Anxiety disorders Chapter F.3
Psychiatry and Pediatrics Chapter I.4

ADHD - Parents Medication Guide

American Academy of Child & Adolescent Psychiatry and American Psychiatric Association; Elaine Schlosser Lewis Fund (2013) C2
Attention-Deficit/Hyperactivity Disorder

Guía para padres sobre medicamentos

American Academy of Child & Adolescent Psychiatry and American Psychiatric Association; Elaine Schlosser Lewis Fund (2013) C2
TDAH
Introducción Capítulo A.7 Edición en español Editor: Juan José García-Orozco Traducción: Juan José García-Orozco y Carlos González Vivas Revisor de traducción: Laura Borredá Belda
Trastornos del ánimo Capítulo E.1 Traducción de la versión inglesa del 2015
Trastornos del ánimo Capítulo E.2 Editores: Matías Irarrázaval & Andres Martin Traductores: Traducción: Fernanda Prieto-Tagle & Ester Mora
Trastornos des ánimo Capítulo E.4 Edition 2018 Editores: Matías Irarrázaval & Andres Martin Traducción: Fernanda Prieto-Tagle & María Vidal
Trastornos de ansiedad Capítulo F.3 Editores: Laura Revert, Matías Irarrázaval & Andres Martin Traducción: Régis Villegas, Paula Placencia, José Ángel Alda & Paula Cox
Trastornos de ansiedad Capítulo F.1 Edición en español Editor: Matías Irarrázaval Traducción: Matías Irarrázaval y María Tatiana Estefan
(2015) Scoping question: Are antidepressants (specifically, tricyclic antidepressants and selective serotonin reuptake inhibitors) effective and safe in adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective?
Trouble de l'humeur Chapitre E.2 Edition en français Traduction : Xavier Benarous Sous la direction de : David Cohen Avec le soutien de la SFPEADA
Troubles de l'humeur Chapitre E.1 Edition en français Traduction : Marie Boussaud, Julie Brunelle Sous la direction de : David Cohen Avec le soutien de la SFPEADA
Troubles Anxieux Chapitre F.3 Edition en français Traduction : Alexis Revet Sous la direction de : Jean-Philippe Raynaud Avec le soutien de la SFPEADA
Troubles anxieux Chapitre F.1 Edition en français Traduction : Jean-Philippe Raynaud Avec le soutien de la SFPEADA
Roubles de l’humeur Chapitre E.4 Edition en français Traduction : Cora Cravero Sous la direction de : David Cohen Avec le soutien de la SFPEADA
Psiquiatría y pediatría Capítulo I.4 Edición: Matías Irarrázaval & Andres Martin Traductores: Fernanda Prieto-Tagle & Juan Jairo Ortiz Guerra
These WHO interim recommendations on the use of the Pfizer – BioNTech BNT162b2 vaccine against Covid-19 were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document referenced below. fir ... more
Misceláneo Capítulo J.10 Edición: Matías Irarrázaval & Andres Martin Traducción: Fernanda Prieto-Tagle
Le trouble anxiété de séparation (TAS) représente environ la moitié de l’ensemble des troubles anxieux (Cartwright-Harton et al, 2006). La plupart des troubles anxieux pédiatriques présentent les mêmes critères diagnostics que chez l’adulte à l’exception du TAS, actuellement class ... more
Dialogues Clin Neurosci. 2017 Jun; 19(2): 93–107.
Globally each year, millions of people suffer illness or lose their lives because the vaccines, medicines and diagnostic tests that they need are either unavailable or unaffordable – and this lack of access to medicine is acute in low- and middle-in- come countries (LMICs). While the COVID-19 pan ... more
Accessed April 16, 2019
The National Action Plan (NAP) has been developed based on the model recommended in the global Action Plan. Local data on on-going interventions were collected from technical informants in the various areas of work. These were analysed using the policy framework provided by the AMR policy document. ... more
Este documento ha sido concebido para proporcionar un marco que respalde los estudios de prevalencia de las ITS en los niveles local y nacional. El propósito de estos estudios es conocer la carga de las infecciones por NG y CT, dos ITS prioritarias que dan lugar a resultados obstétricos y perinata ... more

Диагностика и лечение туберкулеза с множественной лекарственной устойчивостью возбудителя

Васильева Ирина Анатольевна, Самойлова Анастасия Геннадьевна, Эргешов Атаджан Эргешович et al. федеральное государственное бюджетное учреждение центральный научно-исследовательский институт туберкулеза российской академии медицинских наук, Американский международный союз здравоохранения (2012) C2
Cовершенствование теоретических знаний и практических навыков по вопросам диагностики и лечения туберкулеза с множественной лекарственной устойчивостью (МЛУ) ми ... more
Это руководство предназначено для использования в качестве пособия дл яврачей и других медицинских работников, осуществляющих лечение и уход за больными лекарст ... more